Supplementary Material for: Effect of SOM230 (Pasireotide) on Corticotropic Cells: Action in Dogs with Cushing’s Disease by Castillo V. (4126174)

“…SOM230 (pasireotide) is a multiligand somatostatin (SRIF) analog able to bind to somatostatin receptor (SSTR) subtypes 1, 2, 3 and 5, and trigger antisecretory and antiproliferative signaling cascades. …”

Spatial Frequency Discrimination: Effects of Age, Reward, and Practice by Carlijn van den Boomen (3079293)

“…Moreover, thresholds decreased during the run, indicating that discrimination abilities improved. …”

Synthesis of Prepolymers of Poly(glycerol-<i>co</i>-diacids) Based on Sebacic and Succinic Acid Mixtures by Bruno Godinho (15361999)

“…All polycondensation reactions were performed at 150 °C until reaching a degree of polymerization of ≈55%, inferred by the water volume collected from a reactor. We concluded that the reaction time is correlated with the ratio of diacids used, that is, the increase in succinic acid is proportional to a decrease in the duration of the reaction. …”

Azocyclotin Binds CDK4 to Disrupt DNA Methylation in Zebrafish Epigenetic Transgenerational Inheritance by Aoxue Wang (275954)

“…ACT exposure induced a 38.03% decrease in global DNA methylation, as determined by 5-mC quantification. …”

Altering Pyrroloquinoline Quinone Nutritional Status Modulates Mitochondrial, Lipid, and Energy Metabolism in Rats by Kathryn Bauerly (213012)

“…Moreover, PQQ administration (i.p. at 4.5 mg/kg BW for 3 days) resulted in a greater than 2-fold decrease in plasma triglycerides during a 6-hour fast than saline administration in a rat model of type 2 diabetes. …”

DataSheet_1_Crosstalk Between Pyroptosis and Apoptosis in Hepatitis C Virus-induced Cell Death.pdf by Hannah L. Wallace (12082871)

“…In a model employing a cell culture-adapted strain of JFH-1 HCV and Huh-7.5 hepatocyte-like cells, we found that pyroptosis occurred earlier than did apoptosis during infection. …”

DataSheet1_Systematic Analysis of mRNAs and ncRNAs in BMSCs of Senile Osteoporosis Patients.docx by Yiyun Geng (11856116)

“…Interestingly, circRNA008876-miR-150-5p-mRNA was the sole predicted circRNA-miRNA-mRNA network. …”

Image_3_Trends in Incidence and Mortality of Waldenström Macroglobulinemia: A Population-Based Study.TIF by Xuejiao Yin (5132441)

“…</p><p>Results: The incidence of WM showed an initial rapid increase from 1980 to 1993 {annual percentage change (APC), 14.1% [95% confidence interval (CI), 10 to 18.4%]}, whereas it began to stabilize from 1993 to 2016 [APC, 0.5% (95% CI, −0.3 to 1.3%)]. The WM IBM trend followed a similar pattern, with a decrease occurring around 1994. …”

Image_4_Trends in Incidence and Mortality of Waldenström Macroglobulinemia: A Population-Based Study.TIF by Xuejiao Yin (5132441)

“…</p><p>Results: The incidence of WM showed an initial rapid increase from 1980 to 1993 {annual percentage change (APC), 14.1% [95% confidence interval (CI), 10 to 18.4%]}, whereas it began to stabilize from 1993 to 2016 [APC, 0.5% (95% CI, −0.3 to 1.3%)]. The WM IBM trend followed a similar pattern, with a decrease occurring around 1994. …”

Supplementary Material for: Personalized Approach of Severe Eosinophilic Asthma Patients Treated with Mepolizumab and Benralizumab by Bergantini L. (9186272)

“…<b><i>Background:</i></b> New anti-IL-5 antibodies, mepolizumab and benralizumab, have recently been approved for severe asthma, sharing the same inclusion criteria. …”

