Data_Sheet_1_Antiproliferative effect of boldine on neural progenitor cells and on glioblastoma cells.PDF by Enrique Jiménez-Madrona (16836648)

“…Analysis of the effect of boldine (25–600 μM) on different types of primary human GBM cells (GBM59, GBM96, and U87-MG) showed a concentration-dependent decrease in GBM cell growth. …”

Image2_Optimizing tacrolimus dosing in Hispanic renal transplant patients: insights from real-world data.JPEG by Athanasios Chamzas (19699780)

“…The estimated apparent clearance was 13.7 L/h for a typical patient weighing 70 kg and at 30% hematocrit, demonstrating a 40% decrease in clearance compared to other patient populations. …”

NHR-31 promotes expression of numerous genes encoding subunits of the vacuolar ATPase. by Annett Hahn-Windgassen (262120)

“…To avoid the larval lethality that occurs when <i>vha</i> subunits are disrupted very early in development, we treated worms with <i>nhr-31</i>, <i>vha-5</i>, <i>vha-8 and vha-12</i> RNAi beginning at the L3 stage of larval development. …”

Building Strain with Large Macrocycles and Using It To Tune the Thermal Half-Lives of Hydrazone Photochromes by Quan Li (157017)

“…Macrocyclization is used to build-up strain in such systems, and in general the reactivity and rates increase with the decrease in macrocycle size. To ascertain the effect of strain on recently reported bistable hydrazone photoswitches, we incorporated them into macrocycles having varying aliphatic linker lengths (<b>C3</b>–<b>C7</b>), and studied their switching behavior, and effect of macrocycle size on the thermal isomerization rate. …”

Oral Health Policy in Brazil: changes and ruptures during the period 2018-2021 by Lília Paula de Souza Santos (6146060)

“…Federal funding dropped in 2018 and 2019 (8.45%), followed by an increase in 2020 (59.53%) and decrease in 2021 (-5.18%). The study period was marked by economic and political crises aggravated by the COVID-19 pandemic. …”

Supplementary Material for: Use of Sotrovimab for COVID-19 in a patient with IGCCC Poor Prognosis testicular germ cell tumor by Nagasaka H. (16989984)

“…After obtaining fully informed consent, BEP therapy was continued from day 5, while sotrovimab (anti-COVID-19 drug) was administered. …”

Average rank of best RMSD result returned by PF²<i>fit</i>—SE(3) after reranking. by Radhakrishna Bettadapura (813776)

“…The figures in brackets denote the rank in the presence of noise at SNR = 1. We see a strong decrease in rank for the skeleton-secondary structure score with and without noise while the mutual information score remains predictable across the range of resolutions. …”

Building Strain with Large Macrocycles and Using It To Tune the Thermal Half-Lives of Hydrazone Photochromes by Quan Li (157017)

“…Macrocyclization is used to build-up strain in such systems, and in general the reactivity and rates increase with the decrease in macrocycle size. To ascertain the effect of strain on recently reported bistable hydrazone photoswitches, we incorporated them into macrocycles having varying aliphatic linker lengths (<b>C3</b>–<b>C7</b>), and studied their switching behavior, and effect of macrocycle size on the thermal isomerization rate. …”

Model predictions for the <i>in vitro</i> experiments of Ivanovic <i>et al</i>. by Ajit Akole (6555791)

“…<p>(A) At time zero, external pH (dashed line) begins a rapid decrease to pH 4.5. Internal pH (solid line) lags behind by as as much as ~1 minute but eventually equilibrates with the external pH after ~2 minutes. …”

Bifurcation and Stochastic Analysis of Network 1 with constitutive basal expression. by Philippe C. Faucon (603873)

“…With the addition of the constitutive expression we can see a further decrease in stabilities, specifically two-ON states are never stable. …”

Icaritin and lenvatinib treatment for unresectable localized progressive pancreatic cancer: a report of six cases by Xiaolong Liu (265696)

“…Partial responses were observed in cases 1 and 3, with some tumor shrinkage. Cases 4 and 5 showed limited relief following a slight decrease in tumor size. …”

Proton Transfer and Structure-Specific Fluorescence in Hydrogen Bond-Rich Protein Structures by Dorothea Pinotsi (1305144)

Building Strain with Large Macrocycles and Using It To Tune the Thermal Half-Lives of Hydrazone Photochromes by Quan Li (157017)

“…Macrocyclization is used to build-up strain in such systems, and in general the reactivity and rates increase with the decrease in macrocycle size. To ascertain the effect of strain on recently reported bistable hydrazone photoswitches, we incorporated them into macrocycles having varying aliphatic linker lengths (<b>C3</b>–<b>C7</b>), and studied their switching behavior, and effect of macrocycle size on the thermal isomerization rate. …”

Building Strain with Large Macrocycles and Using It To Tune the Thermal Half-Lives of Hydrazone Photochromes by Quan Li (157017)

“…Macrocyclization is used to build-up strain in such systems, and in general the reactivity and rates increase with the decrease in macrocycle size. To ascertain the effect of strain on recently reported bistable hydrazone photoswitches, we incorporated them into macrocycles having varying aliphatic linker lengths (<b>C3</b>–<b>C7</b>), and studied their switching behavior, and effect of macrocycle size on the thermal isomerization rate. …”

Isoenzyme activity in monitoring deterioration of Balfourodendron riedelianum seeds by Cristina Fernanda Schneider (5716772)

“…<div><p>ABSTRACT. In this study, we sought to identify efficient enzymes for use in monitoring the deterioration and loss of germination of Balfourodendron riedelianum (Engler) Engler seeds. …”

Energy Transfer on Demand: Photoswitch-Directed Behavior of Metal–Porphyrin Frameworks by Derek E. Williams (1653655)

“…We attribute the observed cyclic fluorescence behavior of the synthesized porphyrin–BPMTC array to activation of energy transfer (ET) pathways through BPMTC photoisomerization. …”

Isocorydine Inhibits Cell Proliferation in Hepatocellular Carcinoma Cell Lines by Inducing G2/M Cell Cycle Arrest and Apoptosis by Hefen Sun (163541)

“…In addition, isocorydine treatment led to a decrease in the percentage of CD133⁺ PLC/PRF/5 cells. …”

Supplementary Material for: Melatonin Reduces Hypoglycemia-Induced Neuronal Death in Rats by Kim J.H. (2867312)

“…In the present study, we hypothesized that exogenous melatonin may decrease hypoglycemia-induced neuronal death through the prevention of superoxide generation. …”

Building Strain with Large Macrocycles and Using It To Tune the Thermal Half-Lives of Hydrazone Photochromes by Quan Li (157017)

“…Macrocyclization is used to build-up strain in such systems, and in general the reactivity and rates increase with the decrease in macrocycle size. To ascertain the effect of strain on recently reported bistable hydrazone photoswitches, we incorporated them into macrocycles having varying aliphatic linker lengths (<b>C3</b>–<b>C7</b>), and studied their switching behavior, and effect of macrocycle size on the thermal isomerization rate. …”

P(O)H to P–OH Tautomerism: A Theoretical and Experimental Study by Benjamin G. Janesko (1441756)