Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…Here, we synthesized a newseries of <i>mono</i>- and <i>bis</i>(dimethylpyrazolyl)-<i>s</i>-triazine derivatives. …”

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…Here, we synthesized a newseries of <i>mono</i>- and <i>bis</i>(dimethylpyrazolyl)-<i>s</i>-triazine derivatives. …”

Sustained expression of radmis results in decreased cell proliferation and increased cell-cycle exit of NSPCs. by Takahito Yumoto (481671)

miR-200c decreases KLOTHO expression in HK-2 cells by translational repression. by Kenichi Morii (6843554)

YTX treatment decreases tumour development in the B16F10 melanoma mouse model. by Araceli Tobío (3545306)

Rabankyrin-5 Overexpression Increases, whereas Knock-Down Decreases Fluid-Phase Uptake, Specifically by Carsten Schnatwinkel (48)

Secreted Human Adipose Leptin Decreases Mitochondrial Respiration in HCT116 Colon Cancer Cells by Einav Yehuda-Shnaidman (461266)

“…Our results show that conditioned media from obese (vs. non-obese) subjects decreased basal (40%, <i>p<0.05</i>) and maximal (50%, <i>p<0.05</i>) OCR and gene expression of mitochondrial proteins and Bax without affecting cell viability or expression of glycolytic enzymes. …”

S-glutathionylation catalyst diamide also decreases ROS release from permeabilized skeletal muscle mitochondria. by Robert M. Gill (4854028)

“…The final concentration of pyruvate, 2-oxoglutarate, succinate, or palmitoyl-carnitine was 50 μM. n = 4, mean±SEM. (B) The decrease in mitochondrial ROS release correlates with an increase in overall protein S-glutathionylation. …”

Increased naive and transitional but decreased memory blood B cells in active chronic sarcoidosis patients. by Anne Saussine (310501)

Methylation levels of the <i>Ucp1</i> promoter decreased following genistein (GEN) treatment. by Noriko Sato (201880)

Imatinib induces the differentiation of human normal erythroblasts and decreases cell surface expression of c-Kit. by Diane D'allard (405441)

TBEV-induced translational arrest results in the decreased protein levels of GAPDH, HPRT1, and viperin. by Martin Selinger (3195987)

Gene ontology biological processes overrepresented among genes exhibiting decreased expression in human psoriasis. by William R. Swindell (175427)

“…<p>A total of 3540 transcripts were identified as significantly decreased in psoriatic plaques obtained from human patients relative to normal skin obtained from control subjects (FDR-adjusted P<0.05 and log₂-transformed fold-change less than -0.50). …”

Excision of HIF1α decreases viral reactivation from latency in infected splenocytes in vivo. by Darlah M. López-Rodríguez (8098544)

Loss of ALS2 results in decreased levels of the lysosome-dependent degradation of LC3 in fibroblasts. by Shinji Hadano (251529)

“…Fibroblasts from wild-type (WT) and <i>Als2</i>^−/− mice were either left unstarved (0 hr) (upper) or starved for 6 hr (lower). It is notable that a 6 hr of starvation leads to decreased levels of the LC3- and p62-immunoreactive signals in WT cells, but not in <i>Als2</i>^−/− cells. …”

Genkwanin exerts anti-inflammatory effects mainly through decreasing miR-101 production. by Yuan Gao (159945)

PLD1 inhibition decreases the c-Myc-dependent dNTP biosynthetic transcriptional program. by Harry E. Taylor (596259)

The gradual loss of the IFN-γ antiviral effect is accompanied by decreased STAT1 phosphorylation in BMMs. by Yong Shen (284972)

siATF2 treatment decreases γ-globin gene expression in K562 cells. by Li Liu (75607)

Klotho transfection reduced IC50 of both cell lines and inhibited Akt signal pathway. by Yan Wang (15435)

“…<b>C</b>: MTT assay showed a great decrease in IC50 of klotho transfected cells. …”