Effects of the New Generation Synthetic Reconstituted Surfactant CHF5633 on Pro- and Anti-Inflammatory Cytokine Expression in Native and LPS-Stimulated Adult CD14⁺ Monoc... by Kirsten Glaser (846928)

“…In LPS-stimulated monocytes, exposure to CHF5633 led to a significant decrease in TNF-α mRNA (0.57 ± 0.23-fold, p = 0.043 at 4h; 0.56 ± 0.27-fold, p = 0.042 at 14h). …”

Temporal Trend in Young-Onset Type 2 Diabetes - the Macrovascular and Mortality Risk: Study of UK Primary Care Electronic Medical Records by Digsu N. Koye (8881108)

“…The incidence rates of ASCVD and ACM declined in people aged ≥50 years, but did not decrease in people <50 years. …”

Defective Resection at DNA Double-Strand Breaks Leads to <em>De Novo</em> Telomere Formation and Enhances Gene Targeting by Woo-Hyun Chung (248941)

“…In <em>sgs1</em>Δ <em>exo1</em>Δ mutants that form only very short ssDNA, allelic gene conversion decreases 5-fold and DSBs are repaired by BIR or <em>de novo</em> telomere formation resulting in loss of heterozygosity. …”

NF-κβ, COX, and ROS involvement in EP bridge formation. by Brett G. Zani (254541)

“…<b>C–D:</b> SC-514 or indomethacin (INDO, 50 µM), a COX pathway inhibitor, caused ∼2–3 fold increases in EP bridges, arrows denote EP bridges, for both EPs/ECs and EPs/FBs after 48 h, n = 6−8. …”

Data_Sheet_1_Hybrid Gibbsite Nanoplatelet/Cellulose Nanocrystal Multilayered Coatings for Oxygen Barrier Improvement.PDF by Maud Chemin (5931452)

“…The measurement of the oxygen transmission rate (OTR) at 23°C and 50% RH showed that the oxygen barrier properties of the bare substrates could be significantly improved (e.g., 75% decrease of the OTR) after the deposition of such thin (<100 nm) multilayered hybrid films. …”

Myotonia-causing mutations and the putative binding pocket of the 9-AC inhibitor. by Kaituo Wang (6193994)

“…Therefore, the phenotype may reflect a decreased chloride affinity of an extracellularly accessible site. …”

BTK Expression Levels Control DNA Binding Activity and Transcription Factor Function of Ikaros. by Hong Ma (48973)

“…Each siRNA was used at a 50 nM concentration. BTK siRNA (but not Ku80 siRNA) resulted in depletion of BTK protein without a decrease in the amount of IK protein. …”

Data_Sheet_1_Association between hemoglobin-to-red blood cell distribution width ratio and hospital mortality in patients with non-traumatic subarachnoid hemorrhage.PDF by Jiuling Liu (16327938)

“…The association between the HRR level and in-hospital mortality exhibited a non-linear relationship (p < 0.05). The threshold inflection point value of 9.50 was calculated using RCS analysis. …”

RAGE blocking and APP inhibition synergistically reduce oxidative stress, apoptosis and rescue sequential gliocentric cell fate change in DS HNPs. by Jie Lu (139953)

“…(B) Graphs show the S100B stimulation for 24 hours dose dependently increase H₂O₂ production and decrease mitochondrial membrane potential which can be blocked by RAGE antibody (1 µg/ml) or dalteparin sodium (1 IU/ml) (<b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0022126#pone.0022126.s005" target="_blank">Figure S5A</a></b>). …”

The airway intrinsic BX-C code determines the outcome of <i>hh</i> signaling. by Ryo Matsuda (685668)

“…Note that Salm expression in DT shows a posterior-to-anterior decrease. Upon overexpression of <i>Ubx</i> (G), <i>abdA</i> (H) or <i>AbdB</i> (I), DTa1 becomes negative for Kni and positive for Salm (asterisks). …”

Data_Sheet_1_Unequal Impact of COVID-19 on Private and Academic Neurosurgical Workforce: Results of an International Survey.PDF by Sami Ridwan (11510080)

“…</p><p>Conclusion: The lockdown imposed in many countries by the COVID-19 outbreak called for immediate modification of working routine and resulted in a dramatic decrease of elective surgical procedures. …”

