A regulatory gene network of foam-cell formation. by Josefin Skogsberg (88384)

“…CE accumulation (given as average percentage next to each node) was decreased (blue) by siRNA inhibition of 5 genes and increased (red) by inhibition of 2 genes; inhibition of 1 gene had no effect (black) (see also <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000036#pgen-1000036-t003" target="_blank">Table 3</a>). …”

Esculetin, a coumarin derivative, exerts in vitro and in vivo antiproliferative activity against hepatocellular carcinoma by initiating a mitochondrial-dependent apoptosis pathway by J. Wang (472325)

“…Esculetin significantly inhibited proliferation of HCC cells in a concentration- and time-dependent manner and with an IC50 value of 2.24 mM. …”

Simulation results for a network with leftward shifted STDP. by Baktash Babadi (359969)

“…</b> The steady-state mean synaptic weight as a function of the initial rate. …”

Experimental Evolution of a Novel Sexually Antagonistic Allele by Rebecca Dean (109545)

“…In sexually reproducing organisms, sex-specific optima mean that the same allele can have sexually antagonistic expression, i.e. beneficial in one sex and detrimental in the other, a phenomenon known as intralocus sexual conflict. …”

Water immersion and one-year storage influence the germination of the pyrenes of Copernicia alba Morong, a palm tree from a neotropical wetland by Vanessa Couto Soares (14189614)

“…<div><p>ABSTRACT Palm seeds are known for displaying dormancy and a thick endocarp that delays germination and embryo growth, but water treatments may accelerate their germination process. …”

Measured Densities and Viscosities of High-Pressure Carbon Dioxide–Isopropanol Mixtures by Friday N. Abolorunke (20390812)

“…Density, which increases with CO₂ mass fraction until a maximum and then decreases to that of pure CO₂, was measured using 3 redundant methods, viz., a variable-volume cell with an expanded uncertainty (<i>k</i> = 2) of 2.0% of reading, a Coriolis meter with a vendor-specified accuracy of ±7 kg/m³, and, to verify selected data points, a “bomb” experiment with an expanded uncertainty (<i>k</i> = 2) of 1.0% of reading. …”

A Bioenergetic Basis for Membrane Divergence in Archaea and Bacteria by Víctor Sojo (613931)

“…Pumping protons across leaky membranes offers no advantage, even when permeability is decreased 1,000-fold. We hypothesize that a sodium-proton antiporter (SPAP) provided the first step towards modern membranes. …”

The role of actin filaments in recruitment of Rab5-positive endosomes to the large tombusviral replication compartments in plant cells. by Kai Xu (122914)

Tissue-Specificity of Gene Expression Diverges Slowly between Orthologs, and Rapidly between Paralogs - Fig 2 by Nadezda Kryuchkova-Mostacci (762717)

Distribution of tissue-specificity in paralogs compared to an outgroup ortholog. by Nadezda Kryuchkova-Mostacci (762717)

Temporal reproduction number. by Nicolas Franco (11629444)

<i>Vegfa</i> mRNA levels in intact skin and in granulation tissue in wild type and mutant (<i>Vegfa</i>^∂/∂) mice. by Domenic Ciarlillo (4233637)

Pbp1 regulates Puf3-target mRNA and protein levels. by Floortje van de Poll (15810877)

“…<p>A. A protein (Cox2) whose synthesis is dependent on Puf3-target mRNAs is decreased in <i>pbp1Δ</i> cells compared to WT. …”

Increased amounts of Puf3 interact with Pbp1 under respiratory conditions. by Floortje van de Poll (15810877)

“…<p>A. Only proteins whose synthesis is dependent on Puf3-target mRNAs (Cox2) are decreased in <i>puf3Δ</i>, <i>pbp1Δ</i>, and <i>pbp1Δpuf3Δ</i> cells as compared to WT. …”

A trend in discussions about the endemic blues and daily responsibilities. by Seoyoung Kim (2603596)

Photographs of the left eye before (A-E) and after (F-H) systemic corticosteroids therapy in a 39-year-old woman with AZOOR. by Saho Saito (731215)

“…<p>(A) Fundus photograph shows normal retinal appearance except for narrowing and tortuosity of the retinal arteries (arrowheads). …”

Reliability of a Newly-Developed Immunochromatography Diagnostic Kit for Pandemic Influenza A/H1N1pdm Virus: Implications for Drug Administration by Tadahiro Sasaki (114367)

“…<div><h3>Background</h3><p>For the diagnosis of seasonal influenza, clinicians rely on point-of-care testing (POCT) using commercially available kits developed against seasonal influenza viruses. …”

Healing kinetics and macroscopic appearance of wounds in wild type and <i>Vegfa</i>^∂/∂ mice. by Domenic Ciarlillo (4233637)

Effect of treatment with TSA on Aβ42 and Aβ40 levels in APPswe/PS1dE9 transgenic mice. by Li Shen (110858)

“…(A) Aβ40 was significantly decreased in two TSA-treated groups. …”

A279T inhibits proliferation of esophageal cancer cells. by Yuwei Zhang (388956)

“…Immunofluorescence analysis (left panel) with corresponding summary (right panel) of Ki67 expression in esophageal cancer cells expressing wtTERT or A279T (Red: Ki67; blue: DAPI). EsC1 and EsC2 cells expressing A279T exhibit decreased Ki67 levels relative to respective cells expressing wtTERT. …”