Image3_Effect of Rumex dentatus on Gastrointestinal Protection and Toxicology in Rodents via Investigating H+/K+-ATPase, Calcium Channels, and PDE Mediated Signaling.tiff by Neelam Gul Qazi (13178827)

“…Extracts and emodin also show an inhibitory effect against H⁺/K⁺-ATPase. Rumex dentatus showed a gastroprotective and antioxidant effect. Histopathological evaluation showed improvement in cellular architecture and decrease in the expression of inflammatory markers such as cyclooxygenase (COX2), tumor necrosis factor (TNF-α), and phosphorylated nuclear factor kappa B (p-NFƙB), validated through immunohistochemistry, ELISA, and western blot techniques. …”

Data_Sheet_1_Organic-Inorganic Hybrid Planarization and Water Vapor Barrier Coatings on Cellulose Nanofibrils Substrates.docx by Feyza Karasu (1909087)

“…However, the permeability of such materials to oxygen and water vapor is very sensitive to moisture, which limits their potential for a variety of packaging and encapsulation applications. …”

Data acquired from testing the effect of PAR1 inhibitors on Plasmodium falciparum-induced loss of endothelial cell barrier function by Janet Storm (8266991)

“…</div><div><br></div><div>The files are as follows:</div><div><div><b>-Combined analysis data for fig 2_TEER_includes normalisation.csv</b></div><div><b>-Combined analysis data for fig5_TEER_includes normalisation.csv</b></div><div><b>-Combined analysis data for fig6_TEER_includes normalisation.csv</b></div><div><b>-Data for fig2A+B+C_TEER_EA cells+inhibitors+thrombin_3.csv</b></div><div><b>-Data for fig2C_TEER_EA cells+inhibitors+thrombin_1.csv</b></div><div><b>-Data for fig2C_TEER_EA cells+inhibitors+thrombin_2.csv</b></div><div><b>-Data for fig3_flow cytometry HBMEC.csv</b></div><div><b>-Data for fig4A_TEER_aPC+thrombin_all time points shown.csv</b></div><div><b>-Data for fig4B_TEER_RBC+IE+lysate_all time points shown.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_#04-2+#91-2.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_#91-1.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_E5555-1+#04-1.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_E5555-2.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_Vorapaxar-1.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_Vorapaxar-2.csv</b></div><div><b>-Data for fig6_TEER_lysate_Vorapaxar+E5555+#04+#91-1.csv</b></div><div><b>-Data for fig6_TEER_lysate_Vorapaxar+E5555+#04+#91-2.csv</b></div><div><b>-Data for fig6_TEER_lysate_Vorapaxar+E5555+#04+#91-3.csv</b></div></div><div><br></div><div>The related publication investigated the hypothesis that the Thrombin-PAR1 coagulation/inflammation axis plays a significant role in barrier loss in cerebral malaria (CM), and that adjunct treatments targeting this might alleviate mortality or post-CM neurological sequelae in CM. …”

Induced dicentrics are variably stable over time. by Kaitlin M. Stimpson (243903)

The schematic diagram of the effects of inhibitors on protease activation and cartilage degradation. by Yi He (408132)

“…In summary, the activation of pro-enzyme is a key point in cartilage degradation of T+O treated bovine cartilage, which is regulated in an integrated cascade process.…”

Effects of cyclic stretch on cell reorientation. by Masataka Morioka (341795)

“…Total cell number (frequency) was set as 100% and the frequency in each group was expressed relative to the total cell number. (<b>E</b> and <b>F</b>) The mean and standard deviation (SD) of the cell orientation at each time point. …”

Somatosensory Abnormalities for Painful and Innocuous Stimuli at the Back and at a Site Distinct from the Region of Pain in Chronic Back Pain Patients by Christian Puta (390154)

“…Additionally, CLBP patients showed decreased pain thresholds at both sites. Importantly, there was no interaction between the investigated site and group, i.e. thresholds were changed both at the affected body site and for the site distinct from the painful region (hand). …”

