Oct4 actively enhances the proliferation of ATSC cells along with the overexpression of pluripotency related genes and telomerase activation. by Jung Hwan Kim (259298)

DataSheet_1_An anti-sortilin affibody-peptide fusion inhibits sortilin-mediated progranulin degradation.docx by Moira Ek (19350559)

“…Treating PGRN-secreting and sortilin-expressing human glioblastoma U-251 cells with the fusion protein increased extracellular PGRN levels up to 2.5-fold, with an EC₅₀ value of 1.3 nM. Our results introduce A3-PGRN_C15* as a promising new agent with therapeutic potential for the treatment of frontotemporal dementia. …”

Synaptic remodeling and synaptic size distributions in long-term experiments. by Adiel Statman (638527)

“…Data is shown after smoothing with a 5 time point window to decrease the effects of measurement noise, and after normalizing the fluorescence values by the average over the entire experiment. …”

Caddisfly biodiversity in Pernambuco state, Brazil: overcoming the biodiversity knowledge shortfall and insights into the effects of climate change by Rafael Pereira (6635264)

“…Climate projections indicate a significant decrease in the temperature range, shifting from the current 13.2–33.6 °C to 17.9–33.6 °C, and precipitation range will decrease from 507 to 1948 mm³/year to 528–1428 mm³/year. …”

Neurons are uncorrelated during PABA and exhibit Poisson-like irregularity. by Nigel Stepp (683934)

“…Each data point represents the results of a parameter search at that network size, minimizing firing rate. …”

DataSheet1_Glycine Ameliorates Endoplasmic Reticulum Stress Induced by Thapsigargin in Porcine Oocytes.pdf by Sicong Yu (10732777)

Exploration of muscle loss and metabolic state during prolonged critical illness: Implications for intervention? by Liesl Wandrag (20467)

“…The data are consistent with a conclusion that a time based assumption of a tipping point does not exist.…”

Different types of history-dependent behavior one might observe. by Denise M. Wolf (272435)

“…Thus the trajectories appear to diverge from a common starting point and approach one of two asymptotic states. …”

Comparison of Genetic Structure of Epixylic Liverwort <i>Crossocalyx hellerianus</i> between Central European and Fennoscandian Populations by Eva Holá (771613)

“…Large populations possessed less SGS, with individuals showing a pronounced decrease in kinship over 50 cm of distance. …”

Pharmacological inhibition of cell death pathways protects neurons against glutamate-induced cell death. by Ujval Anilkumar (4598182)

“…Pre-treatment with Calpeptin, DPQ and SP 600125 significantly increased viability compared to no pre-treatment and this increased viability was primarily due to a decrease in apoptosis (*p = 0.0475 for all marked treatments compared to no pre-treatment).…”

Cohesin Is Limiting for the Suppression of DNA Damage–Induced Recombination between Homologous Chromosomes by Shay Covo (246428)

“…Unlike <em>RAD50</em> and <em>RAD51</em>, which play a direct role in HR, a 4-fold reduction in the number of essential <em>MCD1</em> sister chromatid cohesion subunit genes affected survival of gamma-irradiated G₂/M cells. …”

Dataset for: Dynamic classification using credible intervals in longitudinal discriminant analysis by David Michael Hughes (4110568)

“…Finally, we show that determining a stopping rule dynamically can be more accurate than specifying a set time point at which to decide on a patient's status. …”

Mathematical model for the interactions between the HPA axis and its inhibitory CNS regions. by Ben Ron Mizrachi (17593079)

“…CNS inhibits the hypothalamic input and thus leads to a decrease in <i>A</i>. <i>A</i> releases cortisol, which inhibits CNS through the glucocorticoid receptor GR. …”

Iron-based derepression mechanism of iron storage is not active at low external iron concentrations. by Oleg Agafonov (631744)

“…The FIT and IRT1-based high affinity uptake is able to keep the cytosolic iron at its set-point , while the S-based outflow controller (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0147120#pone.0147120.g006" target="_blank">Fig 6a</a>), responsible for iron storage, is inactive.…”

Yap knockdown in HUVECs results in G1 accumulation. by Zhewei Shen (688102)

“…HUVECs treated with siYAP exhibited a significant decrease in S-phase and increase in G1-phase at this time point. p-values were calculated by comparing each phase to the corresponding datasets from RISC-free control. *, p < 0.04; **, p < 0.007. …”

Single neuron preferences. by Simon Nougaret (17980269)

“…(C) Average response for each run of 3 subpopulations of neurons: all the neurons that respond to the appearance of the scene (left), and among these, neurons that prefer the first run with an increase in firing rate (center), and neurons that prefer the first run with a decrease in firing rate (right). Neural activity is aligned to the presentation of the scene (start of the Delay epoch), binned in a 200-ms window with a 25-ms step between each point, and normalized for each neuron by subtracting the mean activity and dividing by the standard deviation both calculated in a baseline period (−400 ms until the appearance of the scene). n = number of neurons. …”

Srp drives an overgrowth of the wing disc. by Kyra Campbell (582914)

“…Ratios show the reproducibility of the phenotype are shown. Scale bars A-C—100μm; J-L—50μm.</p>…”

Data Sheet 1_Thermophilic microbial agents promote the fermentation progression of spent mushroom compost and pig manure.docx by Hongbo Du (1270113)

“…<p>Livestock and poultry manure, as a significant organic resource, had an enormous annual production but a utilization rate of less than 50%. …”

Image_4_The COPII subunit MoSec24B is involved in development, pathogenicity and autophagy in the rice blast fungus.tif by Hui Qian (110856)

“…<p>The endoplasmic reticulum (ER) acts as the starting point of the secretory pathway, where approximately one-third of the proteins are correctly folded and modified, loaded into vesicles, and transported to the Golgi for further processing and modification. …”

Image_1_The COPII subunit MoSec24B is involved in development, pathogenicity and autophagy in the rice blast fungus.tif by Hui Qian (110856)

“…<p>The endoplasmic reticulum (ER) acts as the starting point of the secretory pathway, where approximately one-third of the proteins are correctly folded and modified, loaded into vesicles, and transported to the Golgi for further processing and modification. …”