Showing 21 - 40 results of 27,834 for search '(( 50 ((a decrease) OR (nn decrease)) ) OR ((( 5 ht decrease ) OR ( 16 we decrease ))))', query time: 0.65s Refine Results
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    Synthesis and Biological Evaluation of Peripheral 5HT<sub>2B</sub> Antagonists for Liver Fibrosis by Jihyeon Yoon (8705706)

    Published 2025
    “…Recent studies have shown that antagonizing 5-hydroxytryptamine receptor 2B (5HT<sub>2B</sub>) stimulates the apoptosis of activated hepatic stellate cells and inhibits their proliferation while concurrently regressing hepatocyte proliferation. …”
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    Synthesis and Biological Evaluation of Peripheral 5HT<sub>2B</sub> Antagonists for Liver Fibrosis by Jihyeon Yoon (8705706)

    Published 2025
    “…Recent studies have shown that antagonizing 5-hydroxytryptamine receptor 2B (5HT<sub>2B</sub>) stimulates the apoptosis of activated hepatic stellate cells and inhibits their proliferation while concurrently regressing hepatocyte proliferation. …”
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    Pharmacological Mechanism of the Non-hallucinogenic 5‑HT<sub>2A</sub> Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

    Published 2022
    “…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G<sub>q</sub>, G<sub>11</sub>, and β-arrestin2) coupled to 5-HT<sub>2A</sub> receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”
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    Pharmacological Mechanism of the Non-hallucinogenic 5‑HT<sub>2A</sub> Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

    Published 2022
    “…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G<sub>q</sub>, G<sub>11</sub>, and β-arrestin2) coupled to 5-HT<sub>2A</sub> receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”
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    Statistical details of data presented in Fig 16. by Piotr Popik (292215)

    Published 2024
    “…<div><p>The rapid decrease of light intensity is a potent stimulus of rats’ activity. …”
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    Overview of the WeARTolerance program. by Ana Beato (20489933)

    Published 2024
    “…This research evaluates the "WeARTolerance’’ arts-based program in reducing mental health stigma among diverse youths. …”