Effect of deletion of the functional domains of INS-20 on <i>Cryptosporidium parvum</i>. by Yue Huang (285485)

“…Mice infected with the transgenic lines of INS-20ΔNter, INS-20ΔCter, and INS-20^HLLEQ/5A showed a 3-fold decrease in fecal luciferase activity compared to those infected with the IId-GFP line. …”

PPAR-α signaling, lipid metabolism-associated RNA changes and inferred signaling pathways. by Renée Deehan (326438)

“…See <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0035012#pone-0035012-g002" target="_blank"><i>Figure 2A</i></a> for treatment dosages. …”

Beta scores and variance in projection (VIP) values for the partial least squares analysis of samples sequenced in Oxford and Northumbria. by Helen R. Fryer (16828192)

“…*based upon a Ct value decrease of 3 being equivalent to a 10-fold increase in viral load [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1011461#ppat.1011461.ref034" target="_blank">34</a>].…”

Seasonal Variation in the Skin Transcriptome of Common Bottlenose Dolphins (<i>Tursiops truncatus</i>) from the Northern Gulf of Mexico by Frances M. Van Dolah (22016)

“…Persistent organic pollutants (POPs) in blubber changed concurrently, reaching >two-fold higher concentrations in summer compared to winter, due to a seasonal decrease in blubber thickness and loss of stored lipid. …”

Image 1_Zuoqing granules attenuate ulcerative colitis via macrophage polarization modulation: involvement of the PPAR-γ/NF-κB/STAT1 signaling axis.jpeg by Heng Deng (4402264)

“…</p>Results<p>ZQG treatment dose-dependently (1) ameliorated colonic mucosal damage, reducing histological scores by 52% compared to that in the model group, (2) modulated macrophage polarization by increasing the M2 phenotype (CD206⁺ cells, 3.25-fold increase) while decreasing M1 macrophages (CD86⁺ cells, 70% reduction), (3) upregulated PPAR-γ expression (2.0-fold increase) while suppressing NF-κB activation (43% decrease in p-NF-κB) and STAT1 signaling (48% and 40% reductions in protein and mRNA levels, respectively), and (4) rebalanced inflammatory cytokines, with 55%–62% reductions in TNF-α, IL-6, and IL-1β and 185%–210% increases in IL-10 and IL-4. …”

At clinically relevant concentrations the anaesthetic/amnesic thiopental but not the anticonvulsant phenobarbital interferes with hippocampal sharp wave-ripple complexes-2 by Costas Papatheodoropoulos (78587)

“…Note the great value dispersion of instant period during drug application at ≥50 μM. Data in "a" and "b" were obtained from two different slices. …”

Evidence of <em>Bacteroides fragilis</em> Protection from <em>Bartonella henselae</em>-Induced Damage by Linda Sommese (119244)

“…Moreover, immunohistochemistry analysis with anti-Bartonella showed that the number of positive cells per field decreased of at least 50% in the liver (20±4 <em>vs</em> 50±8), aorta (5±1 <em>vs</em> 10±2) and spleen (25±3 <em>vs</em> 40±6) sections of mice coinfected compared to mice infected only with <em>B. henselae</em>. …”

Simulations Demonstrating the Effects of Varying the Degree of Resistance on Treatment Success Rates by Marcel E Curlin (32388)

“…<p>As in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0030133#pcbi-0030133-g005" target="_blank">Figures 5</a> and <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0030133#pcbi-0030133-g006" target="_blank">6</a>, (A) and (C) demonstrate success rates as the duration of induction therapy is increased, and (B) and (D) demonstrate success rates over a range of induction therapy/therapy intensification start times. …”

Arachidonic Acid Randomizes Endothelial Cell Motion and Regulates Adhesion and Migration by Ninna Struck Rossen (204018)

Effect of Magnetic Baffles and Magnetic Nanofluid on Thermo-Hydraulic Characteristics of Dimple Mini Channel for Thermal Energy Applications by Souayeh, Basma

“…Hence, with the increase in the magnetic field, there is a decrease in pressure drop for both the cases and the pitches. …”
Get full text
Get full text
Get full text

Data_Sheet_1_Interaction of energy and sulfur microbial diet and smoking status with polygenic variants associated with lipoprotein metabolism.PDF by Haeng Jeon Hur (6808157)

“…The risk alleles of CETP_rs708272 and ALDH1A2_rs588136 were linked to increased expression in the heart and decreased in the brain, respectively. …”

Analysis of Transmission Electron Microscopy images of axons in zebrafish hindbrain and trunk regions (5 dpf). by Ping Song (169215)

“…Panels b, d, and f are amplifications of the boxed areas in panels a, c and e, respectively. The white rectangles in panels b, d, and f are amplifications of the areas marked with red 5-point stars. …”

The relationship between permafrost probability (PF) and organic layer thickness (OLT) by Kristofer D Johnson (557206)

“…Furthermore, when soil organic carbon was estimated using a relationship with thickness, the average increase in carbon in OLTd soils was almost four times greater compared to the average decrease in carbon in OLTs soils across all soil types. …”

Data_Sheet_2_Determination of factors associated with serum cholesterol response to dairy fat consumption in overweight adults: Secondary analysis from an RCT.docx by Aileen O'Connor (13191693)

“…A 6-week randomized parallel intervention trial was carried out in healthy volunteers (≥50 years, BMI ≥25 kg/m²). …”

Data_Sheet_1_Determination of factors associated with serum cholesterol response to dairy fat consumption in overweight adults: Secondary analysis from an RCT.docx by Aileen O'Connor (13191693)

“…A 6-week randomized parallel intervention trial was carried out in healthy volunteers (≥50 years, BMI ≥25 kg/m²). …”

Galectin-3 Up-Regulation in Hypoxic and Nutrient Deprived Microenvironments Promotes Cell Survival by Rafael Yamashita Ikemori (698128)

“…Inhibition of gal-3 expression using siRNA led to protein knockdown followed by a 1.7–2.2 fold increase in cell death. Similar results were also found in a human GBM cell line, T98G. …”

Identification of candidate genes associated with photosynthesis in eggplant under elevated CO₂ by Xiaoyong Xu (276757)

“…Net photosynthetic rate, light saturation point and intercellular CO₂ concentration of eggplant leaves increased by 86.11%, 49.94% and 102.06%, respectively, whereas light compensation point, dark breathing rate and stomatal conductance decreased by 35.90%, 27.30% and 26.03%, respectively. …”

The National One Week Prevalence Audit of Universal Meticillin-Resistant <i>Staphylococcus aureus</i> (MRSA) Admission Screening 2012 by Christopher Fuller (125431)

“…MRSA admission prevalence: 1% (median 0.9%) emergencies, 0.6% (median 0.4%) electives, 0.4% (median 0%) day-cases. Approximately 50% all MRSA identified was new. Inpatient MRSA point prevalence: 3.3% (median 2.9%). 104 (77%) trusts pre-emptively isolated patients with previous MRSA, 63 (35%) pre-emptively isolated admissions to “high-risk” specialties; 7 (5%) used PCR routinely. …”

Oxidative modification of Homer results in loss of solubility. by Igor Nepliouev (341769)

“…Cells were lysed in buffer containing 1% Triton, 8 M guanidine HCL, and 50 mM TCEP. Analysis of whole lysates showed a decrease in detectable Homer over time.…”

Resting energy expenditure adaptation after short-term caloric restriction in morbidly obese women by Andresa Toledo TRIFFONI-MELO (10470338)

“…Therefore, short-term caloric restriction in morbidly obese women led to a decrease in resting energy expenditure and fat-free mass, which suggests a rapid adaptation of energy expenditure.…”