Effects of 20 mg·kg⁻¹ salidroside on apoptosis in contusion-injured mice. by Szu-Fu Chen (306048)

“…Bar graph of densitometric analysis of bands showing a significant decrease of (<b>D</b>) cleaved caspase-3 (<b>E</b>) cytosolic CytC and (<b>F</b>) cytosolic Smac/DIABLO protein levels in the ipsilateral hemisphere of SALD-20 treated mice at 1 and 3 days post-injury, compared with vehicle-treated mice. …”

Validation of model predictions of growth during infusion of hypertrophic agonists with and without receptor blockers. by Johane H. Bracamonte (12883844)

“…<p>a) Boxplot shows the mean, 50% confidence interval, and 90% confidence interval for predicted normalized growth in 1000 MC simulations of ISO infusion with the calibrated network. …”

Topographic map of study area in interior Alaska by Dana R Nossov (557153)

“…On average, fire caused a five-fold decrease in mean surface organic layer thickness, a doubling of water storage in the active layer, a doubling of thaw depth, an increase in soil temperature at the surface (−0.6 to +2.1 ° C) and at 1 m depth (−1.7 to +0.4 ° C), and a two-fold increase in net soil heat input. …”

LEF-1 independently regulates <i>TYR</i> expression. by Xueping Wang (509099)

“…Each value shown was the mean ± SD of three replicates from a single assay. …”

Data_Sheet_1_Dynamics of the Type I Interferon Response During Immunosuppressive Therapy in Rheumatoid Arthritis.pdf by Tamarah D. de Jong (6628217)

“…Between T4 and T13, however, IRG expression in the COBRA-light-treated group displayed a significant increase, whereas it remained stable or decreased even further in most COBRA-treated patients (comparison of mean fold changes, p = 0.011). …”

Influence of UGT2B10 Genotype on Urinary Excretion of 4‑(Methylnitrosamino)-1-(3-pyridyl)-1-butanol-<i>N-</i>glucuronide by African American Smokers by Sharon E. Murphy (272512)

“…In summary, the high prevalence of a <i>UGT2B10</i> splice variant among African Americans results in lower NNAL-<i>N</i>-glucuronidation but only a small decrease in total NNAL glucuronidation. …”

E protein residues critical for neutralization by bnAbs. by Jay Lubow (772012)

“…<p>(Left panel) Bar graphs show the mean IC50 fold change against DENV2 16681 reporter virus particles encoding E protein variants relative to wild type (WT) DENV2 for antibodies <b>(A)</b> F09.S05, <b>(B)</b> F05.S03, <b>(C)</b> J9, <b>(D)</b> F25.S02, and <b>(E)</b> EDE1-C10. …”

Climatic factors driving vegetation declines in the 2005 and 2010 Amazon droughts by Wenqian Zhao (3937202)

“…The results showed that (i) in the Amazon vegetation greenness responded to precipitation, radiation and temperature, with apparent time lags for most averaging interval periods associated with vegetation index responses of 0–4, 0–9 and 0–6 months, respectively; (ii) on average, the three climatic factors without time lags explained 27.28±21.73% (mean±1 SD) of vegetation index variation in the Amazon basin, and this value increased by 12.22% and reached 39.50±27.85% when time lags were considered; (iii) vegetation greenness in this region in non-drought years was primarily affected by precipitation and shortwave radiation, and these two factors altogether accounted for 93.47% of the total explanation; and (iv) in the common epicenter of the two droughts, pixels with a significant variation in precipitation, radiation and temperature accounted for 36.68%, 40.07% and 10.40%, respectively, of all pixels showing a significant decrease in vegetation index in 2005, and 15.69%, 2.01% and 45.25% in 2010, respectively. …”

Data_Sheet_1_Inhibitory Effects of Dietary N-Glycans From Bovine Lactoferrin on Toll-Like Receptor 8; Comparing Efficacy With Chloroquine.PDF by Susana Figueroa-Lozano (8825519)

“…The inhibition of TLR-8 in MoDCs resulted in a significant decrease of IL-6 when cells were treated with the unmodified (0.5-fold, p < 0.0001), partially demannosylated (0.3-fold, p < 0.0001) and partially desialylated (0.4-fold, p < 0.0001) N-glycans. …”

