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point decrease » point increase (Expand Search)
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29861
Synthesis and bioactivity of the γ-secretase modulator photo-probe AR243.
Published 2012“…AR243 caused a dose-dependent decrease in Aβ42 levels with a concomitant increase in Aβ38 levels, confirming its bioactivity as a potent GSM with an IC<sub>50</sub> for Aβ42 reduction of 290 nM.…”
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29862
Reduction of CSF leucocyte count and induction of apoptosis by roscovitine <i>in vivo.</i>
Published 2009“…<p>Wild type mice were subjected to pneumococcal meningitis by bacterial injection into the cisterna magna and treated either with a combination of ceftriaxone (100 mg/kg, intraperitoneally) and roscovitine (50 mg/kg intraperitoneally) or ceftriaxone and the vehicle of roscovitine (PBS+20% DMSO). …”
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29863
Population statistics of latency tuning.
Published 2012“…(C) A scatter plot of <i>A</i> vs. <i>B</i> for first spike latency (each point represents one unit; correlation coefficient 0.85). …”
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29864
Rheological behavior of concentrated tucupi
Published 2018“…Rheology at 25 °C indicated that the partial gelification of starch during concentration causes a decrease in the product’s viscosity and, if the concentration is carried out at a temperature that favors total starch gelification, the product’s viscosity increases. …”
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29865
Rheological behavior of concentrated tucupi
Published 2019“…Rheology at 25 °C indicated that the partial gelification of starch during concentration causes a decrease in the product’s viscosity and, if the concentration is carried out at a temperature that favors total starch gelification, the product’s viscosity increases. …”
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29866
Enhanced electropermeabilization of peroxidized cells with both ultra-short and conventional electric pulse treatments.
Published 2013“…Peroxidized cells treated with a single 100 µs, 50 kV/m pulse show a similar increased susceptibility to electropermeabilization. …”
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29867
Molecular and Structural Changes in Induced-Brain Stroke Tissue Using FTIR Imaging Spectroscopy, Scanning Electron and Atomic Force Microscopy
Published 2016“…The infrared spectrum images showed a decrease in the lipid content of the white matter associated with the induced stroke brain sections. …”
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29868
Simulated temporal dynamics in E2F activation using the stochastic Rb-E2F model.
Published 2010“…<p>(A) Stochastic simulations (25 events) exhibit variable time delays in E2F activation, as shown in gray lines. …”
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29869
DataSheet1_Non-target screening to track contaminant removal and release during nature-based water treatment.docx
Published 2024“…Natural products predominantly increased after RB contact, while compounds exhibited a significant 75% decrease in peak area are mainly pharmaceuticals. …”
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29870
Table7_Non-target screening to track contaminant removal and release during nature-based water treatment.xlsx
Published 2024“…Natural products predominantly increased after RB contact, while compounds exhibited a significant 75% decrease in peak area are mainly pharmaceuticals. …”
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29871
Table6_Non-target screening to track contaminant removal and release during nature-based water treatment.xlsx
Published 2024“…Natural products predominantly increased after RB contact, while compounds exhibited a significant 75% decrease in peak area are mainly pharmaceuticals. …”
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29872
Improving the measurement of TMS-assessed voluntary activation in the knee extensors
Published 2019“…In a fresh state, potentiated twitch force was unchanged following 1x5C but decreased following 2x5C (<i>P</i><0.05). …”
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29873
Transfection of catalytically active BPLF1 inhibits activation of the DDR and DNA repair in etoposide treated HeLa cells.
Published 2021“…Mean ± SE of two or three independent experiments where a minimum of 50 BPLF1 positive and 50 BPLF1 negative cells was scored in each condition.…”
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29874
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29875
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29876
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29877
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29878
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29879
Selective VCP inhibition induces significant cell cycle arrest in G2/M phase.
Published 2016“…<p>(A) Following a 24-hour treatment period with control-PBS, NMS-873/DBeQ (50μM, positive-control), dendrimer (DDN) or dendrimer-encapsulated DBeQ (DDN<sup>DBeQ</sup>, 50 μM), cells were fixed with ice-cold 70%-ethanol followed by staining with propidium iodide (10μg/mL) for 1 hour. …”
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29880