Proton Transfer and Structure-Specific Fluorescence in Hydrogen Bond-Rich Protein Structures by Dorothea Pinotsi (1305144)

“…The importance of proton transfer on the intrinsic fluorescence observed in protein fibrils is signified by large reductions in the fluorescence intensity upon either fully protonating, or deprotonating, the fibrils at pH = 0 or 14, respectively. Thus, our results point to the existence of a structure-specific fluorophore that does not require the presence of aromatic residues or multiple bond conjugation that characterize conventional fluorescent systems. …”

Analysis of human gut microbiomes with BEEM-Static. by Chenhao Li (822769)

“…Each point represents one species in a sample. (C) Scatter plot showing the first two components from a principal component analysis of equilibrium abundances for samples (as predicted by BEEM-Static). …”

Proton Transfer and Structure-Specific Fluorescence in Hydrogen Bond-Rich Protein Structures by Dorothea Pinotsi (1305144)

“…The importance of proton transfer on the intrinsic fluorescence observed in protein fibrils is signified by large reductions in the fluorescence intensity upon either fully protonating, or deprotonating, the fibrils at pH = 0 or 14, respectively. Thus, our results point to the existence of a structure-specific fluorophore that does not require the presence of aromatic residues or multiple bond conjugation that characterize conventional fluorescent systems. …”

Stereoselective Alkali-Metal Catalysts for Highly Isotactic Poly(<i>rac</i>-lactide) Synthesis by Yangyang Sun (1446925)

“…The isoselective mechanism is chain-end control through the analysis of the stereoerrors in the microstructure of a final polymer; thus, isotactic multiblock structure polymers are obtained, and the highest melt point can reach 192.5 °C. …”

Manhattan plot of longitudinal brain volume change. by Rozanna Meijboom (7041257)

“…<p>Each point represents a tissue region within the given brain area category (x-axis). …”

Cross-sectional profile of the elevation of the ground surface and permafrost surface along two transects in the silty uplands under different disturbance regimes from 2009 to 2012 by Dana R Nossov (557153)

“…On average, fire caused a five-fold decrease in mean surface organic layer thickness, a doubling of water storage in the active layer, a doubling of thaw depth, an increase in soil temperature at the surface (−0.6 to +2.1 ° C) and at 1 m depth (−1.7 to +0.4 ° C), and a two-fold increase in net soil heat input. …”

<i>S</i>. <i>pneumoniae</i> RNA regulators are ligand responsive and most designed mutations function as anticipated. by Indu Warrier (581139)

“…<p><b>(A)</b> β-galactosidase activity of RNA reporter strains grown in the absence and presence of ligand or ligand precursor (0.3 μg/mL thiamine, 140 ng/mL riboflavin, 20 μg/mL uracil, 75 μg/mL glycine, 204 μg/mL tryptophan, 50 μg/mL guanine) demonstrates regulation of gene expression with a significant difference between expression in the two conditions. …”

Table_1_Methionine Antagonizes para-Aminosalicylic Acid Activity via Affecting Folate Precursor Biosynthesis in Mycobacterium tuberculosis.DOCX by Michael D. Howe (5952365)

“…Disruption of metM by transposon insertion resulted in a ≥30-fold decrease in uptake of methionine in M. bovis BCG, indicating that metM is the major facilitator of methionine transport. …”

Ongoing Phenotypic and Genomic Changes in Experimental Coevolution of RNA Bacteriophage Qβ and <em>Escherichia coli</em> by Akiko Kashiwagi (67598)

“…The phage counter-adapted by improving release efficiency with a change in host specificity and decrease in virulence. …”

Model-Driven Engineering of N‑Linked Glycosylation in Chinese Hamster Ovary Cells by Christopher S. Stach (7516934)

“…Through iterative engineering and model refinement, we rationally increase the fraction of bigalactosylated glycans five-fold from 11.9% to 61.9% and simultaneously decrease the glycan heterogeneity on the secreted IgG. …”

