Effect of OWB extract and CA on pro-inflammatory and anti-inflammatory cytokine release in LPS-induced peritoneal macrophages by sandwich ELISA and RT-PCR. by Durbadal Ojha (475076)

“…<p>Peritoneal macrophages were cultured overnight and incubated with LPS (1 µg/ml), washed after 4 h and then treated with the OWB (50 or 100 µg/m) or CA (10 µg/ml). The cells were further incubated for 24 h, and the cell-free supernatants were subjected to sandwich ELISA to determine the level of (A) TNF-α, (C) IL-1β, (E) IL-6 and (G) IL-6 (pg/mL). …”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”

Image_4_Comprehensive Genome-Wide Analysis of Thaumatin-Like Gene Family in Four Cotton Species and Functional Identification of GhTLP19 Involved in Regulating Tolerance to Vertici... by Zhanshuai Li (9539504)

“…GhTLP19 on chromosome At05 was selected as a candidate gene for further study. When GhTLP19 was silenced by virus-induced gene silencing (VIGS) in cotton, with the increase of malondialdehyde (MDA) content and the decrease of catalase (CAT) content, and as the increase of disease index (DI) and hyphae accumulation, the plants were more sensitive to drought and Verticillium dahliae. …”

The Effect of Ligand Lipophilicity on the Nanoparticle Encapsulation of Pt(IV) Prodrugs by Timothy C. Johnstone (1312911)

“…As the platinum concentration was increased, there was an initial increase in encapsulation followed by a decrease due to macroscopic precipitation. Maximal loading occurred when the platinum complex was present at a 40% w/w ratio with respect to polymer during the nanoprecipitation step. …”

Genetic evaluation of growth in Polled Nellore via multi-trait models by Isabella Coutinho de Barros (5939096)

“…Unlikely, a decrease was observed from W205 to W365 for the maternal permanent environmental effect. …”

Image_2_Comprehensive Genome-Wide Analysis of Thaumatin-Like Gene Family in Four Cotton Species and Functional Identification of GhTLP19 Involved in Regulating Tolerance to Vertici... by Zhanshuai Li (9539504)

“…GhTLP19 on chromosome At05 was selected as a candidate gene for further study. When GhTLP19 was silenced by virus-induced gene silencing (VIGS) in cotton, with the increase of malondialdehyde (MDA) content and the decrease of catalase (CAT) content, and as the increase of disease index (DI) and hyphae accumulation, the plants were more sensitive to drought and Verticillium dahliae. …”

Mitochondrial Ca²⁺ uptake in permeabilized H295R cells transfected with <i>OPA1</i> or <i>Mfn1</i> siRNA. by László Fülöp (203208)

“…On day 5 the cells were permeabilized, superfused with a cytosol-like medium, Ψ_m was dissipated with 10 µM rotenon, 8 µg/ml oligomycin, 10 µM FCCP and 50 ng/ml valinomycin for 2 minutes. …”

3BrP effect on glycolytic enzymes as well as on differentiation markers assessed via embryoid body (EB) formation. by Ana Sofia Rodrigues (491559)

“…<p>ESCs were maintained in control conditions (with LIF), in the absence of LIF (differentiation control) and in the presence of two different 3BrP concentrations (25 and 50 μM) plus LIF. <b>A)</b>- Left: Protein levels for Hexokinases II and I, Gapdh and PDH were determined by Western Blot and quantified by densiometric evaluation. …”

Actively station: Effects on global cognition of mature adults and healthy elderly program using eletronic games by Tiago Nascimento Ordonez (6128363)

“…Results: The cognitive performance of the TG improved significantly after the program, particularly in the domains of language and memory, and there was a decrease on the anxiety index and frequency of memory complaints, when compared to the CG. …”

Table_2_Comprehensive Genome-Wide Analysis of Thaumatin-Like Gene Family in Four Cotton Species and Functional Identification of GhTLP19 Involved in Regulating Tolerance to Vertici... by Zhanshuai Li (9539504)

“…GhTLP19 on chromosome At05 was selected as a candidate gene for further study. When GhTLP19 was silenced by virus-induced gene silencing (VIGS) in cotton, with the increase of malondialdehyde (MDA) content and the decrease of catalase (CAT) content, and as the increase of disease index (DI) and hyphae accumulation, the plants were more sensitive to drought and Verticillium dahliae. …”

AP-1 knockdown potentiates the effect of AP-3 knockdown on regulated secretion. by Daniel W. Sirkis (463685)

“…<p>(A) PC12 cells were transfected with pooled siRNA directed against AP-1 γ or pooled nontargeting siRNA as control. …”

Image_3_Comprehensive Genome-Wide Analysis of Thaumatin-Like Gene Family in Four Cotton Species and Functional Identification of GhTLP19 Involved in Regulating Tolerance to Vertici... by Zhanshuai Li (9539504)

“…GhTLP19 on chromosome At05 was selected as a candidate gene for further study. When GhTLP19 was silenced by virus-induced gene silencing (VIGS) in cotton, with the increase of malondialdehyde (MDA) content and the decrease of catalase (CAT) content, and as the increase of disease index (DI) and hyphae accumulation, the plants were more sensitive to drought and Verticillium dahliae. …”

Discovery of Novel Celastrol Derivatives as Hsp90–Cdc37 Interaction Disruptors with Antitumor Activity by Na Li (6550)

“…Among all the target compounds, <b>41</b> was screened with superior antiproliferative activity on related cancer cells (IC₅₀: 0.41–0.94 μM) and <b>41</b> could decrease the level of the Hsp90–Cdc37 complex in A549 cells. …”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”

Dental pain prevalence among health care personnel by Ludmilla Awad Barcellos (10477586)

“…<div><p>ABSTRACT BACKGROUND AND OBJECTIVES: Dental pain is a major reason for looking for dental services. …”

MMR activities in the APE and hMSH6 expressing cells by In-Youb Chang (10654)

“…The repair efficiency was calculated as the percentage of decrease in the mixed-color colonies. The values are a mean ± SD from three separate experiments. …”

Effects of variation in pDC number and activation status. by Gennady Bocharov (67777)

“…<p>(A) Virus kinetics in spleen following infection with low (5×10¹ pfu), intermediate (5×10³ pfu) and high (5×10⁵ pfu) dose infections under conditions of varying pDC numbers per spleen. …”

Datasheet1_Trends in hypertension and hypertension treatment in primary care in general practices in Germany between 2013 and 2022.pdf by Karel Kostev (2577346)

“…After adjusting for covariates, there was a significant decrease in the number of patients diagnosed with hypertension (beta coefficient = −7.91, p-value < 0.001) and treated with any antihypertensive drug per practice per year between 2013 and 2022 (beta coefficient = −5.40, p-value < 0.001).…”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”