The knock-down of DBP5, GLE1 or IPPK affects the different subsets of cytoplasmic mRNA expressions. by Masumi Okamura (5204690)

“…<p>(A) The Venn diagram represents cytoplasmic transcripts reduced at least 1.5-fold in DBP5, GLE1 or IPPK knock-down cells. …”

Summary of the time-course when the first significant changes were measured (relative to baseline values) in ONH parameters, ALCS pore geometry, and RNFLT in all EG eyes. by Kevin M. Ivers (778159)

“…A progressive decrease in RNFLT was measured throughout the course of the study in all EG eyes except OHT-67 (which also showed no significant change in ALCS pore geometry, mean RoC, and RNFLT). …”

Variable importance for the random forest model on adoption of non-bank payment methods. by Santiago Carbo-Valverde (9575368)

“…The left-hand side graph shows the Top 20 features by Mean Decrease in Accuracy. The centered graph shows the Top 20 features by Mean Decrease in Gini. …”

PIK3CA promoter activity in SKOV3 (p53 deficient) tumor xenograft model after cisplatin treatment. by Snehal M. Gaikwad (279479)

“…Mouse from control and treated group exhibited specific [Fig. 4a3 (pre-treatment)] signals which did not decrease even after two treatments of cisplatin [Fig. 4a3 (post-treatment)].…”

Validation of RNA sequencing by RT-qPCR. by Olga Østrup (408062)

“…Grey bars named Bc qPCR show fold changes between blastocyst/2-cell stages and demonstrate the tendency towards continuous decrease in the amount of these transcripts. …”

Effect of BM pretreatment on P-gp level. by Rajbir Singh (451210)

“…BM treatment decreases the MDR1 level in intestine. Fold changes in mRNA level are derived after normalizing with GAPDH mRNA level used as internal loading control (n = 3 in each group) and are indicated by numbers. …”

Summary of the in vitro and in vivo characterization of PCNA mutants. by Yearit Fridman (240019)

“…</p>c<p>Fold increase or decrease in the PCNA-partner interaction affinities measured as the generation time of the Y2H strains grown in liquid selective media lacking histidine, relative to cells expressing WT PCNA (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1000507#pbio.1000507.s004" target="_blank">Figures S4</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1000507#s4" target="_blank">Materials and Methods</a>).…”

Metabolic changes associated with AN5568 treatment. by Pieter C. Steketee (466154)

“…WT; wild type untreated, AN5568; wildtype treated for six hours at 10x EC₅₀. C) A schematic to show the metabolites involved in methyltransferase reactions. …”

Summary of the TAFV challenge study results through 15 days post challenge (study day 70–85). by Kelly L. Warfield (130405)

“…<i>0°F over baseline; Temp drop was defined as a temperature more than 3</i>.<i>0°F below baseline; mild rash = focal areas of petechiae covering less than 10% of skin; moderate rash = areas of petechiae covering between 10% and 40% of the skin; severe rash = areas of petechiae or ecchymosis covering more than 40% of the skin</i></p><p><i>↑</i>, <i>2- to 3-fold increase</i></p><p><i>↑↑</i>, <i>4- to 5-fold increase</i></p><p><i>↑↑↑</i>, <i>> 5-fold increase</i></p><p><i>↓</i>, <i>2- to 3-fold decrease</i></p><p><i>WL</i>: <i>weight loss was the percentage compared to the weight at study initiation; BUN</i>: <i>blood urea nitrogen; ALT</i>: <i>alanine aminotransferase; AST</i>: <i>aspartate aminotransferase; ALP</i>: <i>alkaline phosphatase; ALB</i>: <i>albumin</i>, <i>Glu</i>: <i>glucose</i>, <i>Cre</i>: <i>creatinine</i>, <i>WBC</i>: <i>white blood cells; Plt</i>: <i>platelet</i>, <i>Lym</i>: <i>lymphocyte</i>.…”