Induction of intracellular metabolic activators by sofosbuvir. by Yongyut Pewkliang (4799217)

“…The gene expression was shown as fold-changes over the corresponding untreated groups. imHC and Huh7 were infected with HCVcc (genotype 2a) at MOI 1 and subsequently exposed to various concentrations of sofosbuvir for 7 days. …”

Supplementary Figures from Impact of the 2015–2016 El Nino on the terrestrial carbon cycle constrained by bottom-up and top-down approaches by Ana Bastos (4808796)

“…Inversions and LSMs generally agree on the decrease and subsequent recovery of the land sink in response to the onset, peak and demise of El-Niño conditions and point to the decreased strength of the land carbon sink: by 0.4–0.7 PgC yr⁻¹ (inversions) and by 1.0 PgC yr⁻¹ (LSMs) during 2015/2016. …”

Supplementary Datasets from Impact of the 2015–2016 El Nino on the terrestrial carbon cycle constrained by bottom-up and top-down approaches by Ana Bastos (4808796)

“…Inversions and LSMs generally agree on the decrease and subsequent recovery of the land sink in response to the onset, peak and demise of El-Niño conditions and point to the decreased strength of the land carbon sink: by 0.4–0.7 PgC yr⁻¹ (inversions) and by 1.0 PgC yr⁻¹ (LSMs) during 2015/2016. …”

Examination of thioacetamide (TAA)-induced liver fibrosis in rats by gadoxetic acid-enhanced MRI. by Ya-Wen Chen (142312)

“…<p>(A) T1-weighted MRI images of Group 1 (TAA only, upper panel), 2 (TAA +0.25 g/kg SST) and 3 (TAA +1 g/kg SST) were shown at different time points (10, 20, 30, 40 50 and 60 min). …”

Intermittent fasting enhances long-term memory consolidation, adult hippocampal neurogenesis and expression of longevity gene Klotho (Microarray dataset) by Sandrine Thuret (10326662)

“…Relatively loose criteria were initially used to filter the data (to minimize analytical false negatives), but genes were required to pass these criteria for each of the four methods to be considered further (four out of four methods) to minimize analytical false positives. </p> <p>A fold change of 1.2 along with a t-test p-value of less than 0.05 was used in RMA and dChip, and a confidence of 50% or higher was used in the Drop Method. …”

Altered Transcript Levels for Genes in the Biosynthetic Pathway of Aliphatic Glucosinolates in the <i>35S:MYB</i> lines. by Ida Elken Sønderby (272735)

“…Dark color represents a change of 50 percent or more while the lighter color shows a change of less than 50 percent.…”

Depletion of TGF-β alters morbidity in HK/486-infected mice. by Christina M. Carlson (240307)

“…<p>Six hours before infection, BALB/c mice were treated with a TGF-β neutralizing antibody (1D11) or an isotype control antibody (IgG) at a dose of 0.5 mg/mouse and subsequently inoculated with PBS (control) or 10⁵ TCID₅₀ units of HK/486 virus (n = 15). …”

Effects of chlorpyrifos on the crustacean <i>Litopenaeus vannamei</i> by Edisson Duarte-Restrepo (8703723)

“…Catalase activity and LPO were elevated in the three tissues, whereas a decrease of AChE activities in the brain and an increase of GST activity in the hepatopancreas were observed.…”

Effect of CORT injections on depression-like behavior. by Suk-Yu Yau (205104)

“…<p>(<b>A</b> and <b>B</b>) Treatment with CORT increased immobility time in a dose-dependent manner while running decreased immobility time. * P<0.05; ** P<0.005 compared to control. …”

Evolutions of various contact fractions of the NCBD/ACTR complex at 475 K. by Weihong Zhang (188305)

“…The solid traces correspond to the best single exponential fits (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002353#pcbi-1002353-t001" target="_blank">Table 1</a> for the fitted kinetic constants). …”