LRP1 endocytosis is required for Aβ42 uptake and accumulation in N2a cells. by Rodrigo A. Fuentealba (362971)

“…The surface-to-total ratio were calculated and plotted as fold-change to control-infected cells. <i>Right panel</i>, decreased CHC levels and normal mLRP4 levels in transduced N2a-mLRP4 cells were verified by Western blot from sister cultures. …”

GDF11 regulates the EGF signal transduction pathway. by Gareth Williams (5148)

“…Exposure to GDF11 significantly decreases EGF receptor protein levels as shown by densitometric analysis relative to actin (mean ± SEM; *<i>p</i><0.05, **<i>p</i><0.01, n = 3) and by a representative blot. …”

Table_1_Circulating Reelin promotes inflammation and modulates disease activity in acute and long COVID-19 cases.pdf by Laurent Calvier (3339327)

“…CR-50 prophylactic treatment decreased mortality and disease severity in this model. …”

Table_1_Flow Cytometric Analysis of Bacterial Protein Synthesis: Monitoring Vitality After Water Treatment.DOCX by Mathilde Lindivat (9251252)

“…Protein synthesis activity and DNA integrity (BONCAT–SYBR Green) was monitored in Escherichia coli monocultures and in natural marine samples after UV irradiation (from 25 to 200 mJ/cm²) and heat treatment (from 15 to 45 min at 55°C). UV irradiation of E. coli caused DNA degradation followed by the decrease in protein synthesis within a period of 24 h. …”

Spry1 is essential to maintain hAoSMC marker gene expression. by Xuehui Yang (225729)

“…E) Representative immunoblot showing that knockdown of Spry1 results in a decrease in total Akt and ERK proteins levels, as well as pAkt and pERK. …”

Table_2_Comparable Stride Time Fractal Dynamics and Gait Adaptability in Active Young and Older Adults Under Normal and Asymmetric Walking.docx by Scott W. Ducharme (7124309)

“…<p>Previous research indicates the correlation structure of gait parameters (i.e., fractal dynamics) decreases with age. This decrease is suggested to reflect a reduced capacity for locomotor adaptation in older adults. …”

Cytokine Kinetics in the First Week of Tuberculosis Therapy as a Tool to Confirm a Clinical Diagnosis and Guide Therapy by Alice L. den Hertog (340331)

“…</p><p>Results</p><p>Changes in concentrations of non-specific host biomarkers, particularly IP-10, in response to the first week of anti-TB therapy were strongly associated with bacteriological confirmation of TB. …”

Supplementary Figure 2: VAC14 Knockdown and neuronal cell sensitivity to docetaxel or paclitaxel for additional morphological phenotypes from Pharmacogenetic Discovery in CALGB (Al... by Daniel L. Hertz (14989820)

“…For paclitaxel treatment at the same time point, the cells were also found to have significantly decreased sensitivity for D) relative mean process length and E) mean outgrowth intensity but not for F) relative straightness. …”

Data_Sheet_1_Land Degradation Changes the Role of Above- and Belowground Competition in Regulating Plant Biomass Allocation in an Alpine Meadow.pdf by Yong Zhang (5893)

“…To explore the issue, this study investigated the shoot-to-root (R/S) ratio, plant aboveground traits, and root competition of three functional groups (i.e., grasses, sedges, and forbs) at three degradation levels (i.e., no obvious degradation, ND; moderate degradation, MD; and severe degradation, SD) in an alpine meadow in the eastern Qinghai-Tibetan Plateau. …”

Tulp3 is a functional target of Zfp423. by Chen-Jei Hong (418943)

“…Graphs indicate high (red), medium (purple) and low (blue) translocation as in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1006357#pgen.1006357.g005" target="_blank">Fig 5D and 5E</a>. Dashed lines indicate values from <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1006357#pgen.1006357.g005" target="_blank">Fig 5E</a> for <i>ZNF423</i> knockdown alone (orange dashes) and non-targeting controls (black dashes). …”

Western blot analysis of respiratory-deficient mitochondrial cybrids by Deborah Pye (19680)

“…<p><b>Copyright information:</b></p><p>Taken from "Production of mitochondrial cybrids containing naturally occurring pathogenic mtDNA variants"</p><p>Nucleic Acids Research 2006;34(13):e95-e95.</p><p>Published online 2 Aug 2006</p><p>PMCID:PMC1540737.…”

Supplementary Material for: A Multicenter Pilot Study of a Bronchial Valve for the Treatment of Severe Emphysema by Sterman D.H. (4121239)

ZA-induced inhibition of HIF-1α activity and Pgp expression in MDR+ cancer cells. by Chiara Riganti (401982)

“…For panels <b>B</b> and <b>E</b> the bars represent the mean ± SD of 3 independent experiments.…”

Cells involved in extracellular matrix remodeling after acute myocardial infarction by Larissa Ferraz Garcia (10473506)

“…Markers of differentiated cells, E-cadherin (adhesion protein between myocardial cells), CD24 (protein present in the blood vessels), and alpha-1-actin (specific myocyte marker), showed higher expression in the groups submitted to gene therapy, compared to non-treated group. …”

PGRMC1 mediates the binding of Abeta oligomers to neurons <i>in vitro</i>. by Nicholas J. Izzo (659329)

“…In the presence of siRNA to sigma-2/PGRMC1, both Abeta oligomer binding and sigma-2/PGRMC1 expression are significantly reduced (<b>B, E</b>). Non-targeting siRNA (<b>C, F</b>) has no effect. …”

Data_Sheet_1_Acute stressors do not impair short-term memory or attention in an aged mouse model of amyloidosis.docx by Giuliana M. DiMarco (15456806)

“…We predicted stressor exposure would decrease performance accuracy more robustly in transgenic vs. non-transgenic mice. …”

Data_Sheet_1_Evaluating Impacts of Trophic Interactions on the Effectiveness of Single-Species Fisheries Management.docx by Lei Xing (129950)

“…The increase of fishing pressure to other species (i.e., non-target species) was beneficial to O. oratoria and S. schlegelii. …”

Data_Sheet_1_The Fate of Emotional Memories Over a Week: Does Sleep Play Any Role?.PDF by Nicola Cellini (5088965)

“…Our results suggest that emotional memories are resistant to forgetting, particularly when sleep is disrupted, and they are not affected by non-clinical depression symptomatology.</p>…”

The effects of YL-0919 in rats exposed to 4-week stress procedure. by Hong-xia Chen (499364)

“…Four-week stress procedure caused significant decrease in sucrose preference in stress-vehicle rats compared to control non-stressed rats. …”

Supplementary Material for: Trends in Adherence to Recommended Physical Activity and Its Association with Mortality and Disease Progression among US Adults with Chronic Kidney Dise... by Qu X. (14068626)

“…Multivariate regression models were used to evaluate the association between adherence to PAG and sedentary time with mortality, estimated glomerular filtration rate (eGFR), and urine albumin-to-creatinine ratio. <b><i>Results:</i></b> For the CKD population, adherence rate increased from 48.2% in 2007–08 to 55.0% in 2017–18, and sedentary time peaked in 2013–14 (7.5 h/day) and then decreased afterward. …”