Factors affecting cumulative systemic damage. by Alexander D. Malkin (813998)

“…<p><b>(A)</b> Cumulative damage seen in survivors and non-survivors. …”

PTX inhibits RTEF-1 driven endothelial cell aggregation and migration. by Ping He (33281)

“…<p><b>A.</b> PTX decreased RTEF-1 driven endothelial cell tube formation and aggregation. …”

Reproductive parameters of compound heterozygous mutant mice. by Elizabeth Snyder (304276)

“…<p>(A) Body weight and (B) testis weight remained unchanged, while (C) epididymal sperm count is significantly decreased in compound heterozygous relative to single heterozygous (<i>Ybx2</i>^+/- or <i>Ybx3</i> ^+/-) or wildtype mice. …”

Burden and trend of diet-related non-communicable diseases in Australia and comparison with 34 OECD countries, 1990-2015: findings from the Global Burden of Disease Study 2015. by Melaku, Yohannes Adama

“…Young (25-49 years) and middle-age (50-69 years) male adults had a higher PAF of diet-related NCD deaths and DALYs than their female counterparts. …”
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Membrane currents and evoked calcium transients. by Saju Balakrishnan (58265)

“…<p><b><i>A</i>–</b>Sample HCN and calcium currents evoked by voltage steps to -50 and -110 mV, respectively, from the holding potential -70 mV, close to the measured resting potential. …”

Key model formula. by Chayanit Mahasing (19688403)

“…In addition, we conducted a one-way sensitivity analysis by adjusting R0 from 1.8 to 3.0 in all scenarios (epidemic stage) and by decreasing the vaccination cost by 50% at the end of the first year to reflect the current policy direction to enhance domestic vaccine production. …”

Image_1_Reassessing Particulate Organic Carbon Dynamics in the Highly Disturbed San Francisco Bay Estuary.TIF by Peter J. Hernes (8640351)

“…Lignin compositional data (syringyl:vanillyl and cinnamyl:vanillyl) suggest that increased lignin content in the more saline samples could be derived from wetland materials, while a two-endmember mixing model indicates that a significant portion of the particulate organic carbon (POC) in the western sites (50–60% as an upper bound, 13–15% as a lower bound) could be wetland-derived. …”

Image_2_Reassessing Particulate Organic Carbon Dynamics in the Highly Disturbed San Francisco Bay Estuary.TIF by Peter J. Hernes (8640351)

“…Lignin compositional data (syringyl:vanillyl and cinnamyl:vanillyl) suggest that increased lignin content in the more saline samples could be derived from wetland materials, while a two-endmember mixing model indicates that a significant portion of the particulate organic carbon (POC) in the western sites (50–60% as an upper bound, 13–15% as a lower bound) could be wetland-derived. …”

Model framework. by Chayanit Mahasing (19688403)

“…In addition, we conducted a one-way sensitivity analysis by adjusting R0 from 1.8 to 3.0 in all scenarios (epidemic stage) and by decreasing the vaccination cost by 50% at the end of the first year to reflect the current policy direction to enhance domestic vaccine production. …”

Data_Sheet_1_The Enhancement of Intestinal Immunity in Offspring Piglets by Maternal Probiotic or Synbiotic Supplementation Is Associated With the Alteration of Gut Microbiota.pdf by Kai Wang (21246)

“…The results showed that plasma interleukin (IL)-2 and lipopolysaccharide concentrations were decreased (P < 0.05) in the probiotic group, while the immunoglobulin A (IgA) concentration in the probiotic and synbiotic groups was increased (P < 0.05), when compared with the control group. …”

Data Sheet 1_TP53 and KRAS co-mutations are associated with worse outcomes in mucinous ovarian carcinomas.docx by Yingao Zhang (10690941)

“…On multivariable analysis, TP53/KRAS co-mutations were associated with decreased PFS (adjusted hazard ratio [aHR] 4.02, 95% confidence interval [CI] 1.46-12.5, p=0.01) and OS (aHR 21.4, 95% CI 4.28-156, p<0.001). …”

Essential model parameters. by Chayanit Mahasing (19688403)

“…In addition, we conducted a one-way sensitivity analysis by adjusting R0 from 1.8 to 3.0 in all scenarios (epidemic stage) and by decreasing the vaccination cost by 50% at the end of the first year to reflect the current policy direction to enhance domestic vaccine production. …”

Mapping the Internal Recognition Surface of an Octanuclear Coordination Cage Using Guest Libraries by Simon Turega (1322268)

“…The highest association constant is <i>K</i> = 1.2 × 10⁶ M^–1 for cycloundecanone, whose volume is approximately 50% of the cavity volume; for larger C₁₂ and C₁₃ cyclic ketones, the association constant progressively decreases as the guests become too large. …”

Hydrogel Based 3-Dimensional (3D) System for Toxicity and High-Throughput (HTP) Analysis for Cultured Murine Ovarian Follicles by Hong Zhou (29614)

“…We observed partial follicle survival of 35% ± 3% (n = 80) in 0.01nM treatment and 48% ± 2% (n = 92) in 0.005nM, which we identified as the IC50 for secondary follicles. In summary, we established a 3D <i>in vitro</i> ovarian follicle culture system that could be used in an HTP approach to measure toxic effects on ovarian follicles.…”

Notch signalling is required for appropriate neurulation. by Heather Main (411912)

“…Scale bar is 50 μm. Please see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0062959#pone.0062959.s001" target="_blank">Fig. …”

S1 Graphical abstract - by Eduardo J. Aguilar-Rangel (18349662)

“…While the <i>amoA</i>-AOA: <i>amoA</i>-AOB ratio decreased from 9.8 in rainfed soils to 1.6 in soils irrigated for 100 years, indicating a favoring environment for AOB rather than AOA. …”

Co-delivery of free vancomycin and transcription factor decoy-nanostructured lipid carriers can enhance inhibition of methicillin resistant <i>Staphylococcus aureus</i> (MRSA) by Alan Hibbitts (6818348)

“…However, co-delivery of cNLC-TFD with vancomycin reduced the MIC of vancomycin by over 50% in MSSA and resulted in significant decreases in viability compared with vancomycin alone in MRSA cultures. …”

Relevance of Baseline Viral Genetic Heterogeneity and Host Factors for Treatment Outcome Prediction in Hepatitis C Virus 1b-Infected Patients by Verónica Saludes (236184)

“…</p><p>Principal Findings</p><p>A multivariate discriminant predictive model was generated including the following variables in decreasing order of significance: the number of viral variants in the E1–E2 region, an amino acid substitution pattern in the viral core region, the <i>IL28B</i> polymorphism, serum GGT and ALT levels, and viral load. …”

Determination of gene expression signature for high microglia/macrophage infiltrate and association with cell-specific gene signatures and molecular subtypes. by Jane R. Engler (140558)

“…Each dot represents an individual patient tumor, red denotes tumors defined to have high numbers of microglia/macrophages (greater than 67.5 microglia/macrophages per 400× field), blue dots denote tumors defined to have low microglia/macrophage numbers (less than 44.6 microglia/macrophages per 400× field). A representative image of microglia/macrophage staining (Iba1) for each group is shown (scale bars = 50 µm). …”

Table_1_Oxidative balance score was negatively associated with the risk of metabolic syndrome, metabolic syndrome severity, and all-cause mortality of patients with metabolic syndr... by Zhixiao Xu (3469277)

“…</p>Results<p>After multivariable adjustment, individuals with elevated OBS were found to exhibit a decreased susceptibility to MetS [odds ratio (OR) 0.95; 95% CI 0.94-0.96]. …”