Data_Sheet_1_The role of immune suppression in COVID-19 hospitalization: clinical and epidemiological trends over three years of SARS-CoV-2 epidemic.PDF by Marta Canuti (336637)

“…The proportion of immune suppressed patients among all hospitalizations (initially stable at <20%) started to increase around December 2021, and remained high (30–50%). This change coincided with an increase in the proportions of older patients and patients with co-morbidities and with a decrease in the proportion of patients with severe outcomes. …”

Table_1_Narrowing row spacing and adding inter-block promote the grain filling and flag leaf photosynthetic rate of wheat under enlarged drip tube spacing system.xlsx by Jianguo Jing (18767383)

“…The decline of NS22 (9.93%) was higher than that of NS44 (9.04%), and both cultivars also showed a greater decrease in grain weight and average grain-filling rate (AGFR) of inferior grains (NS22: 23.19%, 13.97%; NS44: 7.78%, 5.86%) than the superior grains (NS22: 10.60%, 8.33%; NS44: 4.89%, 4.62%). …”

DataSheet_1_Narrowing row spacing and adding inter-block promote the grain filling and flag leaf photosynthetic rate of wheat under enlarged drip tube spacing system.zip by Jianguo Jing (18767383)

“…The decline of NS22 (9.93%) was higher than that of NS44 (9.04%), and both cultivars also showed a greater decrease in grain weight and average grain-filling rate (AGFR) of inferior grains (NS22: 23.19%, 13.97%; NS44: 7.78%, 5.86%) than the superior grains (NS22: 10.60%, 8.33%; NS44: 4.89%, 4.62%). …”

Age-related effects of the COVID-19 pandemic on mental health of children and adolescents by Stefanie J. Schmidt (6259154)

“…Adolescents experienced a significantly larger decrease in emotional and behavioural problems than both preschoolers and school-children. …”

Image1_Total flavonoids extracted from Penthorum chinense Pursh mitigates CCl4-induced hepatic fibrosis in rats via inactivation of TLR4-MyD88-mediated NF-κB pathways and regulatio... by Sujuan Wang (1865149)

“…Subsequently, rats were randomly assigned to a control group (Control), a carbon tetrachloride (CCl₄)-induced hepatic fibrosis model group (Model), a positive control group [0.2 mg/(kg∙day)] of Colchicine), and three TFPCP treatment groups [50, 100, and 150 mg/(kg∙day)]. …”

Image2_Total flavonoids extracted from Penthorum chinense Pursh mitigates CCl4-induced hepatic fibrosis in rats via inactivation of TLR4-MyD88-mediated NF-κB pathways and regulatio... by Sujuan Wang (1865149)

“…Subsequently, rats were randomly assigned to a control group (Control), a carbon tetrachloride (CCl₄)-induced hepatic fibrosis model group (Model), a positive control group [0.2 mg/(kg∙day)] of Colchicine), and three TFPCP treatment groups [50, 100, and 150 mg/(kg∙day)]. …”

Basal PLD activity is strongly stimulated by the D1/5R agonist and blocked by the D1/5R, mGluR5, mGluR1, and the PLD-linked mGluR antagonists in the amygdala of cocaine CPP animals... by Balaji Krishnan (203728)

“…The D1/5R antagonist, SCH23390, completely blocked basal PLD activity (91.2±21.9, n = 12, ^##<i>p</i><0.01) in the cocaine CPP group. A similar reduction in PEtOH levels was observed with application of either the PLD-linked mGluR antagonist, PCCG-13 (62.9±10.6, n = 7, ^##<i>p</i><0.01) or the mGluR1 antagonist, LY367385 (75.0±13.9, n = 12, ^##<i>p</i><0.01), while the mGluR5 antagonist, MPEP, did not decrease basal PLD activity (305.7±31.5, n = 7, ns) within the cocaine CPP group but were significantly increased compared to (*<i>p</i><0.05) the saline treated group. …”

Image_1_Archetypal type II and III Toxoplasma gondii oocysts induce different immune responses and clinical outcomes in experimentally infected piglets.tif by Andrea Largo-de la Torre (13985607)

“…Apathy and a moderate decrease in feed consumption were observed in G1 and G2 piglets between 5 and 8 dpi, coinciding with fever (>40°C). …”

Pattern convergence via scaling in single granule cells. by Antoine D. Madar (6619286)

“…<i>Left and Middle</i>: Mean+/-SEM. Blue indicates a significant difference from the identity line (one-sample t-test, p < 0.05). …”

