Showing 301 - 320 results of 49,013 for search '(( 50 ((a decrease) OR (nn decrease)) ) OR ( a ((fold decrease) OR (point decrease)) ))', query time: 0.94s Refine Results
  1. 301

    PIN1 silencing leads to decreases in the protein levels of HIF-1α. by Hyeong-jun Han (846566)

    Published 2016
    “…<p>A) Silencing of PIN1 expression via RNAi reduces the protein levels of HIF-1α in HCT116 cells. …”
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    Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

    Published 2022
    “…Compound <b>4f</b> exhibited potent EGFR inhibitory activity with an IC<sub>50</sub> value of 61 nM compared to that of Tamoxifen (IC<sub>50</sub> value of 69 nM), with EGFR inhibition of 83 and 84%, respectively, at a concentration of 10 μM. …”
  5. 305

    Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

    Published 2022
    “…Compound <b>4f</b> exhibited potent EGFR inhibitory activity with an IC<sub>50</sub> value of 61 nM compared to that of Tamoxifen (IC<sub>50</sub> value of 69 nM), with EGFR inhibition of 83 and 84%, respectively, at a concentration of 10 μM. …”
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    Drugs susceptibility profile (EC<sub>50</sub> values and Fold-change) to the antileishmanials in all polyene resistant lines of <i>Leishmania</i> spp. by Edubiel A. Alpizar-Sosa (13848145)

    Published 2022
    “…Values higher and lower than 1, indicate a decrease and increase in susceptibility, respectively.…”
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    GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) by F. Anthony Romero (2452198)

    Published 2017
    “…Constraining the aniline of <b>1</b> into a tetrahydroquinoline motif maintained potency and increased selectivity 2-fold. …”
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