Image_2_Gonadotropin-Releasing Hormone Receptor-Targeted Near-Infrared Fluorescence Probe for Specific Recognition and Localization of Peritoneal Metastases of Ovarian Cancer.JPEG by Qiyu Liu (3961796)

“…The fluorescence signal of peritoneal metastases peaked in intensity at 2 h and maintained for up to 48 h. ICG also showed a weak signal in the tumor lesions due to the enhanced permeability and retention effect, but the intensity decreased quickly within 48 h.…”

Low Resolution Data-Independent Acquisition in an LTQ-Orbitrap Allows for Simplified and Fully Untargeted Analysis of Histone Modifications by Simone Sidoli (167157)

“…By exploiting an LTQ-Orbitrap mass spectrometer, we parallelized MS and MS/MS scan events using the Orbitrap and the linear ion trap, respectively, decreasing the total scan time. This, in combination with large windows for MS/MS fragmentation (50 <i>m</i>/<i>z</i>) and multiple full scan events within a DIA duty cycle, led to a MS scan cycle speed of ∼45 full MS per minute, improving the definition of extracted LC–MS chromatogram profiles. …”

Image_1_Cardiac Involvement in Human Immunodeficiency Virus Infected Patients: An Observational Cardiac Magnetic Resonance Study.TIFF by Chengxi Yan (9602174)

“…</p><p>Results: HIV-infected patients had lower left (55.3 ± 6.5 vs. 63.0 ± 7.9%, P < 0.001) and right ventricular systolic function (35.9 ± 15.7 vs. 50.8 ± 9.3%, P < 0.001). Radial systolic strain (30.7 ± 9.3 vs. 39.3 ± 9.4%, P = 0.001), circumferential systolic strain (−17.5 ± 2.6 vs. −19.4 ± 2.7%, P = 0.008), and longitudinal systolic strain (−9.4 ± 5.7 vs. −12.8 ± 3.1%, P = 0.012) were also decreased in HIV. …”

<b>The burden of diabetes mortality by county, race, and ethnicity in the USA, 2000–2019</b> by Hasan Nassereldine (14605604)

“…<p dir="ltr">Objective</p><p dir="ltr">Diabetes is a leading cause of death in the USA. Previous studies have found substantial racial and ethnic and geographical disparities in diabetes mortality, however research considering racial and ethnic and geographical disparities simultaneously has been limited. …”

Clinical Connections KG version 20240501 by Jennifer Hadlock (20465732)

“…<p dir="ltr">The <a href="https://github.com/NCATSTranslator/Translator-All/wiki/Multiomics-Clinical-Connections-KP" rel="noreferrer" target="_blank">Clinical Connections KG</a> is created and maintained by the <a href="https://github.com/NCATSTranslator/Translator-All/wiki/Multiomics-Provider" target="_blank">Multiomics Provider</a> team from the Institute for Systems Biology in Seattle, WA. …”

Mass spectrometry-based determination of APLP2 α- and β-shedding sites. by Sebastian Hogl (349573)

“…This peptide was analyzed in a mass spectrometer. (<b>B</b>) HEK293 cells were transiently transfected with the APLP2TF construct and either treated with TAPI-1 (50 µM) or DMSO as a solvent control. …”

Sensitivity analysis: estimated change in NHV rehabilitation effect based on different dropout imputation scenarios. by Xia Zhang (41398)

The neural processing of gestures accompanying figurative speech in a narrative context in patients with schizophrenia. Preliminary results from an fMRI study by Riedl (6892817)

“…</p> <p> <br> </p> <p> Results: In comparison to the healthy control group, the patients showed abnormal activation in left inferior frontal regions, but also in neighbouring regions (e.g. the frontoparietal operculum): Patients with schizophrenia compared to control subjects showed an increased activation for the SimNG condition and a decreased activation for the SimG condition.…”

Table1_Estimation of Mycophenolic Acid Exposure in Heart Transplant Recipients by Population Pharmacokinetic and Limited Sampling Strategies.DOCX by Xipei Wang (6473981)

“…Co-medication of PPIs decreased F by 27.6%. When eGFR decreased by 30 ml/min/1.73 m², CL/F decreased by 23.7%. …”

Image2_Estimation of Mycophenolic Acid Exposure in Heart Transplant Recipients by Population Pharmacokinetic and Limited Sampling Strategies.TIFF by Xipei Wang (6473981)

“…Co-medication of PPIs decreased F by 27.6%. When eGFR decreased by 30 ml/min/1.73 m², CL/F decreased by 23.7%. …”

Image1_Estimation of Mycophenolic Acid Exposure in Heart Transplant Recipients by Population Pharmacokinetic and Limited Sampling Strategies.TIF by Xipei Wang (6473981)

