Design, Synthesis, and Biological Evaluation of Covalent Inhibitors of Focal Adhesion Kinase (FAK) against Human Malignant Glioblastoma by Bo Li (112195)

“…Herein, we report the structure-guided development of a series of covalent inhibitors of FAK. These new compounds displayed highly potent inhibitory potency against FAK enzymatic activity with IC₅₀ values in the nanomolar range. …”

The productivity of a research unit as a function of the funding <i>x</i>. by Miguel Navascués (164739)

Presentation1_The impact of Climate Change on extreme winds over northern Europe according to CMIP6.pdf by Xiaoli Guo Larsén (12502987)

“…We obtain the possible effect of climate change through the comparison of the extreme wind parameters, including the 50-year wind and the 95%-percentile of the wind speed, and the change in turbine class at 50 m, 100 m and 200 m, between a near future period (2020–2049) and the historic period (1980–2009). …”

Synthesis and Biological Evaluation of New Chalcogen Semicarbazone (<i>S</i>, <i>Se</i>) and Their Azole Derivatives against Chagas Disease by Mercedes Rubio-Hernández (20036142)

“…Seleno-compounds demonstrated enhanced activity and selenazoles showed a decrease in selenium-associated toxicity. Compound 4-methyl-2-(2-(1-(3-nitrophenyl)­ethylidene)­hydrazineyl)-1,3-selenazole (<i><b>Se</b></i><b>2h</b>) emerged as a promising candidate, and its binding to cruzain was investigated. …”

Synthesis and Biological Evaluation of New Chalcogen Semicarbazone (<i>S</i>, <i>Se</i>) and Their Azole Derivatives against Chagas Disease by Mercedes Rubio-Hernández (20036142)

“…Seleno-compounds demonstrated enhanced activity and selenazoles showed a decrease in selenium-associated toxicity. Compound 4-methyl-2-(2-(1-(3-nitrophenyl)­ethylidene)­hydrazineyl)-1,3-selenazole (<i><b>Se</b></i><b>2h</b>) emerged as a promising candidate, and its binding to cruzain was investigated. …”

Image_1_Extracellular Vesicles Carry lncRNA SNHG16 to Promote Metastasis of Breast Cancer Cells via the miR-892b/PPAPDC1A Axis.TIFF by Wenfei Xia (5055482)

High blood glucose levels in rats after exposure to STZ. by Shatw Khalid Ali (13020885)

S1 Dataset - by Anotida R. Hove (20513536)

“…The mean age of the study participants was 26.1 (±5.9) years. 89% of the pregnant women did not meet the WHO recommendations of 150 minutes of moderate-intensity PA. …”

EBBS frequencies, N = 517. by Anotida R. Hove (20513536)

“…The mean age of the study participants was 26.1 (±5.9) years. 89% of the pregnant women did not meet the WHO recommendations of 150 minutes of moderate-intensity PA. …”

EBBS summative indices, N = 517. by Anotida R. Hove (20513536)

“…The mean age of the study participants was 26.1 (±5.9) years. 89% of the pregnant women did not meet the WHO recommendations of 150 minutes of moderate-intensity PA. …”

Exercise Habits, N = 517. by Anotida R. Hove (20513536)

“…The mean age of the study participants was 26.1 (±5.9) years. 89% of the pregnant women did not meet the WHO recommendations of 150 minutes of moderate-intensity PA. …”

Adjusted odds ratios. by Anotida R. Hove (20513536)

“…The mean age of the study participants was 26.1 (±5.9) years. 89% of the pregnant women did not meet the WHO recommendations of 150 minutes of moderate-intensity PA. …”

Obstetric and health characteristics, N = 517. by Anotida R. Hove (20513536)

“…The mean age of the study participants was 26.1 (±5.9) years. 89% of the pregnant women did not meet the WHO recommendations of 150 minutes of moderate-intensity PA. …”

Physical activity summative indices, N = 517. by Anotida R. Hove (20513536)

“…The mean age of the study participants was 26.1 (±5.9) years. 89% of the pregnant women did not meet the WHO recommendations of 150 minutes of moderate-intensity PA. …”

Sociodemographic characteristics, N = 517. by Anotida R. Hove (20513536)

“…The mean age of the study participants was 26.1 (±5.9) years. 89% of the pregnant women did not meet the WHO recommendations of 150 minutes of moderate-intensity PA. …”

Potent 5‑Cyano-6-phenyl-pyrimidin-Based Derivatives Targeting DCN1–UBE2M Interaction by Wenjuan Zhou (115285)

“…After finding a novel inhibitor <b>DC-1</b> with IC₅₀ = 1.2 μM, we performed a series of chemical optimizations, which finally led to the discovery of a potent thiazole containing 5-cyano-6-phenylpyrimidin-based inhibitor <b>DC-2</b> (IC₅₀ = 15 nM). …”

Long-term outcomes of macrovascular diseases and metabolic indicators of bariatric surgery for severe obesity type 2 diabetes patients with a meta-analysis by Guoli Yan (4591687)

“…Fixed-effects and random-effects meta-analyses were performed to pool the relative risks (RRs), hazard ratios (HRs) and weighted mean difference (WMD). Publication bias and heterogeneity were examined. …”

The effects of metformin, donepezil, insulin glargine, and glibenclamide on brain biomarkers: Amyloid β 42, nitric oxide, acetylcholinesterase, malondialdehyde, β secretase, and pM... by Shatw Khalid Ali (13020885)

GSH evokes increase in the extracellular GABA levels in chick retinal tissue and in mixed neuronal-glial cells in culture. by Hercules R. Freitas (3174633)

“…<p>GSH treatment evokes GABA release in chick retinal tissue or in cells in culture (A) Extracellular GABA levels were measured in E11 avian retina upon incubation with 1–5mM GSH for 10 min. Values are means ± SD from two independent experiments (ANOVA-Tukey *<i>p</i> < 0.01 vs. control, n ≥ 4). …”

List of antibodies used in this study. by Riya Ghosh (17116962)

“…CAY10585, a HIF1α-inhibitor, decreased the DENV2 infection by increasing <i>IFN-A/B</i> and <i>IRF-3/7/9</i> expression. …”