Peripheral blood (PB) indices are similar in <i>NHD13</i> and <i>NHD13/Rag1</i>KO mice. by Sheryl M. Gough (323307)

“…(E) Representative FACS analysis of PB from mice of each genotype, aged 8 months, stained with the indicated antibodies.…”

CCDC6 knock down alters proliferation rate and increases cell death <i>in vitro</i>. by Angeliki Thanasopoulou (332490)

“…(<b>E</b>) Apoptotic cell death was analyzed by Po-PRO and 7-ADD staining. …”

Perfusion recovery. by Yinghuan Cen (3170154)

“…In group HD, the perfusion ratio was significantly elevated to 1.47–1.53 immediately post-surgery and each time point within 28 days. In group HID, the perfusion ratio slightly elevated immediately post-surgery and peaked to 1.69 on day 3 but decreased gradually after that and the ratio dropped to 1.25 on day 28 post-surgery.…”

Jip3 scaffolds lysosomes to DLIC for retrograde transport. by Catherine M. Drerup (383296)

“…Pink and yellow arrowheads point to two retrograde Jip3/Lamp1 positive cargos. …”

Short-read polishing tool benchmarking results using six clusters of genomes with real ONT and Illumina reads. by Ryan R. Wick (4096429)

Granuloma scores. by Masahiro Ishizuka (795418)

“…<p>The granuloma scores were obtained by counting the numbers of granulomata individually at 100 × magnification. Each data point represented average number of granulomata from 10 microscopic fields from H&E stained lung section from one mouse. …”

FGF signalling regulates expression of <i>osx</i>. by Katharina Felber (839136)

“…<p>(A-H) Larvae were treated at 48hpf, fixed at 51hpf and expression of several bone markers was analysed by in situ hybridisation. Arrowheads point to the opercle in the high magnification images to the right of each panel. …”

PAK1 Expression in schizophrenia. by Anthony J. Deo (251830)

“…Points above the line indicate increased expression in schizophrenia subjects, points below the line indicate decreased expression in schizophrenia subjects. …”

Morphology of the chromatoid body in <i>Sam68^−/−</i> germ cells. by Valeria Messina (318557)

“…Abnormalities in the CB morphology were also commonly observed in <i>Sam68^−/−</i> late round spermatids, such as decreased amount of the chromatoid material (<b>E</b>) or excess space between the CB lobes (<b>F</b>). …”

Cathepsin K transgenic mice (black bars) and wild-type mice (white bars) were administered either saline or bleomycin for 1, 2, 3, and 4 weeks by Mrigank Srivastava (94935)

“…Total BAL fluid cell numbers (A), alveolar macrophages (B), exudate macrophages (C), neutrophils (D) and lymphocytes (E) were ascertained from Pappenheim-stained cytospin preparations of BAL fluid. …”

The onset, abundance and fitness of generalists. by Shenshen Wang (488302)

“…Above (marked by arrows) generalists are on average fitter than specialists; this requires a higher level of fitness conservation as ruggedness decreases (e.g. for <i>K</i> = 11 whereas for <i>K</i> = 3). …”

Detection of 1′′–3′ gcADPR in lysates of bacteria expressing the SARM1 TIR domain. by Jeremy Garb (18405156)

“…Bar graphs represent the average of three independent replicates, with individual data points overlaid. Asterisk marks statistically significant decrease (Student’s <i>t</i>-test, two-sided, <i>P</i> <0.05).…”

Data Sheet 1_Association of dietary index for gut microbiota and cardiovascular diseases in American adults: evidence from National Health and Nutrition Examination Survey 1999–201... by Hong Luo (205745)

“…Mediation analysis examined the role of body mass index (BMI).</p>Results<p>A total of 39,181 participants (mean age: 47.15 years) were included, with 49.18% female and 50.82% male. …”