Image_2_Neutrophil depletion in the pre-implantation phase impairs pregnancy index, placenta and fetus development.jpeg by Cristina Bichels Hebeda (5931599)

“…On gestational day 5.5, neutrophil depletion impaired the blastocyst implantation, as 50% of pregnant mice presented reduced implantation sites. …”

Is the lady's-slipper orchid (<i>Cypripedium calceolus</i>) likely to shortly become extinct in Europe?—Insights based on ecological niche modelling by Marta Kolanowska (471074)

“…According to these analyses all the scenarios of future climate change will result in the total area of niches suitable for <i>C</i>. <i>calceolus</i> decreasing. Considering areas characterized by a suitability of at least 0.4 the loss of habitat will vary between ca. 30% and 63%. …”

Image 1_Proteome changes during in vitro culture adaptation of Toxoplasma gondii archetypal II and III field isolates.tif by Joachim Müller (265589)

“…Interestingly, differentially abundant proteins were clearly linked to phenotypic changes associated to in vitro adaptation: loss of ability to spontaneously form cysts at high passages and decreased expression of cyst and bradyzoite markers (BAG1, Enolase 1, and SRS35A), while culture adaptation was associated with increased abundance of recognized virulence factors such as GRA15, GRA16, TEEGR and NSM.…”

Video_6_Aging dysregulates neutrophil extracellular trap formation in response to HIV in blood and genital tissues.mp4 by Laura Moreno de Lara (12966254)

“…<p>Women acquire HIV through sexual transmission, with increasing incidence in women >50 years old. Identifying protective mechanisms in the female genital tract (FGT) is important to prevent HIV-acquisition in women as they age. …”

Image_3_Alterations of Gut Microbiome and Metabolite Profiles Associated With Anabatic Lipid Dysmetabolism in Thyroid Cancer.tif by Ganghua Lu (12750878)

“…</p>Methods<p>16S rRNA gene sequencing and an integrated LC–MS-based metabolomics approach were performed to obtain the components and characteristics of fecal microbiota and metabolites from 50 patients with TC and 58 healthy controls (HCs).…”

Image_2_Altered Intra- and Inter-Network Connectivity in Drug-Naïve Patients With Early Parkinson’s Disease.TIF by Weiqi Zeng (4386472)

“…Additionally, our results support PD as a disconnection syndrome.</p>…”

The Effect of Garlic and Voluntary Exercise on Cardiac Angiogenesis in Diabetes: The Role of MiR-126 and MiR-210 by Roya Naderi (6098570)

“…On the other hand, there was a miR-210 expression increase in the myocardium of diabetic animals (p < 0.001). …”

Early CD8⁺-recovery independently predicts low probability of disease relapse but also associates with severe GVHD after allogeneic HSCT by Juha Ranti (5774918)

“…We found that CD8⁺ T-cell counts exceeding 50x10⁶/l as early as on day 28 post-transplantation correlated significantly with decreased relapse risk, with three-year relapse rates of 17.0% and 55.6% (P = 0.002), but were also associated with severe acute and chronic GVHD. …”

Image_3_Positive Effects of Neutrophil Elastase Inhibitor (Sivelestat) on Gut Microbiome and Metabolite Profiles of Septic Rats.tif by Yali Sun (2099593)

“…</p>Results<p>Sivelestat administration significantly improved the survival of septic rats (80% vs 50%, P = 0.047). Microbiome analysis showed that the microbiota composition of rats in the CLP group was significantly disturbed, as potential pathogens such as Escherichia-Shigella and Gammaproteobacteria became dominant, and the beneficial microbiota represented by Lactobacillus decreased. …”

Image_1_Positive Effects of Neutrophil Elastase Inhibitor (Sivelestat) on Gut Microbiome and Metabolite Profiles of Septic Rats.tif by Yali Sun (2099593)

“…</p>Results<p>Sivelestat administration significantly improved the survival of septic rats (80% vs 50%, P = 0.047). Microbiome analysis showed that the microbiota composition of rats in the CLP group was significantly disturbed, as potential pathogens such as Escherichia-Shigella and Gammaproteobacteria became dominant, and the beneficial microbiota represented by Lactobacillus decreased. …”