“…Co-medication of PPIs decreased F by 27.6%. When eGFR decreased by 30 ml/min/1.73 m², CL/F decreased by 23.7%. …”

TRLS2^-/- mice demonstrate appropriate hormone responses to low blood glucose. by Daniel W. Fisher (4872406)

“…Tukey’s <i>Post Hoc</i> Test p < 0.05) are decreased in <i>Trls2</i>^-/- mice. <b>G)</b> H&E sections (40x) of thyroid gland morphology is similar between <i>Trls2</i>^+/+ and <i>Trls2</i>^-/-, without signs of swollen follicles or dysplastic epithelial cells. …”

Density plots illustrating dispersions for the obtained lie indicator values. by Gáspár Lukács (9455157)

“…<p>In truthteller and liar conditions, using three different hypothetic lie detection devices: A, B, and C. Note that the decreasing overlap (largest for A, smallest for C) means an increase in efficiency for classification (i.e., the smaller the overlap, the better the classification). …”

Increasing branch occupancy with inhibitory synapses enhances Inhibitory Level at the junction but saturates relative inhibitory accumulation. by Christopher Brian Currin (7064300)

“…<p><b>(A)</b> The percentage of dendritic branches which have inhibitory synapses, “effective number of synapses”, indicates the diminishing return in additional IL when adding more synapses. …”

Xenobiotic response regulatory factors are specific to one or more cytoprotective pathways. by David E. Shore (123998)

“…Representative images of conditions with decreased cytoprotective gene expression are outlined in red, and the fold reduction in GFP expression, quantified in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002792#pgen-1002792-t001" target="_blank">Table 1</a>, is shown in the lower right. …”

Table_2_Associations between repetitive head impact exposure and midlife mental health wellbeing in former amateur athletes.docx by Claire V. Buddenbaum (18622372)

“…While not statistically significant, the contact group showed increased depressive [2.37 (0.05, 4.79), p=0.07] and ADHD symptoms [4.53 (0.51, 9.57), p=0.08] compared to controls. In a secondary analysis, a distinct trend emerged within the contact group, revealing pronounced elevations in mental health symptoms among individuals with lower socioeconomic status (<$50,000/year) compared to higher income subgroups, and these symptoms decreased as income levels rose [depression: -3.08 (-4.47, -1.7), p<0.001; anxiety: -1.95 (-3.15, -0.76), p=0.002; ADHD: -4.99 (-8.28, -1.69), p=0.004; PTSD: -4.42 (-7.28, -1.57), p=0.003; aggression: -6.19 (-11.02, -1.36), p=0.01]. …”

Low doses of IL-4 and IL-13 enhance cellular proliferation. by Quentin D’Arcy (13919516)

“…<p><b>A, B.</b> N1 and SFT1 prostate fibroblasts and HLF primary lung fibroblasts were cultured in serum-free defined media supplemented with vehicle or increasing doses (1–100 ng) of human recombinant IL-4 (<b>A</b>) or IL-13 (<b>B</b>) for 24 hours. …”

<i>cic</i> inactivation promotes ISC proliferation and hyper-activation inhibits ISC proliferation. by Yinhua Jin (838896)

“…Scale bars represent 20 μm in A-B and 50 μm in E-G.</p>…”

Image_1_Epidemiological and Clinical Characteristics of Five Rare Pathological Subtypes of Hepatocellular Carcinoma.pdf by Xiaoyuan Chen (322516)

“…</p>Results<p>Despite scirrhous carcinoma, which showed a decreasing trend (APC = -6.8%, P = 0.025), the morbidity of other rare subtypes remained stable from 2004 to 2018. …”

Image_1_Associations between repetitive head impact exposure and midlife mental health wellbeing in former amateur athletes.tiff by Claire V. Buddenbaum (18622372)

“…While not statistically significant, the contact group showed increased depressive [2.37 (0.05, 4.79), p=0.07] and ADHD symptoms [4.53 (0.51, 9.57), p=0.08] compared to controls. In a secondary analysis, a distinct trend emerged within the contact group, revealing pronounced elevations in mental health symptoms among individuals with lower socioeconomic status (<$50,000/year) compared to higher income subgroups, and these symptoms decreased as income levels rose [depression: -3.08 (-4.47, -1.7), p<0.001; anxiety: -1.95 (-3.15, -0.76), p=0.002; ADHD: -4.99 (-8.28, -1.69), p=0.004; PTSD: -4.42 (-7.28, -1.57), p=0.003; aggression: -6.19 (-11.02, -1.36), p=0.01]. …”