Expression of neurotrophins and their receptors was decreased in <i>Slitrk6</i>-deficient inner ear. by Kei-ichi Katayama (257931)

“…Amounts of a neuronal marker (βIII tubulin) and a sensory epithelium marker (Myosin VIIa) were comparable between the wild-type and knockout mice. …”

The number of prospermatogonia is decreased in <i>Chtf18</i>^−/− neonatal testes. by Karen M. Berkowitz (123502)

rHSP60 decreases viability of B lymphocyte cell line but not macrophage one. by Igor Emiliano L. Souza (18196495)

MMP-9 expression is decreased in LV-shRNA-ADAMTS-1 transduced vessels. by Evelyn C. Nieves Torres (551495)

nLTD decreases the molecular proximity between endogenous spine cofilin and F-actin by Barbara Calabrese (553229)

“…Data are expressed as mean ± SEM of the “% FRET” values determined using the Zeiss LSM 510 software module for FRET acceptor photobleaching (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0094787#s2" target="_blank">Methods</a>); *p<0.05, **p<0.01 compared to control alone; ^#p<0.05 compared to nLTD alone; ^XXp<0.01 compared to CIN alone, two-way ANOVA, followed by Bonferroni post hoc test., (number of spines: ctrl = 43, nLTD = 29, CIN = 49, CIN+nLTD = 77). …”

Decreasing neural activity in MBONs that suppress PER when activated has modest effects. by Justine Chia (5459294)

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(D, E)</b> The free cholesterol and cholesterol ester levels in the ER membrane from the cells as in <b>(C)</b>, were quantified with shotgun lipidomics analysis (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s007" target="_blank">S7 Fig</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s012" target="_blank">S5 Table</a>) (mean ± SE, <i>n</i> = 3 independent experiments, **<i>P</i> < 0.01, *<i>P</i> < 0.05, nonsignificant (ns) two-sided Student’s <i>t</i> test). …”

Zebrafish harboring homozygous mutations in <i>gdf6</i> exhibit decreased endurance. by Michèle G. DuVal (278183)

“…</b> Open field tests of average swim velocity during 10 minutes of each hour through a circadian cycle, in tanks replicating lifetime husbandry conditions, show a lower mean movement at night (in either genotype, **p<0.01) but no difference between genotypes in any measure during day (p = 0.247) or night (p = 0.814).…”

Simvastatin decreases cerebral vasospasm of the middle cerebral artery and reduces microthromboemboli after SAH. by Mohammed Sabri (355717)

“…<p><b>A.</b> Representative images showing vasospastic MCA in vehicle treated mice, as compared to larger diameter MCAs from the two simvastatin treated groups that are similar to MCA in naïve group. …”

Hsp90 inhibition decreases the adipogenic transcriptional program without any effect on cytotoxicity. by Sébastien Desarzens (547289)

Total tau levels are significantly decreased in the healthy older brains compared to the younger brains. by Shreyasi Chatterjee (3531506)

Etomoxir and orlistat inhibit cell cycle progression and decreased proliferation rate in myeloma cells. by José Manuel Tirado-Vélez (304970)

Increased osteoblastic activity and decreased osteoclastogenesis in TgLRAP cells <i>in vitro</i>. by Naoto Haruyama (487384)

“…Relative ALP activities (<b>A</b>, at day 10) and accumulated calcium amount (<b>B</b>, at day 21) were statistically higher in the TgLRAP cells as compared to the WT (graphs). …”

Aspirin decreases expression of NFκB and β-catenin in colon cancer cells. by Satya Pathi (301408)

“…<p>Decreased p65/p50 in RKO (A) and SW480 (B) cells. Cells were treated for 48 hr with 5 or 10 mM, and whole cell, nuclear and cytosolic extracts were analyzed by western blot analysis as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0048208#s3" target="_blank">Experimental Procedures</a>. …”

Decreased ISCs and increased goblet cells after intestinal specific loss of MLL1. by Neha Goveas (11790822)

“…(B) Percent of weight loss of <i>Mll1</i>^{<i>FC/+; Vil-Cre-ERT2/+</i>} (n = 6) and of <i>Mll1</i>^{<i>FC/FC; Vil-Cre-ERT2/+</i>} (n = 10) mice. Mean ± s.d. is shown (p = 0.007, Student’s <i>t</i>-test). …”

Global Land Use Change Impacts on Soil Nitrogen Availability and Environmental Losses by Jing Wang (6206297)

“…Anthropogenic activities, particularly land use change and management practices, alter the global nitrogen (N) cycle. As a central part of the global N cycle, soil N supply from net N mineralization (NNM) and net nitrification (NN) contributes to over 50% of crop N uptake. …”

DHT increases whereas orchidectomy decreases the weight and cross sectional area of hindlimb muscles. by Young-Eun Yoo (323357)

“…<b>A:</b> In WT mice, DHT increased the GN weight by 7% (212.4±8.8 mg), whereas orchidectomy decreased it by 14% (171.4±9.0 mg) compared with control WT mice (198.4±5.5 mg). …”

Ethanol decreases hepatic ATP and causes modest liver injury: protection by Alda-1. by Zhi Zhong (314411)

Simultaneous ablation of Syt1 and Syt7 decreases the RRP size at excitatory synapses. by Taulant Bacaj (803415)

“…Experiments were performed as described for <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1002267#pbio.1002267.g001" target="_blank">Fig 1</a>, except that picrotoxin (50 μM) was used instead of CNQX. …”

GBE did not modify cell morphology but decreased reactive oxygen species (ROS) levels. by Virginie Rhein (243241)

“…<b>C</b>) Mitochondria-associated ROS levels measured after incubation with DHR (DHR fluorescence units/1×10⁵ cells). ROS levels showed a trend to be increased in APP cells compared to control cells (⁽*⁾p = 0.082, unpaired student's t-test, n = 11, values represent the means ± S.E.). …”