Table_7_Species-specific metabolome changes during salinity downshift in sub-Arctic populations of Mytilus edulis and M. trossulus.docx by Inna M. Sokolova (3857770)

“…Taurine emerged as the dominant osmolyte, comprising over 50% of the total free amino acid pool, with aspartate and glycine contributing 15–30%. …”

Table_1_Clinical study on endovascular recanalization of non-acute symptomatic middle cerebral artery occlusion.XLSX by Jinchao Xia (14211707)

“…From the low- to high-risk groups, the recanalization rate gradually decreased (100.0, 91.7, and 16.7%, respectively, P = 0.020), the perioperative complication rate gradually increased (0, 13.9, and 83.3%, respectively, P < 0.001), the proportion of the modified Rankin scale scores >2 at 90 days increased (0, 11.7, and 50.0%, P < 0.001), and the restenosis/reocclusion rates in the 73 cases of successful recanalization increased (0, 16.1, and 100%, P = 0.012) during follow-up.…”

DataSheet_1_The Hypoglycemic and Renal Protection Properties of Crocin via Oxidative Stress-Regulated NF-κB Signaling in db/db Mice.docx by Ye Qiu (363315)

“…</p>Methods<p>Eight-week-old db/db mice were treated with metformin (Met) (100 mg/kg) and CR (50 mg/kg) for eight weeks.</p>Results<p>CR treatment showed hypoglycemic functions indicated by reduced bodyweight, food and water intake, plasma glucose, and serum levels of glycated hemoglobin A1c. …”

Video_3_Aging dysregulates neutrophil extracellular trap formation in response to HIV in blood and genital tissues.mp4 by Laura Moreno de Lara (12966254)

“…<p>Women acquire HIV through sexual transmission, with increasing incidence in women >50 years old. Identifying protective mechanisms in the female genital tract (FGT) is important to prevent HIV-acquisition in women as they age. …”

Table_1_Positive Effects of Neutrophil Elastase Inhibitor (Sivelestat) on Gut Microbiome and Metabolite Profiles of Septic Rats.docx by Yali Sun (2099593)

“…</p>Results<p>Sivelestat administration significantly improved the survival of septic rats (80% vs 50%, P = 0.047). Microbiome analysis showed that the microbiota composition of rats in the CLP group was significantly disturbed, as potential pathogens such as Escherichia-Shigella and Gammaproteobacteria became dominant, and the beneficial microbiota represented by Lactobacillus decreased. …”

DataSheet_1_Changing trends in the disease burden of uterine cancer globally from 1990 to 2019 and its predicted level in 25 years.docx by Shuang Song (457799)

“…</p>Conclusions<p>UC has significantly impacted global health negatively, with its influence stemming from a range of factors including geographical location, age-related and racial disparities, and SDI.…”

Table_2_Species-specific metabolome changes during salinity downshift in sub-Arctic populations of Mytilus edulis and M. trossulus.docx by Inna M. Sokolova (3857770)

“…Taurine emerged as the dominant osmolyte, comprising over 50% of the total free amino acid pool, with aspartate and glycine contributing 15–30%. …”

Table_4_Species-specific metabolome changes during salinity downshift in sub-Arctic populations of Mytilus edulis and M. trossulus.docx by Inna M. Sokolova (3857770)

“…Taurine emerged as the dominant osmolyte, comprising over 50% of the total free amino acid pool, with aspartate and glycine contributing 15–30%. …”

Image_1_Alterations of Gut Microbiome and Metabolite Profiles Associated With Anabatic Lipid Dysmetabolism in Thyroid Cancer.tif by Ganghua Lu (12750878)

“…</p>Methods<p>16S rRNA gene sequencing and an integrated LC–MS-based metabolomics approach were performed to obtain the components and characteristics of fecal microbiota and metabolites from 50 patients with TC and 58 healthy controls (HCs).…”

Data Sheet 1_Total flavonoids isolated from Eucommia ulmoides can alleviate bone loss and regulate intestinal microbiota in ovariectomized rats.docx by Baocang Yin (20689031)

“…Ethnopharmacological relevance<p>Eucommia ulmoides, recognized as a traditional Chinese medicinal herb, can tonify liver and kidney and strengthen bones and muscles. …”