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21441
Feasibility of Large-Scale Phosphoproteomics with Higher Energy Collisional Dissociation Fragmentation
Published 2010“…Reducing the target values from a standard of 30 000 to 5000 ions did not severely affect identification rates but did decrease identification and localization scores for phosphorylation sites. …”
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21442
Expression of STUB1DN mutants leads to the formation of protein aggregates.
Published 2019“…Cells were further incubated in the presence or absence of 10uM of MG-132 and 50nM of BafA for 6h. A) Cell extracts of proteins insoluble in increasing concentrations of SDS where filtered through a nitrocellulose membrane and trapped proteins were blotted with antibodies directed against ubiquitin, p62 and myc tag. …”
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21443
Feasibility of Large-Scale Phosphoproteomics with Higher Energy Collisional Dissociation Fragmentation
Published 2010“…Reducing the target values from a standard of 30 000 to 5000 ions did not severely affect identification rates but did decrease identification and localization scores for phosphorylation sites. …”
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21444
Simultaneous PreCaT and extracellular field potential recordings.
Published 2014“…Effects of application of a cocktail of antagonists of ionotropic glutamate and GABA receptors ((2R)-amino-5-phosphonovaleric acid (APV, 50 µM); 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxaline-2,3-dione (NBXQ, 10 µM)) are also shown. …”
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21445
Female motorcycle mortality in Brazilian municipalities, 2005, 2010 and 2015
Published 2021“…In the municipalities of the South and Southeast regions, mainly in the period between 2010 and 2015, there was an apparent decrease in mortality. The percentage variation showed a reduction in the indicator analyzed in the period between 2010 and 2015 for the largest municipalities in the South and Southeast regions. …”
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21446
Neutralization by PGT121-137 antibodies and chimeric variants.
Published 2013“…<p>Strong neutralization is coded in red (>90%), intermediate in yellow (75–90%) and weak in green (50–75%). Neutralization data were generated in single neutralization experiments, with each test sample analyzed in duplicate to determine the percent decrease in virus growth (neutralization) as compared and normalized to the control wells without antibody expression (defined as 0% neutralization). …”
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21447
Schematic of the filtration setup and flowmeter device used in this study.
Published 2024“…<p>We used overpressure filtration for plankton size-class filtration with three filters in series, (<i>i</i>) a 180-μm nylon net pre-filter to remove zooplankton and larger particles, and (<i>ii</i>) a 5.0-μm and (<i>iii</i>) a 0.2-μm pore-size polycarbonate membrane filter, in order to collect the nanoplankton and picoplankton, respectively, for DNA extraction. …”
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21448
Data presented in the paper "Consumer and host body size effects on the removal of trematode cercariae by ambient communities"
Published 2019“…One individual was The effect of dilutor size on removal rates of cercariae was investigated in laboratory experiments by determining removal rates of five size categories of each dilutor species (Table 1). In addition, a sixth treatment without dilutors served as a control to account for potential loses of cercariae due other factors (knowing the number of added cercariae was 50) and to test for the presence of a dilution effect (control vs. dilutor size treatments). …”
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21449
Data_Sheet_1_Molybdenum and Cadmium Co-induce Mitochondrial Quality Control Disorder via FUNDC1-Mediated Mitophagy in Sheep Kidney.doc
Published 2022“…Forty-eight 2-month-old sheep were stochastically divided into four groups, as shown below: control group, Mo [45 mg/kg body weight (BW)] group, Cd (1 mg/kg BW) group and Mo (45 mg/kg BW)+Cd (1 mg/kg BW) group, with 50 days feed technique. The results showed that Mo or/and Cd attract an unbalance of trace minerals and vacuoles and granular degeneration of renal tubular epithelial cells, and increase the number of mitophagosomes and vacuole-mitochondria and LC3 puncta and MDA and H<sub>2</sub>O<sub>2</sub> contents, and decrease ATP content in the kidney. …”
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21450
Red Blood Cell Transfusion and Mortality in Trauma Patients: Risk-Stratified Analysis of an Observational Study
Published 2015“…Transfusion was associated with an increase in all-cause mortality among patients with <6% and 6%–20% predicted risk of death (odds ratio [OR] 5.40, 95% CI 4.08–7.13, <i>p<</i>0.0001, and OR 2.31, 95% CI 1.96–2.73, <i>p<</i>0.0001, respectively), but with a decrease in all-cause mortality in patients with >50% predicted risk of death (OR 0.59, 95% CI 0.47–0.74, <i>p<</i>0.0001). …”
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21451
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21452
Equilibrium binding of single strand DNA (P1) from promoter with mNdK
Published 2011“…CD spectra of P1 (4 μM) shows decrease in ellipticity at 285 nm with increasing mNdK (0–0.5 μM) in 50 mM Tris-MES-acetate pH 6.5, 1 mM MgCl, 75 mM NaCl within 30 min of incubation, after each addition, at 37°C. () Enzymatic (phosphotransfer) activity of mNdK at pH 6.5. …”
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21453
HepR21 cells have increased resilience to nutrient deprivation compared to HepG2 cells.
Published 2014“…A set of cells were kept as control. The survivability of HepR21 cells was found to remain unaffected while HepG2 cells were highly sensitive upon prolonged starvation with an overall 50% decrease in growth after 36 h of starvation. …”
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21454
Glyphosate affects the oxidative properties of melanogenesis.
Published 2021“…Glyphosate shifts Peak 1 and 2 toward a decreased redox potential and diminishes the current of Peak 1 and 2 in a dose-dependent manner (<b>H</b>), notably decreasing Peak 2 current intensity to the point of nonexistence <b>(I)</b>. …”
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21455
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21456
IL6/STAT3 modulates estrogen-induced GREB1 transcriptional activity in breast cancer cells.
Published 2013“…<p>E2 treatment increases GREB1 mRNA levels by approximately 43-fold after 48 h treatment (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046410#pone-0046410-g005" target="_blank">Figure 5A</a>). …”
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21457
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21458
Mechanism and kinetics of electrochemical degradation of uric acid using conductive-diamond anodes
Published 2016“…Results show that the increase of current density from 20 to 60 mA cm–2 leads to a decrease in the efficiency of the electrochemical process. …”
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21459
Predictive validity.
Published 2023“…Simulations last 500 ms with a time resolution of 0.1 ms and <i>υ</i>drive is a step at 50 Hz lasting 250 ms starting at 125 ms. …”
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21460
Video_1_Robustness and Scalability of Regional Climate Projections Over Europe.mp4
Published 2019“…<p>Climate change projections for Europe consistently indicate a future decrease in summer precipitation over southern Europe and an increase over northern Europe. …”