Constitutive recruitment to the chromatin of truncated AR protein and transcription of AR responsive genes are impaired by the Y267F mutation. by Mehmet Karaca (4365)

“…The score from two independent samples is shown. A positive score indicates increased activation of the AR transcription pathway while a negative score indicates decreased activation of the pathway.…”

Characterization of macrophage phenotype in <i>Sgpl1^+/+</i> transplanted mice versus <i>Sgpl1^−/−</i> chimeras. by Martine Bot (585909)

“…<p>Gene expression analysis of bone marrow derived macrophages indicated a generally pro-inflammatory phenotype of <i>Sgpl1^−/−</i> macrophages as judged by the increased expression of the markers IL-6 (A), TNF-α (B), IL-1α (C) and IL-12 (D), while in contrast iNOS expression, another marker of a pro-inflammatory “classically activated” macrophage was sharply decreased (E). …”

The Spatial Dynamics of Dengue Virus in Kamphaeng Phet, Thailand by Piraya Bhoomiboonchoo (628511)

“…Significant clustering was observed up to 5 km. We found a steadily decreasing trend in the correlation in epidemics curves by distance: communities separated by up to 5 km had a mean correlation of 0.28 falling to 0.16 for communities separated between 20 km and 25 km. …”

The psychosocial impact of leg ulcers in patients with sickle cell disease: I don’t want them to know my little secret by Nkeiruka I. Umeh (4521403)

“…Major themes identified included:1) pain (acute and chronic); 2) compromised physical function as demonstrated by decreased ability to walk, run, and play sports; 3) social isolation from activities either by others or self-induced as a means of avoiding certain emotions, such as embarrassment; 4) social relationships (family support and social network); 5) support and comfort through their religion or spirituality.…”

Image 6_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.tif by Ilmari Pyykkö (2855153)

“…The study population comprised 79.5% females and 20.5% males, with a mean age of 63 years and an average disease duration of 15.2 years.…”

Normalisation against Circadian and Age-Related Disturbances Enables Robust Detection of Gene Expression Changes in Liver of Aged Mice by Sara S. Fonseca Costa (3626267)

“…Using the geometric mean of expression of the genes to normalise Nanostring hybridization experiments we reliably identified age-related increases in the expression of <i>Casein kinase 1δ</i> and <i>1ϵ</i>, and <i>Sfpq</i>, while the expression of the glucose transporter <i>Glut2</i> decreased. …”

Image1_Clinical presentation and transmission of postnatal cytomegalovirus infection in preterm infants.tif by Jun Eon Lee (14145270)

“…A comparison between the median CMV load in breast milk from the pCMV and control groups revealed a significant difference (P = 0.043).…”

Image 4_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.tif by Ilmari Pyykkö (2855153)

“…The study population comprised 79.5% females and 20.5% males, with a mean age of 63 years and an average disease duration of 15.2 years.…”

Image 5_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.tif by Ilmari Pyykkö (2855153)

“…The study population comprised 79.5% females and 20.5% males, with a mean age of 63 years and an average disease duration of 15.2 years.…”

Circulating Endothelial Progenitor Cells in Kidney Transplant Patients by Giovana S. Di Marco (206524)

“…Indeed, multivariate analysis showed that SDF-1 – a cytokine responsible for EPC mobilization – is independently associated with the EPC number. 5/6 rats presented decreased EPC counts in comparison to control animals. …”

Table 1_Association between the composite dietary antioxidant index and cardiovascular-kidney-metabolic syndrome among U.S. adults: evidence from NHANES 2007–2018.docx by Qiuming He (1707253)

“…</p>Results<p>This study included 11,073 adults aged 20 years and older, with a mean age of 48 years and a gender distribution of 52.75% female and 47.25% male. …”

Image 1_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.tif by Ilmari Pyykkö (2855153)

“…The study population comprised 79.5% females and 20.5% males, with a mean age of 63 years and an average disease duration of 15.2 years.…”

Inhibition of RLC <i>Myl9</i> or its upstream kinases ROCK or MLCK results in defective palatal fusion. by Seungil Kim (717948)

“…<p>(A–D) siRNA knockdown of <i>Myl9</i> resulted in significantly reduced palatal fusion (B, C) compared with control (scrambled RNA transfected) (A, C) in explants cultured for 72 h. …”

Image 2_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.tif by Ilmari Pyykkö (2855153)

“…The study population comprised 79.5% females and 20.5% males, with a mean age of 63 years and an average disease duration of 15.2 years.…”

Possible interactions between <i>Dimm</i> and <i>dInR</i> in ABLKs and effects on nuclear size. by Jiangnan Luo (218899)

“…<b>G</b> The total fluorescence (mean fluorescence multiplied by cell size) in abdominal DIMM immunolabeled neurons decreases with dInR-RNAi, but there is no significant increase after dInR over expression (*p<0.05, **p<0.01, n = 8 animals for each genotype from 3 crosses; unpaired Student's T-test). …”

Data Sheet 1_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.pdf by Ilmari Pyykkö (2855153)

“…The study population comprised 79.5% females and 20.5% males, with a mean age of 63 years and an average disease duration of 15.2 years.…”

JNK3-N-Tat attenuated the MPP^+/MPTP-induced activation of JNK3 by inhibiting the binding of β-arrestin2 to JNK3 following MPP⁺-induced injury. by Jing Pan (95938)

“…(B, D, F, H) Bar graphs display the results of our statistical analysis (mean±SD). NC: Normal control; N-Tat: JNK3-N-Tat; 4A-Tat: JNK3-4A-Tat. …”

Isomer-Specific Hexabromocyclododecane (HBCDD) Levels in Top Predator Fish from Across Canada and 36-Year Temporal Trends in Lake Ontario by Guanyong Su (1461877)

“…The greatest ratio was 20.8 in fish from Lake Ontario, whereas the lowest ratio was 6.3 for fish from Lac Memphrémagog (Québec) likely related to more recent emissions of a technical HBCDD mixture. Temporal trends of HBCDD in lake trout from Lake Ontario showed a significant decreasing trend for γ-HBCDD with a half-life estimate of 10 years over a 36-year period (1979–2015), and for α-HBCDD with a half-life of 11 years over the years of 2008 to 2015. …”

Supplementary Material for: Efficacy and safety of transdermal medical cannabis (THC:CBD: CBN formula) to treat painful diabetic peripheral neuropathy of the lower extremities by Seevathee K. (20196534)

“…Results: The intervention group demonstrated statistically significant reductions in NPSI-T scores across all measured dimensions (p<0.001). Mean total NPSI-T scores decreased markedly from 25.60 to 5.57 in the treatment cohort, contrasting with minimal reduction from 25.24 to 22.85 in the placebo group. …”

Isomer-Specific Hexabromocyclododecane (HBCDD) Levels in Top Predator Fish from Across Canada and 36-Year Temporal Trends in Lake Ontario by Guanyong Su (1461877)

“…The greatest ratio was 20.8 in fish from Lake Ontario, whereas the lowest ratio was 6.3 for fish from Lac Memphrémagog (Québec) likely related to more recent emissions of a technical HBCDD mixture. Temporal trends of HBCDD in lake trout from Lake Ontario showed a significant decreasing trend for γ-HBCDD with a half-life estimate of 10 years over a 36-year period (1979–2015), and for α-HBCDD with a half-life of 11 years over the years of 2008 to 2015. …”