Genome-wide CRISPRi screen to reveal proteins and pathways impacting PF8503 toxicity in K562 cells. by Nadège Liaud (6470615)

“…<p>(A) Overview of the CRISPRi experiment, carried out using K562 cell lines expressing dCas-KRAB and the hCRISPRi-v2 library. …”

DataSheet1_Optimizing control strategies for urine nitrification: narrow pH control band enhances process stability and reduces nitrous oxide emissions.PDF by Valentin Faust (13176389)

“…To address the need for a robust and reliable process in decentralized applications, two different strategies were tested: operating a two-position pH controller (inflow on/off) with a narrow pH control band at 6.20/6.25 (∆pH = 0.05, narrow-pH) vs. a wider pH control band at 6.00/6.50 (∆pH = 0.50, wide-pH). …”

Table_2_Area Not Geographic Isolation Mediates Biodiversity Responses of Alpine Refugia to Climate Change.pdf by Jared D. Huxley (10678326)

“…Specifically, we found an increase in species richness, a trend toward increased phylogenetic diversity, a shift toward leaf traits associated with the stress-tolerant end of leaf economics spectrum (e.g., lower specific leaf area, higher leaf dry matter content), and a decrease in the functional dispersion of specific leaf area. …”

The Nutrient Network is a globally-distributed experiment testing top-down and bottom-up controls over grassland diversity and ecosystem function. by Lydia R. O’Halloran (284858)

“…<p>Our nested hierarchical analysis quantified variability for aboveground biomass and litter disappearance for 39 sites among continents, regions (i.e., among sites in the continental US, shown as filled points with colored circles), sites, blocks within sites (each with 1–6 blocks of 8–10 plots per block), and plots within blocks. …”

Continuum of phenotypic parallelism. by Arne Jacobs (3281970)

“…<p>(<b>A</b>) Principal components plot based on all seven linear traits showing the centroid ± s.e. for each ecotype (N = 1,329 individuals), with centroids of sympatric ecotypes connected by trajectories. …”

Data_Sheet_1_The Impact of the COVID-19 Pandemic on Smoking Consumption: A Systematic Review of Longitudinal Studies.DOCX by Nerea Almeda (6335807)

“…A total of 58,052 participants were included in the review. Most of the studies pointed out a reduction in the number of cigarettes and e-cigarettes consumed from baseline (before the pandemic) to follow-up (during the pandemic). …”

Table_1_Area Not Geographic Isolation Mediates Biodiversity Responses of Alpine Refugia to Climate Change.pdf by Jared D. Huxley (10678326)

“…Specifically, we found an increase in species richness, a trend toward increased phylogenetic diversity, a shift toward leaf traits associated with the stress-tolerant end of leaf economics spectrum (e.g., lower specific leaf area, higher leaf dry matter content), and a decrease in the functional dispersion of specific leaf area. …”

Electric Images Produced by Two Prey-Like Objects and Determination of <i>S_min</i> by David Babineau (379118)

“…All interobject distances are center-to-center, and object-to-fish lateral distances (i.e., perpendicular to fish midline) are from object center to skin surface.…”

Inflammatory activity and organ function/response under treatment with tocilizumab. by Sandra M. Ihne-Schubert (16814416)

“…<p>Graphical time series of markers of inflammatory activity (A) and conventional and innovative cardiac (B), renal (C) and hepatic organ function and response (D, E). The application time points of tocilizumab are shown as black diamonds. …”

Additional Analysis of visually induced calcium transients in Fig 6. by Maureen M. Sampson (9322886)

“…(<b>A</b>) The change in the secondary response (the magnitude of the calcium decrease following the initial peak). (<b>B</b>) Change in the exponential time constant k (units 1/sec) relative to epoch 1 (defined by ΔF/F(t) = c<i>e</i>^kt) for the time between 10% and 90% of the post-stimulus peak-to-peak difference in ΔF/F. …”

