<em>In Vivo</em> Imaging with Fluorescent Smart Probes to Assess Treatment Strategies for Acute Pancreatitis by Abhiruchi Agarwal (281215)

“…A dose dependent decrease of total pancreatic fluorescence signal occurred upon administration of known trypsin inhibitors. …”

Linear free energy relationships in RNA transesterification: theoretical models to aid experimental interpretations by Ming Huang (4181119)

“…As leaving group becomes more acidic and labile, the barriers of both early and late transition states decrease. LFERs for each transition state are computed, with the late transition state barrier showing greater sensitivity to leaving group pK<small>a</small>. …”

ORF63 does not affect STAT2 activation but promotes IRF9-degradation. by Marieke C. Verweij (357813)

“…The GAPDH signal was used a loading control. (B) TRFs were infected with AdORF63 at MOI 20 and AdTA at MOI 10 and simultaneously incubated with decreasing amounts of Dox. 48 hours p.i. the cells were stimulated with 5000 U/ml uIFN for 20 minutes, lysed and stained for IRF9, ORF63 and GAPDH. …”

Clathrin-independent hERG internalisation. by Rucha Karnik (504688)

“…<p>(A) The distribution of HA-hERG_hERG or HA-K_ATP transiently expressed in HeLa cells was compared after 30 minutes incubation with anti-HA in the presence or absence of 80 µM dynasore, 5 mM MβCD, 5 mM αCD or 15 µM/50 µM SecinH3. …”

Denervation induces an increase in excitatory synaptic strength. by Andreas Vlachos (47497)

“…The neuron was filled with biocytin and post-hoc identified using Alexa568-conjugated streptavidin (red; blue, TO-PRO nuclear stain). Scale bar: 50 µm. (<b>B</b>) Sample traces of miniature excitatory post synaptic currents (mEPSC) recordings from non-lesioned control cultures and from denervated granule cells at 4 dpl. …”

The Impact of Phenotypic and Genetic Heterogeneity on Results of Genome Wide Association Studies of Complex Diseases by Mirko Manchia (423673)

“…In both simulated and real data, heterogeneity (presence of “non-cases”) reduced the statistical power to detect genetic association and greatly decreased the estimates of risk attributed to genetic variation. …”

Optimization of Irreversible Electroporation Protocols for In-vivo Myocardial Decellularization by Yaniv Zager (3366920)

“…<div><p>Background</p><p>Irreversible electroporation (IRE) is a non-thermal cell ablation approach that induces selective damage to cell membranes only. …”

Dietary Protein Affects Gene Expression and Prevents Lipid Accumulation in the Liver in Mice by Jessica Schwarz (125436)

“…</p> <h3>Results</h3><p>Mice fed the HP diets displayed a lower body weight, developed less adiposity and decreased hepatic lipid accumulation, which could be attributed to a combination of several processes. …”

Fourier-transform infrared imaging spectroscopy and laser ablation -ICPMS new vistas for biochemical analyses of ischemic stroke in rat brain by Ali M.H.M.

“…Areas close to the stroke focus experienced decrease in the lipid and lipid acyl contents associated with an increase in lipid ester, olefin, and methyl bio-contents with a novel finding of A?…”
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Table1_Evaluation and clinical implications of interactions between compound Danshen dropping pill and warfarin associated with the epoxide hydrolase gene.DOCX by Xixi Chen (5749067)

“…<p>Introduction: In clinical practice, warfarin is often combined with Compound Danshen dripping pill (CDDP) for the treatment of cardiovascular diseases. However, warfarin has a narrow therapeutic index, wide interindividual variability (genetic and non-genetic factors), and is susceptible to drug-drug interactions. …”

Table_1_Swallowing sound evaluation using an electronic stethoscope and artificial intelligence analysis for patients with amyotrophic lateral sclerosis.docx by Masahiro Nakamori (490923)

“…In all cases, the mean swallowing sound index was 0.209 ± 0.088. A multivariate analysis showed that a decrease in the swallowing sound index was significantly associated with a low ALSFRS-R score, an ALSFRS-R bulbar symptom score, % vital capacity, tongue pressure, a Mann Assessment of Swallowing Ability (MASA) score, and a MASA pharyngeal phase-related score.…”

The effect of temperature and acidic pH stress on the <i>de novo</i> protein synthesis in <i>Leishmania</i>. by Serge Cloutier (160605)

“…Aliquots were taken at 1, 3, 5 and 24 hours and the radioactivity (in cpm) was measured by a scintillation counter. A decrease in cpm numbers corresponds to protein degradation under stress. …”

Data_Sheet_1_N6-Methyladenine in Eukaryotic DNA: Tissue Distribution, Early Embryo Development, and Neuronal Toxicity.PDF by Sara B. Fernandes (10860612)

“…Furthermore, exposure to a neurotoxic environmental pollutant during the same early life period may led to a decrease in the levels of this modification in female rats. …”

Higher egg consumption associated with increased risk of diabetes in Chinese adults - China Health and Nutrition Survey. by Wang, Yue

“…Egg consumption at each survey was assessed by a 3-d 24-h recall and weighed food record methods. …”
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Bond durability of sand coated and ribbed basalt FRP bars embedded in high-strength concrete by Al-Hamrani, Abathar

“…However, specimens with high-strength concrete achieved most of or above their maximum bond strength after the descending stage, while those with normal-strength concrete showed a decrease in bond strength to an approximately constant value with continuous slip. …”
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Effects of topiramate on pregnancy outcome in rats by Fadel, Raouf

“…Result: The Topiramate treated groups showed an insignificant increase in the rate of resorption, a significant decrease in umbilical cord length, placental weight and highly significant reduction in fetal growth parameters. …”
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Table_4_Comprehensive Genome-Wide Analysis of Thaumatin-Like Gene Family in Four Cotton Species and Functional Identification of GhTLP19 Involved in Regulating Tolerance to Vertici... by Zhanshuai Li (9539504)

“…GhTLP19 on chromosome At05 was selected as a candidate gene for further study. When GhTLP19 was silenced by virus-induced gene silencing (VIGS) in cotton, with the increase of malondialdehyde (MDA) content and the decrease of catalase (CAT) content, and as the increase of disease index (DI) and hyphae accumulation, the plants were more sensitive to drought and Verticillium dahliae. …”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”

Effect of OWB extract and CA on pro-inflammatory and anti-inflammatory cytokine release in LPS-induced peritoneal macrophages by sandwich ELISA and RT-PCR. by Durbadal Ojha (475076)

“…<p>Peritoneal macrophages were cultured overnight and incubated with LPS (1 µg/ml), washed after 4 h and then treated with the OWB (50 or 100 µg/m) or CA (10 µg/ml). The cells were further incubated for 24 h, and the cell-free supernatants were subjected to sandwich ELISA to determine the level of (A) TNF-α, (C) IL-1β, (E) IL-6 and (G) IL-6 (pg/mL). …”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”