3D neurospheres respond to known excitatory and inhibitory reference compounds. by Grace Woodruff (255718)

“…Each point represents an individual well with three wells per treatment. …”

Addition of ARPP-21 into the signaling network confers input-order constraint. by Anu G. Nair (461390)

“…The vertical red dotted line marks the start of calcium input. (E) The mean (solid black line) of normalized pSubstrate activation area and associated standard deviation (shaded grey region) produced by two fold increase or decrease in individual parameter values, one at a time. …”

Figure S1 - Hematological Changes in Women and Infants Exposed to an AZT-Containing Regimen for Prevention of Mother-to-Child-Transmission of HIV in Tanzania by Judith Ziske (181686)

“…At delivery, sample sizes were n≥30 (group 1-women) and n≥54 (group 2 women); at one month post-delivery, sample sizes were n≥39 (group 1-women) and n≥26 (group 2-women). A. A decrease and a subsequent increase in hemoglobin values was shown in group 1- women. …”

Down-regulation of IRP1 expression and IRP1 activities in mouse macrophages exposed to paraquat (PQ). by Anna Milczarek (4036724)

“…RAW 264.7 cells were treated for 2h with 500 μM PQ as described in Materials and methods. At indicated time-points after PQ withdrawal, cells were harvested and cytoslic extracts were prepared as described previously [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0176800#pone.0176800.ref055" target="_blank">55</a>]. …”

Image_1_Circadian and Seasonal Patterns of Body Temperature in Arctic Migratory and Temperate Non-migratory Geese.pdf by Götz Eichhorn (363616)

“…Although our data corroborated findings of a decrease in daily mean Tb before autumn migration in both migratory populations in this study, the pre-migratory decrease in Tb was less drastic than previously reported. …”

Image_1_Circadian and Seasonal Patterns of Body Temperature in Arctic Migratory and Temperate Non-migratory Geese.pdf by Götz Eichhorn (363616)

“…Although our data corroborated findings of a decrease in daily mean Tb before autumn migration in both migratory populations in this study, the pre-migratory decrease in Tb was less drastic than previously reported. …”

NUP-1 is necessary for cell growth and maintenance of nuclear architecture. by Kelly N. DuBois (176072)

“…<p>NUP-1 RNAi was induced in both BSF and PCF cells. (A, B) NUP-1 mRNA was depleted by ∼30% as measured by qRT-PCR normalized to β-tubulin, corresponding to a ∼75% decrease in NUP-1 protein after 24 h of RNAi induction. …”

CPZ pretreatment inhibits cleaved caspase-3 expression in rat brains after ethanol exposure. by Jing Wu (54032)

“…<p>(A) The diagram shows the cross section of the cerebrum, and the regions of the parietal cortex and CA1 of hippocampus are pointed out. …”

The morphogenesis and development of VM dopaminergic neurons is disturbed in <i>Dkk1^{<b>−/−</b>}</i> embryos. by Diogo Ribeiro (230483)

“…(B) Immunohistochemistry for TH in midbrain sections of <i>Dkk1^−/−</i> embryos revealed a decrease of aberrantly distributed dopaminergic neurons (upper panels) or an almost absence of dopaminergic neurons (bottom panels). …”

Emodin suppresses HG-induced cFLIP generation but not repressing its activation and increasing degration. by Junjie Gao (545578)

“…<p>(<b>a, b</b>) MCs were cultured in HG media and treated with 50 μM emodin for indicated times. …”

Status of peritubular myoid cells in <i>Wt1</i>^SC-cKO testis during fetal mouse testis development. by Qing Wen (808516)

“…Each bar is a mean±SEM of <i>n</i> = 3 mice. *, <i>P</i><0.05; **, <i>P</i><0.01.…”

Impact of inactivation of ependymin in dominant and subdominant zebrafish. by Lynne U. Sneddon (225482)

“…The dominant injected with antisera (AntiB) exhibited a significant decrease in aggression (*P = 0.023). …”

Statins reduce thrombus burden in non-stasis murine DVT. by Chase W. Kessinger (470740)

“…Representative H&E axial sections showed a decrease in luminal thrombosis area in atorvastatin-treated animals compared to PBS (<b>D, E</b>). …”

Activity of metalloproteinases in the adult gerbil hippocampus after global ischemia. by Luiza Wójcik-Stanaszek (347531)

“…Confocal photomicrographs showing <i>in situ</i> zymography in DG and CA1 from a control animal (A, E) and from ischemic animals sacrificed at 7 (B, F), 14 (C, G) and 28 days (D, H) after ischemia. …”

Effect of synergistic antimicrobial combinations on growth kinetics of MDR pathogens. by Amber Farooqui (315564)

“…Control organisms were grown in MH broth only. A 2Log₁₀ decrease at any time point from original CFU was considered as significant. …”

Data_Sheet_5_DNA Methylation Is Responsive to the Environment and Regulates the Expression of Biosynthetic Gene Clusters, Metabolite Production, and Virulence in Fusarium graminear... by Christopher Bonner (9990611)

“…In this study, we characterized two DNMTs (FgDIM-2 and FgRID) in F. graminearum, with homologies to “Deficient in methylation” (DIM-2) and “Repeat-induced point (RIP) deficient” (RID) from Neurospora. The loss of DNMTs resulted in not only a decrease in average methylation density in the nutrient-poor, compared to nutrient-rich conditions, but also differences in the genes expressed between the WT and the DNMT mutant strains, implicating the external environment as an important trigger in altering DNA methylation patterns. …”

Data_Sheet_2_DNA Methylation Is Responsive to the Environment and Regulates the Expression of Biosynthetic Gene Clusters, Metabolite Production, and Virulence in Fusarium graminear... by Christopher Bonner (9990611)

“…In this study, we characterized two DNMTs (FgDIM-2 and FgRID) in F. graminearum, with homologies to “Deficient in methylation” (DIM-2) and “Repeat-induced point (RIP) deficient” (RID) from Neurospora. The loss of DNMTs resulted in not only a decrease in average methylation density in the nutrient-poor, compared to nutrient-rich conditions, but also differences in the genes expressed between the WT and the DNMT mutant strains, implicating the external environment as an important trigger in altering DNA methylation patterns. …”

Storage volume and water level fluctuations change across seasons. by Philipp Emanuel Hirsch (676010)

“…Accordingly, if columns point below the zero isocline, they constitute a decrease in water level. …”

Data_Sheet_4_DNA Methylation Is Responsive to the Environment and Regulates the Expression of Biosynthetic Gene Clusters, Metabolite Production, and Virulence in Fusarium graminear... by Christopher Bonner (9990611)

“…In this study, we characterized two DNMTs (FgDIM-2 and FgRID) in F. graminearum, with homologies to “Deficient in methylation” (DIM-2) and “Repeat-induced point (RIP) deficient” (RID) from Neurospora. The loss of DNMTs resulted in not only a decrease in average methylation density in the nutrient-poor, compared to nutrient-rich conditions, but also differences in the genes expressed between the WT and the DNMT mutant strains, implicating the external environment as an important trigger in altering DNA methylation patterns. …”

Specialization of Gene Expression during Mouse Brain Development by Noa Liscovitch (108538)

“…Surprisingly, we found that during the time that the brain becomes anatomically regionalized in early development, transcription specialization actually decreases reaching a low, “neurotypic”, point around birth. …”