SOX9 Regulates Multiple Genes in Chondrocytes, Including Genes Encoding ECM Proteins, ECM Modification Enzymes, Receptors, and Transporters by Chun-do Oh (250561)

“…For RNA-Seq, the RNA expression profile of primary <i>Sox9^flox/flox</i> mouse chondrocytes infected with Ad-CMV-<i>Cre</i> was compared with that of the same cells infected with a control adenovirus. Analysis of RNA-Seq data indicated that, when the levels of <i>Sox9</i> mRNA were decreased more than 8-fold by infection with Ad-CMV-<i>Cre</i>, 196 genes showed a decrease in expression of at least 4-fold. …”

Production of infectious HCV in cell culture. by Deborah L. Diamond (255229)

“…The reason for these decreases is unclear, but may be related to a decrease in the number of cells capable of producing high levels of virus.…”

MAb 1340 inhibits function of the alternative complement system. by Diana Pauly (170378)

“…The <i>E. coli</i> lysis assay showed comparable inhibitory results with the hemolysis assay. MAb A235 showed a decrease in viable <i>E. coli</i> at concentrations above 1 µg/mL. …”

DataSheet_1_Polarized distribution of extracellular nucleotides promotes gravity-directed polarization of development in spores of Ceratopteris richardii.docx by Ashley E. Cannon (8395479)

“…The [eATP] along the bottom of the spore averaged 7-fold higher than the concentration at the top. All treatments that disrupted eATP signaling resulted in a statistically significant decrease in the gravity response. …”

Highly Energetic Materials-Hosted 3D Inverse Opal-like Porous Carbon: Stabilization/Desensitization of Explosives by Moo-Kwang Shin (1430449)

“…Such sensitivities could be controlled by adjusting the surface area or (in)­organic additives; however, increased stability leads to a decrease in the explosives’ performance. Here, high-energy-density molecules hosted in inverse opal-like porous carbon (IOC) nanocomposites demonstrate the mechanical stabilization and desensitization of RDX and HMX inside the carbon nanostructure using host–guest chemistry techniques. …”

Variable importance. by Carl Delfin (6707984)

“…<p>Variable importance measured as the scaled mean decrease in accuracy of each variable in the Baseline and Extended model. …”

Data_Sheet_1_Finger-specific effects of age on tapping speed and motor fatigability.docx by Caroline Heimhofer (19735888)

“…Finger tapping at maximal speed results in a rapid decrease in movement speed, which is a measure of motor fatigability.…”

Supplementar material of the manuscript  The Effects of Lipoic Acid on Yolk Nutrient Utilization, Energy Metabolism, and Redox Balance over Time in <em>Artemia</em> sp.  by Juan Rafael Buitrago Ramírez (6244172)

“…ETS activity was positively regulated by the addition of LA, with the most significant effects at concentrations of 5.0 and 10.0 µM at 12 and 24 h. For ETS activity, treatments with LA presented the highest values at 24 h, a period when ROS production decreased significantly, for the treatment with 10.0 µM. …”

Mitochondrial transcriptome analysis of the <i>FASTKDs</i>-KO cells by RNA-seq. by Akira Ohkubo (2955393)

“…Results are mean±SD *P<0.05, **P<0.01 (Wald test). (<b>B-C</b>) A complete map of mtRNA abundance and mean (log₂ fold change [KO_mean/Ctrl_mean]) determined by RNA-seq coverage from control, <i>FASTKD3</i>-sKO, <i>FASTKD4</i>-sKO, <i>FASTKD5</i>-sKO, <i>FASTKD3&4</i>-dKO, and <i>FASTKD4&5</i>-dKO cells (n = 3). …”

Control vector analysis for noise reduction. by Kyung H. Kim (188027)

“…<p>The noise level of a concentration (variance divided by mean squared) is aimed to be reduced while its mean level does not change. …”

Cross Platform Standardisation of an Experimental Pipeline for Use in the Identification of Dysregulated Human Circulating MiRNAs by Helena Kelly (794018)

“…However, upon enrichment for the small RNA population and subsequent analysis of miR-320a using RT-qPCR, its dysregulation in breast cancer patients was more pronounced with an 8.89-fold decrease in miR-320a expression. …”

Sediment Contaminated with the Azo Dye Disperse Yellow 7 Alters Cellular Stress- and Androgen-Related Transcription in <i>Silurana tropicalis</i> Larvae by Justine Mathieu-Denoncourt (1839595)

“…The same treatment also altered the expression of two androgen-related genes: decreased <i>ar</i> (2-fold) and increased <i>srd5a2</i> (2.6-fold). …”

Non-invasive imaging of PIK3CA promoter modulation in tumor xenografts of living mice after cisplatin treatment. by Snehal M. Gaikwad (279479)

“…(Day 1 represents the day prior to treatment). 3a2. Graphical representation of fold-changes in the bioluminescence signals. …”

Sediment Contaminated with the Azo Dye Disperse Yellow 7 Alters Cellular Stress- and Androgen-Related Transcription in <i>Silurana tropicalis</i> Larvae by Justine Mathieu-Denoncourt (1839595)

“…The same treatment also altered the expression of two androgen-related genes: decreased <i>ar</i> (2-fold) and increased <i>srd5a2</i> (2.6-fold). …”

DELTA-1/NOTCH signaling in the caudal spinal cord of chick embryos. by Barbara Hämmerle (36261)

“…<p>A–A′. Confocal projection over 50 µm from a dorsal aspect of the prospective spinal cord at the level of the 12^th and 13^th somites counted from rostral of a HH13 chick embryo that was electroporated with NICD at stage HH10 when that region was part of the PNTZ. …”

PDGFR inhibition blocked ISV formation and extension. by Katie M. Wiens (363766)

“…Inhibition of PDGFRs resulted in a decrease in the number of angiogenic sprouts (asterisks in A) in the tail at 24 hpf (B) and a decrease in the number of complete ISVs (arrowheads in A) at 48 hpf (A and C) and 72 hpf (A and D). …”

Supplementary Materials by Johnson C.Y. Pang (10854111)

“…Data were pooled using a random-effects model and sensitivity analysis if heterogenicity was high (<em>I</em>2≥50%). …”

Antiviral therapies and viral strain affect COVID-19 severity. by Chrysovalantis Voutouri (612840)

“…<p><u>D</u>iagrams of peak viral load (A) and minimum oxygen saturation (SpO₂) (B) caused by viral infection as a function of viral immune evasion and relative decrease of virus replication rate, K_in, with antiviral drugs. ’Favorable’ outcomes for viral load correspond to low concentrations, while ’unfavorable’ outcomes relate to high concentrations. …”

Reduced thermal hypersensitivity in S1P₁^−/−mice. by Norbert Mair (113808)

Supporting information data. by Miriam Serrano Soliva (19485617)