Rate of Genomic Size Change by Ploidy and Environment by Aleeza C Gerstein (21492)

“…Each data point thus represents the mean ± SE of five slope measures. This figure shows that haploids increased in genome size faster in salt, while tetraploids decreased in genome size more slowly in salt.…”

Coactivation and peak torque of extensors and flexors knee muscle in chronic hemiparetics in sitting and supine positions by Moisés Costa do Couto (4958161)

“…<p></p><p>ABSTRACT Disorders in co-activation and decreased muscle strength are often described in hemiparetic subjects. …”

Supplementary Material for: The Progression of Stargardt Disease (ProgStar) as determined by spectral-domain optical coherence tomography over a 24-month period (ProgStar Report No... by Strauss R.W. (5446388)

Supplementary Material for: The effect of an education module to reduce weight bias among medical centers employees: A randomized controlled trial by Sherf-Dagan S. (11983685)

Impact of Chronodisruption during Primate Pregnancy on the Maternal and Newborn Temperature Rhythms by María Serón-Ferré (5654170)

“…This rhythm was entrained in control newborns whereas LL newborns showed a random distribution of the acrophases over 24-h. In addition, mean temperature was decreased (34.0±0.6 vs 36.1±0.2°C, in LL and control, respectively P<0.05). …”

Inhibition of PI3K/Akt signal pathway increased chemotherapeutic sensitivity and promoted apoptosis of shRNA transfected cisplatin resitant cells. by Yan Wang (15435)

“…<p>A: A549DDP and H460DDP cells transfected with shRNA were treated with LY294002 (10 and 40 µM). …”

Functional validation of a miRNA-34a-TREM2–3’UTR interaction. by Surjyadipta Bhattacharjee (3181674)

“…<p><b>(A)</b> ribonucleotide sequence of the 299 nt TREM2-mRNA-3’-UTR is shown in the 5’-3’ direction; the 22 nt miRNA-34a-TREM2 3’UTR complementarity-interaction region is indicated by a black underline and the 8 nt TREM2-mRNA-3’-UTR seed sequence <b>5’-ACACUGCU-3’</b> is overlaid in yellow; a single arrowhead indicates the 5’ end of a poly A+ tail in the TREM2 mRNA (22 ‘A’ nt shown; the length of this poly A+ tail is variable); TREM2 mRNA sequence derived from NM_018965; TREM2 transcript is the major X1 variant (see also <a href="http://switchdb.switchgeargenomics.com/productinfo/id_801321/" target="_blank">http://switchdb.switchgeargenomics.com/productinfo/id_801321/</a>) (<b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.g003" target="_blank">Fig 3</a></b>); <b>(B)</b> TREM2-mRNA-3’UTR expression vector luciferase reporter assay (pLightSwitch-3’UTR; Cat#S801178; Switchgear Genomics, Palo Alto CA); in this vector, the entire 299 nucleotide TREM2 3’UTR was ligated into the unique Nhe1-Xho1 site; <b>(C)</b> control C8B4 murine microglial cells, 1 week in culture; phase contrast bright field microscopy 20x; C8B4 cells transfected with the TREM2-mRNA-3’UTR expression vector luciferase reporter were treated exogenously with miRNA-34a, a scrambled control miRNA-34a (miRNA-sc) or control miRNA-183; see references and text for further details [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.ref018" target="_blank">18</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.ref019" target="_blank">19</a>]; <b>(D)</b> compared to control, C8B4 cells transfected with a scrambled (<b>sc</b>) control pLightSwitch-3’UTR vector, the TREM2-mRNA-3‘UTR vector exhibited decreased luciferase signal to a mean of 0.16-fold of controls in the presence of miRNA-34a; this same vector exhibited no change in the presence of the control miRNA-34a-sc or miRNA-183; for each experiment (using different batches of MG cells) a control luciferase signal was generated and included separate appropriate controls with each analysis; in addition a control vector β-actin-3’UTR showed no significant effects on the relative luciferase signal yield after treatment with either miRNA-183 or miRNA-34a (data not shown); dashed horizontal line set to 1.0 for ease of comparison; N = 5; *<i>p</i><0.001 (ANOVA). …”

