Showing 40,481 - 40,500 results of 49,525 for search '(( 50 ((a decrease) OR (nn decrease)) ) OR ( a ((fold decrease) OR (point decrease)) ))', query time: 1.23s Refine Results
  1. 40481

    Table_1_Seasonal Hypometabolism in Female Moose.DOCX by Anne Randi Græsli (8800793)

    Published 2020
    “…Based on previous calibration studies, MR decreased by 60% from the highest to the lowest point. …”
  2. 40482

    Image_7_Spectrum Degradation of Hippocampal LFP During Euthanasia.JPEG by Yuchen Zhou (1601536)

    Published 2021
    “…The larger loops, comprising a larger population, are fault-tolerant to a point capable of maintaining their activity before a final collapse.…”
  3. 40483

    Quantification of temperature course data. by Kristen J. Holmes (502552)

    Published 2013
    “…<p>(A) Double-blinded quantification of data from experiments presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0084060#pone-0084060-g003" target="_blank">Figure 3</a>. …”
  4. 40484

    <i>In silico</i> inflammation profiles of aging in human tissues: Sex-specific lymphocyte signatures in skin. by William R. Swindell (175427)

    Published 2012
    “…Dark red colors indicate cases in which signature transcripts for a given cell population increase with age (i.e., the ratio of age-increased to age-decreased signature transcripts is greater than one). …”
  5. 40485

    Meta-analysis of 3 manipulations of the insulin/Tor signaling identifies rover-biased genes. by Clement F. Kent (260706)

    Published 2009
    “…<p>Three published studies decreased insulin/Tor effects via (A) ablation of <i>dilp3</i> expressing cells <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000609#pgen.1000609-Buch1" target="_blank">[28]</a>, (B) overexpression of constitutively active <i>foxo </i><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000609#pgen.1000609-Gershman1" target="_blank">[29]</a>, or (C) rapamycin <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000609#pgen.1000609-Guertin1" target="_blank">[30]</a>. …”
  6. 40486

    The expression profiles of the selected IFNα-stimulated genes are negatively influenced by the intracellular factor IRF2. by Katharina Robichon (8445099)

    Published 2020
    “…(<b>D</b>) Upregulation of gene expression by decreased <i>IRF2</i> expression. Huh7.5 cells were incubated with 50 nM siRNA directed against <i>IRF2</i> (orange) or non-targeting control (blue) for 24 hours, and then treated with 500 U/ml IFNα. …”
  7. 40487

    Prevalence of malnutrition may impact global viral evolutionary patterns. by Rebekah Honce (9238696)

    Published 2020
    “…<p>Worldwide rates of obesity are projected to reach over 50% by 2050. Additionally, undernutrition of both children and adults continues to be a global health crisis. …”
  8. 40488

    Effect of on Bepridil on APP processing. by Kamran Honarnejad (485648)

    Published 2013
    “…Sulindac sulfide (50 µM) was used as a γ-secretase modulator control. …”
  9. 40489

    Human heart mtDNA topology changes in early childhood and in mitochondrial disorders involving mutations in Twinkle and PolG. by Jaakko L. O. Pohjoismäki (249430)

    Published 2010
    “…<p>The basis of the assignment of the different molecular forms is presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0010426#pone.0010426-Pohjoismki1" target="_blank">[5]</a>. …”
  10. 40490

    Table_2_Antimony resistance mechanism in genetically different clinical isolates of Indian Kala-azar patients.docx by Supriya Khanra (5245634)

    Published 2022
    “…<p>The central theme of this enterprise is to find common features, if any, displayed by genetically different antimony (Sb)-resistant viscerotropic Leishmania parasites to impart Sb resistance. In a limited number of clinical isolates (n = 3), we studied the breadth of variation in the following dimensions: (a) intracellular thiol content, (b) cell surface expression of glycan having N-acetyl-D-galactosaminyl residue as the terminal sugar, and (c) gene expression of thiol-synthesizing enzymes (CBS, MST, gamma-GCS, ODC, and TR), antimony-reducing enzymes (TDR and ACR2), and antimonial transporter genes (AQP1, MRPA, and PRP1). …”
  11. 40491

    Identification of Glycoprotein Markers for Pancreatic Cancer CD24<sup>+</sup>CD44<sup>+</sup> Stem-like Cells Using Nano-LC–MS/MS and Tissue Microarray by Jianhui Zhu (678784)

    Published 2012
    “…Herein, the malignant phenotype of pancreatic cancer stem-like CD24<sup>+</sup>CD44<sup>+</sup> cells was isolated from a human pancreatic carcinoma cell line (PANC-1) and demonstrated 4-fold increased invasion ability compared to CD24<sup>–</sup>CD44<sup>+</sup> cells. …”
  12. 40492

    Table_1_Antimony resistance mechanism in genetically different clinical isolates of Indian Kala-azar patients.xlsx by Supriya Khanra (5245634)

    Published 2022
    “…<p>The central theme of this enterprise is to find common features, if any, displayed by genetically different antimony (Sb)-resistant viscerotropic Leishmania parasites to impart Sb resistance. In a limited number of clinical isolates (n = 3), we studied the breadth of variation in the following dimensions: (a) intracellular thiol content, (b) cell surface expression of glycan having N-acetyl-D-galactosaminyl residue as the terminal sugar, and (c) gene expression of thiol-synthesizing enzymes (CBS, MST, gamma-GCS, ODC, and TR), antimony-reducing enzymes (TDR and ACR2), and antimonial transporter genes (AQP1, MRPA, and PRP1). …”
  13. 40493

    Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors by Mirko Scortichini (4007366)

    Published 2022
    “…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i><sub>i</sub> = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i><sub>i</sub> = 0.436 nM) substitution of the <i>N</i><sup>4</sup>-benzyloxy group decreased <i>K</i><sub>i</sub> by ∼20-fold. Primary alkylamine derivatives coupled through a <i>p</i>-amido group with a varying methylene chain length (<b>24</b> and <b>25</b>) were functionalized congeners, for subsequent conjugation to carrier or reporter moieties. …”
  14. 40494

    Identification of Glycoprotein Markers for Pancreatic Cancer CD24<sup>+</sup>CD44<sup>+</sup> Stem-like Cells Using Nano-LC–MS/MS and Tissue Microarray by Jianhui Zhu (678784)

    Published 2012
    “…Herein, the malignant phenotype of pancreatic cancer stem-like CD24<sup>+</sup>CD44<sup>+</sup> cells was isolated from a human pancreatic carcinoma cell line (PANC-1) and demonstrated 4-fold increased invasion ability compared to CD24<sup>–</sup>CD44<sup>+</sup> cells. …”
  15. 40495

    Presentation_2_Antimony resistance mechanism in genetically different clinical isolates of Indian Kala-azar patients.pptx by Supriya Khanra (5245634)

    Published 2022
    “…<p>The central theme of this enterprise is to find common features, if any, displayed by genetically different antimony (Sb)-resistant viscerotropic Leishmania parasites to impart Sb resistance. In a limited number of clinical isolates (n = 3), we studied the breadth of variation in the following dimensions: (a) intracellular thiol content, (b) cell surface expression of glycan having N-acetyl-D-galactosaminyl residue as the terminal sugar, and (c) gene expression of thiol-synthesizing enzymes (CBS, MST, gamma-GCS, ODC, and TR), antimony-reducing enzymes (TDR and ACR2), and antimonial transporter genes (AQP1, MRPA, and PRP1). …”
  16. 40496

    GD3 Synthase Overexpression Sensitizes Hepatocarcinoma Cells to Hypoxia and Reduces Tumor Growth by Suppressing the cSrc/NF-κB Survival Pathway by Josep M. Lluis (256726)

    Published 2009
    “…<div><h3>Background</h3><p>Hypoxia-mediated HIF-1α stabilization and NF-κB activation play a key role in carcinogenesis by fostering cancer cell survival, angiogenesis and tumor invasion. …”
  17. 40497

    Presentation_3_Antimony resistance mechanism in genetically different clinical isolates of Indian Kala-azar patients.pptx by Supriya Khanra (5245634)

    Published 2022
    “…<p>The central theme of this enterprise is to find common features, if any, displayed by genetically different antimony (Sb)-resistant viscerotropic Leishmania parasites to impart Sb resistance. In a limited number of clinical isolates (n = 3), we studied the breadth of variation in the following dimensions: (a) intracellular thiol content, (b) cell surface expression of glycan having N-acetyl-D-galactosaminyl residue as the terminal sugar, and (c) gene expression of thiol-synthesizing enzymes (CBS, MST, gamma-GCS, ODC, and TR), antimony-reducing enzymes (TDR and ACR2), and antimonial transporter genes (AQP1, MRPA, and PRP1). …”
  18. 40498

    Presentation_1_Antimony resistance mechanism in genetically different clinical isolates of Indian Kala-azar patients.pptx by Supriya Khanra (5245634)

    Published 2022
    “…<p>The central theme of this enterprise is to find common features, if any, displayed by genetically different antimony (Sb)-resistant viscerotropic Leishmania parasites to impart Sb resistance. In a limited number of clinical isolates (n = 3), we studied the breadth of variation in the following dimensions: (a) intracellular thiol content, (b) cell surface expression of glycan having N-acetyl-D-galactosaminyl residue as the terminal sugar, and (c) gene expression of thiol-synthesizing enzymes (CBS, MST, gamma-GCS, ODC, and TR), antimony-reducing enzymes (TDR and ACR2), and antimonial transporter genes (AQP1, MRPA, and PRP1). …”
  19. 40499

    Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors by Mirko Scortichini (4007366)

    Published 2022
    “…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i><sub>i</sub> = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i><sub>i</sub> = 0.436 nM) substitution of the <i>N</i><sup>4</sup>-benzyloxy group decreased <i>K</i><sub>i</sub> by ∼20-fold. Primary alkylamine derivatives coupled through a <i>p</i>-amido group with a varying methylene chain length (<b>24</b> and <b>25</b>) were functionalized congeners, for subsequent conjugation to carrier or reporter moieties. …”
  20. 40500

    Competitive bio-panning assay shows specific binding of T7-ATERF-1 clone to the three strains of <i>Pseudomonas</i>. by Cristina Rioja (277145)

    Published 2013
    “…<p>(<b>A</b>) Competition between T7-ATERF-1 phage (which expresses ATERF-1 polypeptide) and T7-C1 (competing phage randomly selected). …”