Schematic showing our postulated mechanism for maturation stage ameloblast sensitivity to fluoride. by Ramaswamy Sharma (247989)

“…F⁻ can reversibly associate with H⁺ ions to form HF. Approximately 25-fold more HF is formed at pH 6.0 as compared to pH 7.4. …”

Association of YFP::HTZ-1 Depends on <i>pha-4</i> Activity by Dustin L Updike (66077)

Identification of gene expression changes with inhibition of Notch signaling in rat AVICs. by Asha Acharya (195960)

“…In blue, direct transcriptional targets of Sox9; (*) genes with multiple hits. Decreased expression of cartilage-specific genes by qRT-PCR in AVICs with DAPT treatment (D) or when cultured in osteogenic media (OM) versus standard media (SM) (E). …”

Matrix deformation does not accompany stiffening as observed by confocal microcopy. by Maxwell A. Kotlarchyk (220210)

“…After rotation of the post by 2.4° there is a visible displacement in the gel in region R2 (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0020201#pone-0020201-g005" target="_blank">Fig. 5</a>), with little deformation in matrix geometry. (E) Comparison of fibrin pore volume shows significant pore volume reduction with increasing fibrin concentration, but not with rotation of the post in region R2 of the device, where AMR reports 10-fold stiffening (*p<0.05).…”

Comparison of the top 20 8-mers calculated using six different methods. by Ramkumar Hariharan (385641)

“…The top 20 8-mers ranked by decreasing fold enrichment scores from (a) our novel background model, the “Ak-1 method” were compared to those from the previously described C0/C1 method (b), from Markov models of order 4 sorted by Z-scores (c), from Markov models of order 4 sorted by Binomial probabilities (d), from Markov models of order 3 ranked by Z-scores (e) and, Markov models of order 3 ranked by binomial probabilities (f). …”

The Golgi two-hybrid assay detects interactions between a transcriptional activation domain and its binding partners. by Danielle H. Dube (234251)

“…<p><i>och1</i>Δ yeast were transformed with Gal4AD-CAT and LOC-Gal80 (A), LOC-Gal11 (B), LOC-Rpt4 (C), LOC-Hap5 (D), or LOC-Rpt6 (E). Yeast were grown on CSM-Leu-Ura plates in the presence of Congo red. …”

<i>cbf11</i> interacts genetically with <i>sty1</i> and <i>pka1</i> pathways. by Martin Převorovský (209870)

“…<b>(C)</b> Calcofluor staining documents that the occurrence of <i>Δcbf11</i>-associated septation defects (e.g., single cells with multiple septa) is decreased in the double mutants with <i>sty1</i> and <i>pka1</i>. …”

Image2_Retrospective analysis of the effect of SGLT-2 inhibitors on renal function in patients with type 2 diabetes in the real world.pdf by Rongjing Song (133760)

“…</p>Results<p>The eGFR levels significantly decreased to their lowest point (−3.04 mL/min/1.73 m²) in the first 3 months after initiation of SGLT-2 inhibitors treatment, however, gradually returned to the baseline level after 1 year. …”

Image1_Retrospective analysis of the effect of SGLT-2 inhibitors on renal function in patients with type 2 diabetes in the real world.pdf by Rongjing Song (133760)

“…</p>Results<p>The eGFR levels significantly decreased to their lowest point (−3.04 mL/min/1.73 m²) in the first 3 months after initiation of SGLT-2 inhibitors treatment, however, gradually returned to the baseline level after 1 year. …”

Table1_Retrospective analysis of the effect of SGLT-2 inhibitors on renal function in patients with type 2 diabetes in the real world.docx by Rongjing Song (133760)

“…</p>Results<p>The eGFR levels significantly decreased to their lowest point (−3.04 mL/min/1.73 m²) in the first 3 months after initiation of SGLT-2 inhibitors treatment, however, gradually returned to the baseline level after 1 year. …”