Climatic factors driving vegetation declines in the 2005 and 2010 Amazon droughts by Wenqian Zhao (3937202)

“…The results showed that (i) in the Amazon vegetation greenness responded to precipitation, radiation and temperature, with apparent time lags for most averaging interval periods associated with vegetation index responses of 0–4, 0–9 and 0–6 months, respectively; (ii) on average, the three climatic factors without time lags explained 27.28±21.73% (mean±1 SD) of vegetation index variation in the Amazon basin, and this value increased by 12.22% and reached 39.50±27.85% when time lags were considered; (iii) vegetation greenness in this region in non-drought years was primarily affected by precipitation and shortwave radiation, and these two factors altogether accounted for 93.47% of the total explanation; and (iv) in the common epicenter of the two droughts, pixels with a significant variation in precipitation, radiation and temperature accounted for 36.68%, 40.07% and 10.40%, respectively, of all pixels showing a significant decrease in vegetation index in 2005, and 15.69%, 2.01% and 45.25% in 2010, respectively. …”

Table_1_In vitro investigation of the antiviral activity of propolis and chitosan nanoparticles against the genotype VII Newcastle disease virus.DOCX by Noura Alkhalefa (13387473)

“…The median tissue culture infectious dose (TCID50) assay demonstrated that the nanoparticles have antiviral effects after NDV exposure resulting in significant decrease in viral titer (TCID50) by 2, 2.66, and 2.5 log10 at 62 μg/ml of chitosan, 13 μg/ml of propolis, and 30 μg/ml of the propolis–chitosan mixture, respectively, compared with the control TCID50 value of 4 log10. …”

Table_1_In vitro investigation of the antiviral activity of propolis and chitosan nanoparticles against the genotype VII Newcastle disease virus.DOCX by Noura Alkhalefa (13387473)

“…The median tissue culture infectious dose (TCID50) assay demonstrated that the nanoparticles have antiviral effects after NDV exposure resulting in significant decrease in viral titer (TCID50) by 2, 2.66, and 2.5 log10 at 62 μg/ml of chitosan, 13 μg/ml of propolis, and 30 μg/ml of the propolis–chitosan mixture, respectively, compared with the control TCID50 value of 4 log10. …”

DNA replication in the micronuclei of CPA sired embryos. by Lisanne Grenier (339291)

“…(C) Comparison of the proportion of EdU positive MN in EdU positive cells in day 1 and day 3 embryos sired by CPA exposed males. A decrease in the proportion of functional MN incorporating EdU was observed in 8 cell embryos compared to 2 cell embryos. …”

Acute effects of different intensities and amounts of aerobic exercise on the concentrations of tryptophan and serotonin in physically active elderly women by Jônatas de França Barros (4657306)

“…<p></p><p>Aging causes a decrease in the concentration of serotonin, which in turn, can produce abnormalities of behavior as aggression, insomnia, suicidal or criminal behavior and loss of sexual desire. …”

Structure Based <i>In Silico</i> Analysis of Quinolone Resistance in Clinical Isolates of <i>Salmonella</i> Typhi from India by Manoj Kumar (205700)

“…The present study assists in understanding the underlying molecular and structural mechanism for decreased fluoroquinolone susceptibility in clinical isolates as a consequence of mutations in DNA Gyrase.…”

Enhancing <i>o</i>-cresol biodegradation in wastewater via <i>T. obliquus</i>/TiO₂ composite: construction and mechanistic insights by Daohong Zhang (1746094)

“…The results demonstrate a significant improvement, with the o-cresol degradation rate using the composite being 1.79 times higher than that of <i>T. obliquus</i> alone. …”

Few Single Nucleotide Variations in Exomes of Human Cord Blood Induced Pluripotent Stem Cells by Rui-Jun Su (396823)

“…These data demonstrate that point nucleotide mutations during cord blood reprogramming are negligible and that the inclusion of genome stabilizers like ZSCAN4 during reprogramming may further decrease reprogramming-associated mutations. …”

Effect of subthalamic nucleus lesion on the severity of L-DOPA-induced dyskinesia. by Asier Aristieta (312325)

“…Time course of axial, limb and orolingual AIMs scored in <i>(</i><b><i>C</i></b><i>)</i> STN-lesion and <i>(</i><b><i>D</i></b><i>)</i> STN-sham animal groups. The results show a significant decrease in AIMs scores after STN lesion. …”