Supplementary Material for: TRENDS IN HOSPITAL DISCHARGES WITH PRIMARY DIAGNOSIS OF CEREBRAL VENOUS THROMBOSIS BY AGE AND SEX IN SPAIN by figshare admin karger (2628495)

“…Time series analysis showed a proportional decrease in younger women (p < 0.001) and a rising relative burden in older men (p < 0.001). …”

TF function predicted from regulatory parameters <i>α</i> and <i>β</i>. by Md Zulfikar Ali (11965544)

“…Black contours mark FC_max = 1 and subsequent contours represent 100–fold increase or decrease in FC_max. The observed regulation from a TF depends on promoter strength. …”

The effect of hydroxychloroquine on lupus erythematosus-like skin lesions in MRL/lpr mice by Tatsuya Shimomatsu (1545943)

“…The average number of mast cells was 81, 50, and 12 (magnification, ×100), the mortality rate was 24%, 8%, and 9% and the mean body weight gain was 4.6 g, 8.0 g and 5.1 g, respectively.…”

Acute TTBK1 inhibition reduces tau phosphorylation at disease relevant sites <i>in vivo</i>. by Gregory M. Dillon (8681430)

“…(A) At the highest dose tested (75mg/kg), there was a significant decrease in tau phosphorylation at several sites when quantified by immunoblotting (S422, AT180, S396, and AT8). …”

TBr inhibited cell proliferation in leukemia cell lines. by Anup S. Pathania (657368)

“…<p>(A–B) Cell proliferation assay. Cells were treated with 1, 10, 30, 50 and 100 µM concentrations of TBr for 24 and 48 h. …”

Determination of mitochondrial temperature in intact human cells. by Dominique Chrétien (217681)

“…Graphic drawings, means, and standard deviations are from values accessible in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.2003992#pbio.2003992.s009" target="_blank">S1 Data</a>. …”

Effects of adenosine receptor-specific antagonists on responses to hypoxia at E9.5 and E12.5. by Daniela L. Buscariollo (140729)

“…At both ages, heart rates were not affected by SCH-58261 treatment (A and B). In contrast, at both ages DPCPX elevated heart rates above vehicle levels in normoxic conditions and inhibited hypoxia-mediated heart rate decrease below baseline (A and B). …”

Transmembrane signaling in cell-derived plasma membrane vesicles. by Luigino Grasso (208932)

“…(D) The FRET signal increases with the concentration of agonist APEC added to the bulk solution (concentrations indicated above the bars in nM). (E) A dose-dependent increase of the FRET yields <i>EC₅₀</i> = 100±11 nM; shown are averages and standard deviations of the mean of nine titration experiments each performed on different, individual vesicles.…”

One of the two daughter cells often survives the chromosome XII missegregation event, even in the absence of Rad52. by Oliver Quevedo (183588)

“…Examples of colonies of different sizes are indicated (“b” and “s” point to big and small colonies respectively). Underneath, a table sums up the main features of the growing colonies, including: an estimate of viable cells (actual colony number divided by cells counted before plating, mean ± SEM, n = 3), percentage of slow-growing colonies (mean ± SEM, n = 3) and colony diameter of each type (mean ± SD, n>30). …”

Analysis of the relation between ribosomal protein genes transcription and pre-mRNA processing during osmotic stress. by Elena Garre (5136275)

“…The data set series for intron-containing RP genes refers to their respective 0 time on a logarithm scale. A relative repression (stress/non-stress ratio, on the log₂ scale) is shown in green (saturated green indicates a decrease of at least 6-fold) and relative induction is depicted red (saturated red indicates an increase of at least 6-fold). …”

DataSheet_1_Improving in-season wheat yield prediction using remote sensing and additional agronomic traits as predictors.docx by Adrian Gracia-Romero (11046789)

“…This was particularly evident when NDVI saturates (with yields above 8 t ha^-1) with models including NDVI and days to heading providing a 50% increase in the prediction accuracy and a 10% decrease in the root mean square error. …”