Human brain-derived clonal MSC upregulate immature neuronal markers and downregulate pericyte markers upon neuronal induction. by Gesine Paul (326199)

“…<p>QPCR in neural induction cultures. (A) After 10 days of neuronal induction, we observed a 180–200 fold upregulation of mRNA of the early neuronal markers DCX and β-III-tubulin and an about 50-fold increase in mRNA for GFAP, a glial marker and marker for neural progenitors. …”

Coordinate axes defining the Hb states. by Randall L. Barbour (3987236)

“…<p>Regions in (ΔdeoxyHb, ΔoxyHb) space that correspond to increasing or decreasing values, with respect to the temporal mean, for each commonly considered component of the Hb signal. …”

Dynamics of cell infiltration in wild type and MYOII-KD case. by Wanho Lee (3720238)

“…(F) Histograms of the average migratory speeds of rat glioma cells in the absence (red) and presence of (blue) 50 <i>μM</i> blebbistatin, a biochemical inhibitor of myosin II. …”

Steady state solutions for Case-1 (lower network viscosity). by Igor R. Kuznetsov (250256)

“…<p>Parameter values are as in the benchmark case (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0010082#pone-0010082-t001" target="_blank">Table 1</a>), except that the viscosity is lowered by a factor of 10. …”

Effects of resveratrol and BTP treatment on modulation of PCNA expression. by Jasmine George (345368)

“…^#significantly decreased when compared with groups IV and V (p<0.01).…”

Table_1_Measuring the frequency and distribution of meiotic crossovers in homozygous barley inbred lines.DOCX by Miriam Schreiber (529700)

“…We have previously shown that Hvmlh3 decreases both plant fertility and recombination by ~50%. …”

Cx43 and AQP4 astrocytopathy in active lesions of MS (case MS-3). by Katsuhisa Masaki (119851)

“…This lesion is classified as pattern A for Cx43 and pattern B for Cx47/Cx32. Scale Bar = 4 mm (A, B); 50 µm (C); 100 µm (D–K).…”

Possible risk factors for maternal neglect in MaD1 mice across multiple generations. by Stephen C. Gammie (89652)

“…For A–C, data from Generations (G) 12 and 15 were combined and for D and E, data from G6, G12, and G15 were combined. …”

Distal oligodendrogliopathy and astrocytopathy in anti-AQP4 antibody-seropositive NMO (case NMO-10). by Katsuhisa Masaki (119851)

“…This lesion is classified as pattern A for Cx43 and pattern B for Cx47/Cx32. Scale Bar = 4 mm (A–D); 200 µm (E–M); 50 µm (N, O); 20 µm (P, Q).…”

Presentation_1_Measuring the frequency and distribution of meiotic crossovers in homozygous barley inbred lines.pptx by Miriam Schreiber (529700)

“…We have previously shown that Hvmlh3 decreases both plant fertility and recombination by ~50%. …”

Confocal microscopic analysis of renal biopsy in active Class IV LN patient before IVMP pulse therapy. by Yi-Giien Tsai (514981)

“…(b) (c) right CD4⁺FoxP3⁺ and CD8⁺FoxP3⁺Treg cell expression significantly decreased before IVMP pulse therapy in renal tissue of Class IV LN (n = 50) FoxP3⁺ (brown); CD4⁺ or CD8⁺ (pink). …”

miRNA expression is altered in NSCs from diabetic pregnancy. by Sukanya Shyamasundar (420641)

“…The nucleus is counterstained with DAPI (blue). Scale bar: 50 µm. (C) miRNA expression analysis revealed decreased expression of miRNAs mmu-miR-200a, mmu-miR-200b, mmu-miR-466a-3p and mmu-miR-466d-3p in NSCs from diabetic pregnancy (open bars) when compared to the control (filled bars). …”

Bactericidal activity of serum pools from mice immunized with recombinant fHbp vaccines, or NOMV vaccines prepared from mutants of group B strain H44/76 with over-expressed or inac... by Rolando Pajon (166045)

“…Titers are means ± ranges of serum dilutions that gave 50% decreases in CFU/ml after one hr incubation with human complement measured in at least two assays. …”