qRT-PCR analysis of RPE and retinal- specific genes in homozygous <i>Mfrp^rd6</i>, <i>Tulp1^tvrm124 and Rpe65^tvrm148</i> mutants. by Ramani Soundararajan (651915)

“…<p>(A) In homozygous <i>Mfrp^rd6</i> mutant mice, the transcripts in the visual cycle (<i>Rpe65, Lrat</i> and <i>Rgr</i>), phototransduction pathway (<i>Rgs9</i>, <i>GuCa1b</i>, <i>Pde6a</i>) and structural components of rods and cones (<i>Fscn2</i> and <i>RpGrip1</i>) were significantly decreased relative to the wild-type control (B6/J), validating the microarray results. …”

Partial Agonist, Telmisartan, Maintains PPARγ Serine 112 Phosphorylation, and Does Not Affect Osteoblast Differentiation and Bone Mass by Vipula Kolli (561234)

“…TEL decreased ^S273pPPARγ and did not affect ^S112pPPARγ levels in a model of marrow MSC differentiation, U-33/γ2 cells. …”

Evolution in the total number of confirmed infections across multiple countries and simulated settings. by Vincenzo G. Fiore (10510274)

Temporal Gene Expression Profiling during Rat Femoral Marrow Ablation-Induced Intramembranous Bone Regeneration by Joel K. Wise (240576)

“…Adipogenic marker genes were found within variable/decreased expression groups, emphasizing that adipogenesis was inhibited during osteogenesis. …”

Effect of miR-7974 mimic transfection on proliferation of MDA-MB-453 cells together with changes in protein and gene expression levels of LC3B. by Stralina Eneh (21213312)

“…Representative western blots were cropped from respective western blot images for the protein of interest and grouped together. GAPDH was used as a reference protein. <b>(B)</b> The fold change of total protein levels of LC3B between negative control/cells only samples and miR-7974-treated samples were statistically significant. …”

Correlated Ligand Dynamics in Oxyiron Picket Fence Porphyrins: Structural and Mössbauer Investigations by Jianfeng Li (386792)

“…All dioxygen complexes have a crystallographically required 2-fold axis of symmetry that limits the accuracy of the determined Fe–O₂ geometry. …”

Correlated Ligand Dynamics in Oxyiron Picket Fence Porphyrins: Structural and Mössbauer Investigations by Jianfeng Li (386792)

“…All dioxygen complexes have a crystallographically required 2-fold axis of symmetry that limits the accuracy of the determined Fe–O₂ geometry. …”

Defining the threshold of error-induced extinction. by Alan J. Herr (202094)

“…<p>A) Plasmid shuffling experiments to reveal synthetic interactions between <i>pol3-01,eex</i> alleles and MMR mutations. …”

Sensory axons, but not soma, from Type III Nrg1^+/− mice show reduced capsaicin responsiveness compared to axons from WT mice. by Sarah E. Canetta (46254)

“…Averages of 5 animals per genotype were compared using a Student's t-test. Type III Nrg1^+/− axons showed a significantly decreased response to capsaicin (p<0.05), but not to KCl, relative to WTs. …”

Correlated Ligand Dynamics in Oxyiron Picket Fence Porphyrins: Structural and Mössbauer Investigations by Jianfeng Li (386792)

“…All dioxygen complexes have a crystallographically required 2-fold axis of symmetry that limits the accuracy of the determined Fe–O₂ geometry. …”

Tracking RC migration into the lipid matrix reveals the existence of concentration gradients. by Ellen Wallace (207446)

“…D: Quantitation of RC concentration using color saturation values of images, like those in A and B. Here, it is most evident that the concentration of RC in region 1 rapidly decreases and stabilizes at a minimum after ∼1 hour. …”

Suppression of uPA and uPAR Attenuates Angiogenin Mediated Angiogenesis in Endothelial and Glioblastoma Cell Lines by Hari Raghu (242948)

“…</p><h3>Methodology/Principal Findings</h3><p>In the present study, we have attempted to investigate the mechanism by which uPA/uPAR downregulation by shRNA inhibits angiogenesis in endothelial and glioblastoma cell lines. uPA/uPAR downregulation by shRNA in U87 MG and U87 SPARC co-cultures with endothelial cells inhibited angiogenesis as assessed by <em>in vitro</em> angiogenesis assay and <em>in vivo</em> dorsal skin-fold chamber model in nude mice. Protein antibody array analysis of co-cultures of U87 and U87 SPARC cells with endothelial cells treated with pU2 (shRNA against uPA and uPAR) showed decreased angiogenin secretion and angiopoietin-1 as well as several other pro-angiogenic molecules. …”

DataSheet_2_Cultivar-dependent differences in tuber growth cause increased soil resistance in potato fields.xlsx by Patrick Skilleter (16023374)

“…In a controlled environment trial with young (before tuber initiation) plants, roots of cv. …”

DataSheet_3_Cultivar-dependent differences in tuber growth cause increased soil resistance in potato fields.docx by Patrick Skilleter (16023374)

“…In a controlled environment trial with young (before tuber initiation) plants, roots of cv. …”

Table_2_Exploring the Role of Chemokine Receptor 6 (Ccr6) in the BXD Mouse Model of Gulf War Illness.XLS by Jun Gao (203098)

“…Its mean transcript abundance in PFC of BXD mice decreased 1.6-fold (p < 0.0001) in the CORT+DFP group. …”

Table_3_Exploring the Role of Chemokine Receptor 6 (Ccr6) in the BXD Mouse Model of Gulf War Illness.XLS by Jun Gao (203098)

“…Its mean transcript abundance in PFC of BXD mice decreased 1.6-fold (p < 0.0001) in the CORT+DFP group. …”

Neuronal loss of AMPK activity causes progressive sleep fragmentation. by Stanislav Nagy (570925)

“…<p>(A-B) Quantification of average bout durations (A) and average bout numbers (B) during day and night for <i>elav>Dcr-2/+</i> (n = 32), <i>UAS-alc-RNAi(KK)/+</i> (n = 32), <i>elav>Dcr-2</i>, <i>alc-RNAi(KK)</i> (n = 31), <i>UAS-alc-RNAi(8057-R2)/+</i> (n = 32), <i>elav>Dcr-2</i>, <i>alc-RNAi(8057-R2)</i> (n = 32), <i>UAS-AMPKα-DN/+</i> (n = 32), <i>elav>Dcr-2</i>, <i>AMPKα-DN</i> (n = 31). …”

FMNL3 mediates invasion of gonococcal colonies in macrophages. by Stanimir S. Ivanov (3394922)

“…<p><b>(A-B)</b> qPCR mRNA expression analyses for the members of the formin family in U937 MFs are shown. mRNA abundance relative to <i>gapdh</i> mRNA is shown in <b>(A)</b>. …”

Inhibiting NO signaling in nitrite-exposed embryos partially rescued defective development of cardiac valve in zebrafish embryos. by Junbo Li (337487)

“…<p>(A) The cGMP level was dramatically increased in the nitrite-exposed embryos at 24, 36, 48 and 76 hpf, respectively. **: P<0.01. …”

CFTR Delivery to 25% of Surface Epithelial Cells Restores Normal Rates of Mucus Transport to Human Cystic Fibrosis Airway Epithelium by Liqun Zhang (115900)

“…<div><p>Dysfunction of CFTR in cystic fibrosis (CF) airway epithelium perturbs the normal regulation of ion transport, leading to a reduced volume of airway surface liquid (ASL), mucus dehydration, decreased mucus transport, and mucus plugging of the airways. …”