FACS data of NMCC following reperfusion. by Sreejit Parameswaran (671449)

“…The fold level increase or decrease of protein expressing NMCC in each quadrant has been represented. …”

Time series of the number of uninfected cells for simulations in Fig 5. by T. J. Sego (9904909)

“…<p>Logarithmic multidimensional parameter sweep performed by running 10 simulation replicas increasing and decreasing the baseline parameter values 10-fold and 100-fold for all parameter sets and replicas in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008451#pcbi.1008451.g005" target="_blank">Fig 5</a>. …”

Time series of the number of virus releasing cells for simulations in Fig 5. by T. J. Sego (9904909)

“…<p>Logarithmic multidimensional parameter sweep performed by running 10 simulation replicas increasing and decreasing the baseline parameter values 10-fold and 100-fold for all parameter sets and replicas in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008451#pcbi.1008451.g005" target="_blank">Fig 5</a>. …”

Time series of the immune response state variable <i>S</i> for simulations in Fig 5. by T. J. Sego (9904909)

“…<p>Logarithmic multidimensional parameter sweep performed by running 10 simulation replicas increasing and decreasing the baseline parameter values 10-fold and 100-fold for all parameter sets and replicas in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008451#pcbi.1008451.g005" target="_blank">Fig 5</a>. …”

Time series of the number of immune cells for simulations in Fig 5. by T. J. Sego (9904909)

“…<p>Logarithmic multidimensional parameter sweep performed by running 10 simulation replicas increasing and decreasing the baseline parameter values 10-fold and 100-fold for all parameter sets and replicas in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008451#pcbi.1008451.g005" target="_blank">Fig 5</a>. …”

Recovery of <i>L. major</i> parasites following exposure to hydrogen peroxide treatment. by Fiona M. Sansom (253371)

High levels of RhoG activity in HPV-18 transformed cells is hDlg and HPV -dependent. by Vanitha Krishna Subbaiah (183285)

“…HeLa cells were transfected with control siRNA (Luc) siRNA to E6/E7 (i) or siRNA to hDlg-1 (ii) and were then analysed for the levels of hDlg, SGEF, and p53 expression after 72 hrs in the insoluble and soluble compartments of the cell. α-Actinin was used as a loading control. Note the marked increase in hDlg levels in the soluble fraction with concomitant decrease in the insoluble fraction following E6/E7 removal, which is also accompanied by a decrease in SGEF levels in this compartment and a similar loss of SGEF in the insoluble compartment is seen following siRNA ablation of hDlg-1 expression. …”

Retinal morphology and function is damaged in TALEN <i>clcc1</i>-KO zebrafish. by Lin Li (28817)

“…<i>clcc1</i> KO embryos show destruction of the rod photoreceptor layer (b) compared with WT (a). While somewhat better preserved than in the morpholino <i>clcc1</i> knockdown embryos, cone photoreceptors and the other retinal layers also appear decreased. …”

Approaches to Improve the Oral Bioavailability and Effects of Novel Anticancer Drugs Berberine and Betulinic Acid by Chandraiah Godugu (101721)

“…Molecular studies done on excised tumor (A549) tissue suggested that BBR in SD form resulted in a significant decrease in the survivin, Bcl-2, cyclin D1, MMP-9, HIF-1α, VEGF and CD31 expressions. …”

Ran knock down by RNAi results in abnormal neurite morphology in mouse neurons. by Katharine J. Sepp (50335)

“…Equal loadings of total protein shown by tubulin signal demonstrates a decrease in the amount of Ran by about 50% in the presence of <i>Ran</i> Rnai-2 and when the two constructs are combined. …”

CD97 expression in GBM is inversely related to survival. by Michael Safaee (301989)

“…Up-regulated tumors were defined as those with a greater than two-fold increase in CD97 transcript, while those with a greater than two-fold decrease were classified as down-regulated. …”