Table_1_Targeted Metabolomics Shows That the Level of Glutamine, Kynurenine, Acyl-Carnitines and Lysophosphatidylcholines Is Significantly Increased in the Aqueous Humor of Glaucom... by Alejandro Lillo (11666527)

“…The imbalance affects membrane components, especially those of the mitochondria, suggesting that mitochondrial abnormalities are a cause or consequence of glaucoma. The increase in glutamine in glaucoma is also relevant because it could be a means of keeping the concentration of glutamate under control, thus avoiding its potential to induce the death of neurons and retinal cells. …”

Changes in the Cell Viability of Tzb-refractory Cells Upon Pharmacological Modulation of Autophagosomes Formation/Function. by Alejandro Vazquez-Martin (75018)

“…The total number of LC3-positive autophagosomes per cell is notably decreased in 3-MA-treated TzbR cells. Images show representative portions of SKBR3 and TzbR cell cultures captured in different channels for LC3 (<i>red</i>) and Hoechst 33258 (<i>blue</i>) with a 20× objective, and merged on BD Pathway™ 855 Bioimager System using BD Attovision™ software. …”

Data_Sheet_1_Targeted Metabolomics Shows That the Level of Glutamine, Kynurenine, Acyl-Carnitines and Lysophosphatidylcholines Is Significantly Increased in the Aqueous Humor of Gl... by Alejandro Lillo (11666527)

“…The imbalance affects membrane components, especially those of the mitochondria, suggesting that mitochondrial abnormalities are a cause or consequence of glaucoma. The increase in glutamine in glaucoma is also relevant because it could be a means of keeping the concentration of glutamate under control, thus avoiding its potential to induce the death of neurons and retinal cells. …”

Table_1_Overexpression of the Transcription Factor AtLEC1 Significantly Improved the Lipid Content of Chlorella ellipsoidea.XLSX by Xiao Liu (65413)

“…By comparing the differentially expressed genes (DEGs) regulated by AtLEC1 in C. ellipsoidea and Arabidopsis, we observed that approximately 59% (95/160) of the genes related to lipid metabolism were upregulated in AtLEC1 transgenic Chlorella. Our research provides a means of increasing lipid content by introducing exogenous TF and presents a possible mechanism of AtLEC1 regulation of lipid accumulation in C. ellipsoidea.…”

Role of psychosocial status in predicting health-related quality of life at 1-year follow-up among newly diagnosed people living with HIV by Yunxiang Huang (7535135)

“…The trajectories of depression from baseline to 1-year follow-up were categorized into four groups: never (PHQ-9 < 10 at two time points), new-onset (PHQ-9 < 10 at baseline & PHQ-9 ≥ 10 at follow-up), recovered (PHQ-9 ≥ 10 at baseline & PHQ-9 < 10 at follow-up) and persistent depression (PHQ-9 ≥ 10 at two time points). …”

GSTA3 Attenuates Renal Interstitial Fibrosis by Inhibiting TGF-Beta-Induced Tubular Epithelial-Mesenchymal Transition and Fibronectin Expression - Fig 1 by Yun Xiao (14988)

“…Semiquantitative analysis of tubulointerstitial damages as the degree of interstitial collagen deposition and collagen I expression in the renal cortex of rats from each group. Data expressed as means±S.E. *p<0.05 vs. SHM. <b>B) Expression of α-SMA protein was increased and that of E-cadherin protein was decreased in renal cortex of UUO rats.…”

<i>In vitro</i> wound healing assay in normal and high glucose medium. by Daisuke Kido (4710143)

“…(B) The relative cell migration area of the DM group cultured in high glucose concentration (75 mM) was significantly decreased at 18 to 48 h. Data are presented as means ± SD. …”

UBE3C activates Wnt/β-catenin pathway. by Ji Ling Wen (689905)

“…<p>(A) Left, <i>UBE3C</i> overexpression in 786-O cells up-regulated c-MYC and cyclin D1 mRNA levels. …”

Progressive synaptic deficits in the Katnal2-KO hippocampus. by Ryeonghwa Kang (6793046)

“…<p>(A–D) Decreased CBVs in various brain regions of Katnal2-KO mice, including the hippocampus surrounded by lateral ventricles, as compared with WT mice (3 months). …”

Effects of experimental warming and CO₂ addition on tide pools. by Cascade J. B. Sorte (223319)

“…<p>(a) Effects of warming on tide pool temperatures depended on air temperature. …”

Isoflavone contents in <i>GmMYB29</i>-overexpressing and <i>GmMYB29</i>-silenced soybean hairy roots. by Shanshan Chu (103400)

“…<p>(A) Overexpression of <i>GmMYB29</i> leads to increased isoflavone content in soybean hairy roots. …”

Overexpression of <i>Nlu-miR-34</i> in LW strain induced the development towards SW BPHs by suppressing <i>NlInR1</i>. by Xinhai Ye (6857771)

“…<p>(A) The agomir-34 was injected into early third instar nymphs in LW strain, significantly increasing the <i>Nlu-miR-34</i> expression (<i>p</i> = 0.026). …”

The effects of intrathecal AMD3100 on the production of neuropeptides and pro-inflammatory cytokines, and cellular adhesion molecules in the ipsilateral L3-L5 spinal cord segment o... by Xin Luo (428648)

“…<p>Real time PCR revealed that intrathecal AMD3100 decreased mRNA level of SP (B) and increased mRNA level of AM (C) and ICAM (G), but did not affect mRNA levels of CGRP (A), TNF-α (D) and IL-1β (E), IL-6 (F), VCAM (H) or EAAT-2 (I) at hour 8 after the injection. …”

Alternation of RNA levels of synaptic proteins and dendritic spines in hTDP-43_WT homozygous mice. by Ya-Fei Xu (85380)

“…<p>(<b>A</b>) Compared with non-transgenic (NT) mice, the RNA levels of TDP-43 targets PSD-95, Bsn, GAP-43 and Syt7 are significantly decreased in TDP-43 homozygous mice, but not in TDP-43 hemizygous mice. …”

CDDO-Me (3 mg/kg) does not affect the body weight, fat mass or blood lipid profile of any group. by Kazuma Ogiso (11993634)

“…<p>A: Body weight over the duration of feeding and administration. …”

Downregulation of Bak confers resistance of MDA-MB-231 cells to Taxol. by Yanwei Luo (800463)

“…<p>(A) QPCR detection of Bak mRNA after siRNA transfection. …”

Proinflammatory cytokines in the liver. by Hyunseong Kim (670519)

“…<p>The proinflammatory cytokines and NO in the liver tissue from normal and CD25-depleted mice were measured by ELISA and the Griess method, respectively. The hepatic TNF (A), IL-6 (B) and NO levels (C) were decreased in the PLA2-treated group (APAP + PLA2) compared with the PBS-treated group (APAP). …”

Sequence of ERP Components Evoked by the Target and Mask by Antoine Del Cul (273035)

“…In the mask-subtracted data, these components appear to increase with SOA, which in reality means that the mask-induced activation (mask-evoked N1 and N2) decreases with SOA.…”

Regulation of MMP9 in human hippocampus with cocaine exposure. by Deborah C. Mash (81518)

“…Levels of MMP2 activity were unchanged. Data are means±SEM. **<i>p</i> = 0.01 (one-tailed t-test).…”

Beta cell-specific deletion of survivin. by Xiaohong Wu (147036)

“…<p>(a) Immunohistochemistry showing survivin deletion in pancreatic beta cells at P1 from RIPcre⁺survivin^fl/fl mice (original magnification, ×400). …”