Table_2_Network Biology Identifies Novel Regulators of CFTR Trafficking and Membrane Stability.xlsx by Cláudia Almeida Loureiro (6796022)

“…Although small-molecule compounds have been identified and commercialized that can correct its folding or gating, an efficient retention of F508del CFTR at the PM has not yet been explored pharmacologically despite being recognized as a crucial factor for improving functional rescue of chloride transport. …”

Table_1_Network Biology Identifies Novel Regulators of CFTR Trafficking and Membrane Stability.xlsx by Cláudia Almeida Loureiro (6796022)

“…Although small-molecule compounds have been identified and commercialized that can correct its folding or gating, an efficient retention of F508del CFTR at the PM has not yet been explored pharmacologically despite being recognized as a crucial factor for improving functional rescue of chloride transport. …”

Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis by Lorena Fernandez-Mosquera (5077820)

“…MCOLN1 is regulated by phosphoinositide kinase PIKFYVE and its product PtdIns(3,5)P₂, which is also decreased in RC-deficiency. Notably, reactivation of AMPK, in a PIKFYVE-dependent manner, or of MCOLN1 in RC-deficient cells, restores lysosomal hydrolytic capacity. …”

Data_Sheet_1_Cognitive trajectories: exploring the predictive role of subjective cognitive decline and awareness of age-related changes for cognitive functioning.PDF by Serena Sabatini (10681579)

“…In Class 1 (N = 182) mean WM at baseline was 31.20; this decreased by 2.48 points each year. In Class 2 (N = 119) mean WM at baseline was 23.12; this increased by 3.28 points each year. …”

Data Sheet 1_Pediatric bacterial meningitis in southern China: analysis of 838 cases.docx by Lianfeng Chen (11537137)

“…Moreover, 92.0% of the patients were graded five Glasgow outcome scale (GOS) points at discharge. Differences in symptoms, pathogens, CSF results, brain MRI, and GOS points were observed across age groups (neonate [29 days, 12 months) and aged ≥12 months). …”

Lung bacterial burden as measured by colony forming units (CFU) over time. by S. Anisah Alyahya (742654)

“…Graph depicts the mean CFU value with standard deviation (n = 23, weeks 28 and 36). At all time points measured, no significant statistical differences were noted between the TV Ad35+ group, the vector control group, NC-V, and the main control group, NC-T4 (ANOVA) Boosting with Ad26-TBS at week 16 did not result in decreased bacterial burden by week 28 compared to all other groups in the study (p = 0.14, ANOVA)</p>…”

Asymmetric cell divisions can induce large cell-to-cell variability in mtDNA quality. by Robert C. Glastad (10692277)

“…The three columns for each panel give decreasing network heterogeneity, expressed via different seed numbers, 4, 16 and 64 (more seed points give a more homogeneous network). …”

TRPC channels modulate the vesicle replenishment rate and the RRP size. by Yvonne Schwarz (7406756)

“…<p>(A) Exemplary EPSCs triggered by HFS (20 Hz, 40 AP/2 s) of autaptic wt and TRPC1/C4/C5 tko neurons (inset magnified view on the first 4 EPSCs of the train response. …”

Shortened and disorganized growth plate in mice with disrupted BMP signaling. by Bettina Keller (231677)

“…<p>(A–C) Growth plate sections of long bones of P1 and (D–F) eight weeks old mice stained with Hematoxylin and Eosin. …”

Dependency of TGFβ effects on TER from the side of stimulation. by Angelika Stammler (483878)

“…<p>TGFβ3 was applied into the upper compartment (apical) only (A), into the lower compartment (basolateral) only (B), or into both (apical + basolateral), (C). …”

Depolarization suppresses OS gene expression. by Sarah Sundelacruz (375923)

“…<p>Expression of ALP (A) and BSP (B) decreased by Day 7 of OS differentiation in response to addition of 40–80 mM K⁺ (OS-40K, OS-60K, OS-80K) or 10 nM ouabain (OS-ouab). …”

Coherent rotation of cells confined in annular geometry. by S S Soumya (839061)

“…Simulations done on an annular shaped geometry with outer radius, <i>R</i> and thickness, <i>t</i> show that mean vorticity of system decreases with increase in number density as in the case of a circle. …”

Dysregulation of Autophagy Contributes to Anal Carcinogenesis by Evie H. Carchman (3195855)

“…These observations are consistent with autophagy being inhibited at a later stage in the autophagic process. In contrast, in high-grade dysplasia and SCC in the DMBA-treated K14E6/E7 mice, there were decreased levels of p62 with a continued increase in punctate LC3β expression by IF, while autophagolysosomes were seen on EM, consistent with the process of autophagy proceeded to completion. …”

DataSheet_1_Dietary disodium fumarate supplementation alleviates subacute ruminal acidosis (SARA)-induced liver damage by inhibiting pyroptosis via mitophagy-NLRP3 inflammasome pat... by Hongzhu Zhang (15650402)

“…The results showed that feeding a high-concentrate diet induced decreased rumen fluid pH and increased ruminal LPS. …”

Root Exudation of Phytochemicals in Arabidopsis Follows Specific Patterns That Are Developmentally Programmed and Correlate with Soil Microbial Functions by Jacqueline M. Chaparro (130585)

“…Cumulative secretion levels of sugars and sugar alcohols were higher in early time points and decreased through development. In contrast, the cumulative secretion levels of amino acids and phenolics increased over time. …”

Reduced Photoreceptor Heterogeneity Packing Index (HPi) in an Eye with Capillary Non-Perfusion Contiguous with the Foveal Avascular Zone (FAZ). by Peter L. Nesper (3625847)

“…(E) Spectral-domain optical coherence tomography (SD-OCT) registered to the IR image showing the retinal area covered by the AOSLO montage. B-scan shows focal points where inner segment / outer segment junction is interrupted with decreased intensity of the outer segment / retinal pigment epithelium junction. …”

Data_Sheet_1_Profiling of Protein Degraders in Cultures of Human Gut Microbiota.xlsx by Alberto Amaretti (6938792)

“…<p>Unabsorbed proteins reach the colon and are fermented by the microbiota, yielding a variety of harmful metabolites. In the present study, a 16S rRNA gene survey identified the bacterial taxa flourishing in 11 batch fermentations with proteins and peptones as the sole fermentable substrates, inoculated with the feces of six healthy adults. …”

Image 1_Critical period plasticity is associated with resilience to short unpredictable stress.png by Robert Williams (80038)

“…All three groups of mice showed a mild increase in locomotor activity after stress, suggesting that the quality of plasticity does not correlate with resilience to anxiety-like phenotypes. …”

Cesarean section and association with intelligence quotient in adolescents: contribution from the RPS Cohort Consortium (Ribeirão Preto, Pelotas and São Luís), Brazil by Alice Bianca Santana Lima (15057786)

“…To control confounding factors, a theoretical model was elaborated using the directed acyclic graph. …”

Data_Sheet_3_Profiling of Protein Degraders in Cultures of Human Gut Microbiota.docx by Alberto Amaretti (6938792)

“…<p>Unabsorbed proteins reach the colon and are fermented by the microbiota, yielding a variety of harmful metabolites. In the present study, a 16S rRNA gene survey identified the bacterial taxa flourishing in 11 batch fermentations with proteins and peptones as the sole fermentable substrates, inoculated with the feces of six healthy adults. …”