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41661
Constitutively active ROS detoxifying responses reduce MBR.
Published 2017“…<p>(<b>A</b>) Indels (point mutations) (SNAs) and amplification (GCR), depicted here normalized to the wild-type, are reduced proportionately by <i>soxR104</i> and <i>oxyR2</i> alleles, which constitutively activate the SoxR and OxyR responses respectively. …”
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41662
Image_2_Hypermethylation of the Promoter of miR-338-5p Mediates Aberrant Expression of ETS-1 and Is Correlated With Disease Severity Of Astrocytoma Patients.jpg
Published 2021“…<p>The pro-oncogene ETS-1 (E26 transformation-specific sequence 1) is a key regulator of the proliferation and invasion of cancer cells. …”
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41663
Image_4_Mutation of the Polyproline Sequence in CD3ε Evidences TCR Signaling Requirements for Differentiation and Function of Pro-Inflammatory Tγδ17 Cells.tif
Published 2022“…<p>Tγδ17 cells have emerged as a key population in the development of inflammatory and autoimmune conditions such as psoriasis. …”
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41664
Systemic Delivery of Anti-amyloid-β antibody, 6E10, binds differently in brain tissue of amyloid-β expressing TgCRND8 mice vs. that of native wild type mice.
Published 2012“…<p>(A) Percentage injected dose per gram of tissue, as quantified by PET, differentiates between TgCRND8 (unfilled shapes) and wild type mice (filled shapes) at 4 h (p = 0.041) using 6E10-<sup>64</sup>Cu(diamonds). …”
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41665
Table_1_Long-Term Retinal Neurovascular and Choroidal Changes After Panretinal Photocoagulation in Diabetic Retinopathy.DOCX
Published 2021“…Global loss volume and focal loss volume significantly decreased at the same time point (p < 0.05).</p><p>Conclusion: The unchanged BCVA, VD, the thickness of RNFL and GCC, and SFCT during the 12-month follow-up period suggest that PRP may prevent the retinal neurovascular and choroidal damage.…”
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41666
Splenic DCs remain quiescent following interaction with donor apoptotic cells in vivo.
Published 2013“…<p>A) B6 mice were left untreated or injected i.v. with PKH67-labeled BALB/c apoptotic splenocytes. …”
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41667
Image_2_Mutation of the Polyproline Sequence in CD3ε Evidences TCR Signaling Requirements for Differentiation and Function of Pro-Inflammatory Tγδ17 Cells.tif
Published 2022“…<p>Tγδ17 cells have emerged as a key population in the development of inflammatory and autoimmune conditions such as psoriasis. …”
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41668
Image_3_Mutation of the Polyproline Sequence in CD3ε Evidences TCR Signaling Requirements for Differentiation and Function of Pro-Inflammatory Tγδ17 Cells.tif
Published 2022“…<p>Tγδ17 cells have emerged as a key population in the development of inflammatory and autoimmune conditions such as psoriasis. …”
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41669
Table_2_Heterozygous p53-R280T Mutation Enhances the Oncogenicity of NPC Cells Through Activating PI3K-Akt Signaling Pathway.XLS
Published 2020“…<p>A heterozygous point mutation of p53 gene at codon 280 from AGA to ACA (R280T) frequently occurs in nasopharyngeal carcinoma (NPC) cell lines, and about 10% NPC tissues. …”
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41670
Directional Droplet Transport Mediated by Circular Groove Arrays. Part I: Experimental Findings
Published 2020“…The rebouncing height was slightly dependent on the initial polar coordinate of the impact point for a fixed <i>We</i>, whereas it grew for <i>We</i> > 20. …”
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41671
Relevance of BMP4 signaling in proliferation and viability in ALL-MSCs.
Published 2014“…<p>(A) Effects of different doses of dorsomorphin, an inhibitor of the canonical BMP signaling pathway, on the viability and proliferation of Healthy-MSCs and ALL- MSCs. …”
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41672
Data_Sheet_1_Nε-Lysine Acetylation of the Histone-Like Protein HBsu Regulates the Process of Sporulation and Affects the Resistance Properties of Bacillus subtilis Spores.PDF
Published 2022“…Using our collection of point mutations that mimic the acetylated and unacetylated forms of HBsu, we first determined if acetylation affects the process of sporulation, by determining the overall sporulation frequencies. …”
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41673
Table_5_Heterozygous p53-R280T Mutation Enhances the Oncogenicity of NPC Cells Through Activating PI3K-Akt Signaling Pathway.XLS
Published 2020“…<p>A heterozygous point mutation of p53 gene at codon 280 from AGA to ACA (R280T) frequently occurs in nasopharyngeal carcinoma (NPC) cell lines, and about 10% NPC tissues. …”
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41674
Table_4_Heterozygous p53-R280T Mutation Enhances the Oncogenicity of NPC Cells Through Activating PI3K-Akt Signaling Pathway.XLS
Published 2020“…<p>A heterozygous point mutation of p53 gene at codon 280 from AGA to ACA (R280T) frequently occurs in nasopharyngeal carcinoma (NPC) cell lines, and about 10% NPC tissues. …”
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41675
Illustration of the method used to identify the optimal tolerance <i>τ</i><sub><i>b</i></sub>.
Published 2018“…The point <i>τ</i><sub><i>b</i></sub> is taken to be the threshold that minimises the mean error between <i>χ</i> and the piecewise linear interpolant.…”
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41676
Proteomic analysis for busulfan-induced spermatogenesis disorder
Published 2024“…The busulfan-treated mouse testes were subjected to label-free quantification proteomics, which revealed 190 significantly downregulated proteins including lactate dehydrogenase A like 6B (LDHAL6B) and ubiquitin-specific protease 7 (USP7). …”
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41677
Table_1_Heterozygous p53-R280T Mutation Enhances the Oncogenicity of NPC Cells Through Activating PI3K-Akt Signaling Pathway.DOC
Published 2020“…<p>A heterozygous point mutation of p53 gene at codon 280 from AGA to ACA (R280T) frequently occurs in nasopharyngeal carcinoma (NPC) cell lines, and about 10% NPC tissues. …”
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41678
Table_6_Heterozygous p53-R280T Mutation Enhances the Oncogenicity of NPC Cells Through Activating PI3K-Akt Signaling Pathway.XLS
Published 2020“…<p>A heterozygous point mutation of p53 gene at codon 280 from AGA to ACA (R280T) frequently occurs in nasopharyngeal carcinoma (NPC) cell lines, and about 10% NPC tissues. …”
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41679
Table_1_Evaluation of the Direct Effect of Bilateral Deep Brain Stimulation of the Subthalamic Nucleus on Levodopa-Induced On-Dyskinesia in Parkinson's Disease.docx
Published 2021“…The active contacts which correspond to good effect for dyskinesia were located above the STN, and the mean coordinate was 13.05 ± 1.24 mm lateral, −0.13 ± 1.16 mm posterior, and 0.72 ± 0.78 mm superior to the midcommissural point.</p><p>Conclusions: High-frequency electrical stimulation of the area above the STN can directly suppress levodopa-induced on-dyskinesia.…”
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41680
Data_Sheet_1_Resting-State Brain Variability in Youth With Attention-Deficit/Hyperactivity Disorder.docx
Published 2022“…The imaging data were cross-sectionally collected for each participant at one time point. We observed a greater number of significant BOLD signal changes and higher-order polynomial significant associations in youth with ADHD. …”