Phase plot of the periodic orbits for progressive (Panel A) and alternating stepping (Panel B). by Hendrik Reimann (3778705)

Sensitivity analysis for IC₅₀ and <i>ε</i>_max as a function of measurement time. by Hope Murphy (8843516)

The IC50 value of Tan in normal esophageal HET-1A cells. by Dong Yang (141041)

Assessment of exoprotein concentration in a 50-mL culture of MH96. by Marion Schoof (11999106)

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

Frequency compensation in the feedback scheme of Fig 4a for a stepwise <i>k</i>₂ change (1.0 → 10.0) at background <i>k</i>₁₀ = 0.0. by Melissa Nygård (15374507)

Decrease in preferred walking speed with distance walked for subjects with amputation. by Nidhi Seethapathi (3258591)

NB polarity and number are unaffected by knockdown of mitochondrial morphology proteins. by Dnyanesh Dubal (12085942)

Analysis of change in mature INPs, GMCs and neurons in the type II NB lineage on depletion of mitochondrial morphology proteins. by Dnyanesh Dubal (12085942)

Host population bottlenecks decrease microbiome diversity. by Michael Ørsted (5926028)

Analysis of proliferation in NBs depleted of Opa1 and Marf. by Dnyanesh Dubal (12085942)

Depletion of Opa1 and Marf does not cause increase in the cleaved Caspase 3 levels and apoptosis in the brain. by Dnyanesh Dubal (12085942)

Notch signaling regulates fused mitochondrial morphology in INPs and muscle cells. by Dnyanesh Dubal (12085942)

Drp1^SD overexpression partially alleviates the differentiation defect seen in <i>notch</i> RNAi expressing type II NB lineages. by Dnyanesh Dubal (12085942)

Analysis of mitochondrial morphology in Notch mutants and Notch signaling in Opa1 depleted type II NB lineages. by Dnyanesh Dubal (12085942)

FTY720 decreased viability, proliferation, and motility and induced apoptosis in human hepatoblastoma cells. by Laura L. Stafman (6577184)

“…<p>(A) Following 24 hours of treatment with FTY720, the viability of HuH6 cells measured using the alamarBlue cell viability assay was significantly decreased (LD₅₀ = 8.4 μM, p ≤ 0.05). …”

Slope of sensitivity to feedback on several time steps. by Guillaume Deffuant (130910)

E₅₀ values. by Junxia Zhou (14381598)

Decreased expression of ATG5 upon the siRNA transfection. by Manisha Naskar (2613763)