CTL dynamics and the impact of recombination. by Rafal Mostowy (141881)

“…Panel A shows the mean diversity of the CTL population which decreases with increasing mean (except for an initial increase in avidity) and decreasing variance in avidity. …”

Plasma pharmacokinetics and brain uptake of 2B3-101 and pegylated liposomal doxorubicin in healthy mice. by Pieter J. Gaillard (506968)

The effect of the protein C pathway on the kinetics of Warfarin anticoagulation in patients with atrial fibrillation. by Jonathan H. Foley (277140)

Characteristics of the optimal network. by Veronika Koren (3691690)

“…Frequency of Up states decreases with increasing linear cost. At the optimal cost, indicated by an arrow, the frequency of Up states is close to zero, indicating that in the optimally efficient network, Up states are at the point of vanishing. …”

Endocycle is required for ecdysone biosynthesis. by Yuya Ohhara (3697570)

“…<p><b>(A)</b> Knockdown of <i>CycE</i> in the PG causes reduction in DNA content. …”

Data_Sheet_1_Influence of CO2 Degassing on the Microbial Community in a Dry Mofette Field in Hartoušov, Czech Republic (Western Eger Rift).CSV by Qi Liu (33068)

“…However, it remains open if the observed patterns can be generalized for different time-points or sites.</p>…”

Data_Sheet_13_Influence of CO2 Degassing on the Microbial Community in a Dry Mofette Field in Hartoušov, Czech Republic (Western Eger Rift).PDF by Qi Liu (33068)

“…However, it remains open if the observed patterns can be generalized for different time-points or sites.</p>…”

Image_2_Differences in Intercellular Communication During Clinical Relapse and Gadolinium-Enhanced MRI in Patients With Relapsing Remitting Multiple Sclerosis: A Study of the Compo... by Fabiana Geraci (3873664)

“…In contrast, the presence of lesions in the brain and spine on gadolinium-enhanced MRI was associated with an increase in the numbers of CCR3⁺/CCR5⁺ (subset of CD8 memory T cells), CD4⁺/CCR3⁺ (Th2 cells), and CD4⁺/CCR5⁺ (Th1 cells) CSF-EVs. Two points are worth emphasizing: (i) the data obtained in this study confirm that CSF-EVs represent a potentially promising tool to identify biomarkers specific for different phases of MS; and (ii) Considering the role of EVs in intercellular communication, our results provide some insights that improve our understanding of the relationships among some of the cell types that are mainly involved in MS pathogenesis (e.g., lymphocytes, glia, and neurons).…”

The Ca²⁺/PKC/p115 signaling axis enables persistent RhoA signaling. by Jason Z. Zhang (9339291)

“…For all comparisons to +p63 condition: ****<i>P</i> < 0.0001; ordinary one-way ANOVA followed by Dunnett’s multiple-comparisons test (versus +p63). (<b>C-E</b>) Computational simulations of adding pyrilamine at different time points after histamine stimulation and measuring concentrations of active p63 (<b>C</b>), active p115 (<b>D</b>), or active RhoA (<b>E</b>). …”

Single-molecule properties of the Head1/Neck3 chimera. by Sarah Adio (374199)

“…Average velocities v (mean±s.e.m.) of NcKin wild type motor (closed circles <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004612#pone.0004612-Jaud1" target="_blank">[22]</a> and additional data points) and Head1/Neck3 chimera (open circles) are plotted versus applied load. …”

Image_3_Differences in Intercellular Communication During Clinical Relapse and Gadolinium-Enhanced MRI in Patients With Relapsing Remitting Multiple Sclerosis: A Study of the Compo... by Fabiana Geraci (3873664)

“…In contrast, the presence of lesions in the brain and spine on gadolinium-enhanced MRI was associated with an increase in the numbers of CCR3⁺/CCR5⁺ (subset of CD8 memory T cells), CD4⁺/CCR3⁺ (Th2 cells), and CD4⁺/CCR5⁺ (Th1 cells) CSF-EVs. Two points are worth emphasizing: (i) the data obtained in this study confirm that CSF-EVs represent a potentially promising tool to identify biomarkers specific for different phases of MS; and (ii) Considering the role of EVs in intercellular communication, our results provide some insights that improve our understanding of the relationships among some of the cell types that are mainly involved in MS pathogenesis (e.g., lymphocytes, glia, and neurons).…”