Azocyclotin Binds CDK4 to Disrupt DNA Methylation in Zebrafish Epigenetic Transgenerational Inheritance by Aoxue Wang (275954)

“…ACT exposure induced a 38.03% decrease in global DNA methylation, as determined by 5-mC quantification. …”

Presentation_1_Antitumoral Action of Resveratrol Through Adenosinergic Signaling in C6 Glioma Cells.PDF by Alejandro Sánchez-Melgar (3950141)

“…The adenosine level mainly depends on two enzymatic activities: 5′-nucleotidase (5′NT or CD73) that synthesizes adenosine from AMP, and adenosine deaminase (ADA) that converts adenosine into inosine. …”

Table_1_Protein-A immunoadsorption combined with immunosuppressive treatment in refractory primary Sjögren’s syndrome coexisting with NMOSD: a case report and literature review.pdf... by Wei Fan (109074)

“…During the follow-up period, prednisolone was gradually tapered to a maintenance dose of 5-10 mg/day, whereas mycophenolate mofetil (MMF) was maintained at 1.0-1.5 g/day. …”

Data_Sheet_2_Predictors of Permanent Pacemaker Implantation in Patients After Transcatheter Aortic Valve Replacement in a Chinese Population.DOCX by Jiaqi Zhang (412762)

“…TAVR induced several cardiac electrical changes such as increased R wave and T wave changes in lead V5. The main independent predictors of PPM implantation were new-onset left bundle branch block (LBBB) (coef: 3.211, 95% CI: 0.899–7.467, p = 0.004) and lead I T wave elevation (coef: 11.081, 95% CI: 1.632–28.083, p = 0.016).…”

Supplementary Material for: Fifteen years of neonatal Therapeutic Hypothermia: clinical trends show unchanged post-rewarming outcomes despite reduction in HIE severity by vanOldenmark B.O. (19737751)

“…Inotropic support decreased (p=0.007), and use of invasive mechanical ventilation decreased over the last five years. …”

A reconnaissance provenance study of Triassic–Jurassic clastic rocks of the Russian Barents Sea by Andrey K. Khudoley (7352681)

“…The number of Palaeoproterozoic and Archean grains is very small and becomes significant only in a few Jurassic samples. ε_Nd(t) values gradually decrease from −1.5 to +2.5 in Lower Triassic rocks, to −2.0 to −8.2 in Jurassic rocks, suggesting an increasing influence of ancient metamorphic basement erosion in the younger Jurassic rocks. …”

Image_2_Trends in Incidence and Mortality of Waldenström Macroglobulinemia: A Population-Based Study.TIF by Xuejiao Yin (5132441)

“…</p><p>Results: The incidence of WM showed an initial rapid increase from 1980 to 1993 {annual percentage change (APC), 14.1% [95% confidence interval (CI), 10 to 18.4%]}, whereas it began to stabilize from 1993 to 2016 [APC, 0.5% (95% CI, −0.3 to 1.3%)]. The WM IBM trend followed a similar pattern, with a decrease occurring around 1994. …”

<strong>Contrasting exogenous and endogenous soil microbial carbon use efficiencies under global changes</strong> by Andong Cai (5237024)

“…Invasive plants significantly decreased microbial CUEex by 11.5%. Global change enhanced the microbial growth rate by 6.5%; however, when combined with added exogenous carbon there was a decrease of 3.2%. …”

Table_1_Chronic constant light exposure aggravates high fat diet-induced renal injury in rats.docx by Lin Xing (7384631)

“…Then, we demonstrated that BMAL1 bound directly to the promoters of PHD1 in mouse podocyte clone 5 cell line (MPC5) by ChIP assays. …”

Data_Sheet_1_N6-Methyladenine in Eukaryotic DNA: Tissue Distribution, Early Embryo Development, and Neuronal Toxicity.PDF by Sara B. Fernandes (10860612)

“…The prevailing dogma states that DNA methylation in eukaryotes occurs essentially through 5-methylcytosine (5mC) but recently adenine methylation was also found to be present in eukaryotes. …”