The upstream signaling to Nrf1 and proteasome are to no or fewer degrees, affected in <i>SREBP1</i>-deficient cells. by Keli Liu (5937368)

“…(D) The mRNA levels of those examined genes were determined by real-time qPCR and shown as fold changes (mean ± S.D. n = 3×3) with significant decreases (*, <i>p</i><0.01) or significant increases ($, <i>p</i><0.01) relative to equivalent controls. …”

Kinetics of alpaca innate immune responses at the tracheal level in response to MERS-CoV Qatar15/2015. by Nigeer Te (7849808)

“…TFs, transcription factors; CKs, chemokines; ADs, adaptors; RT, receptor. (B) Average fold changes of ISGs, PRRs, IL8, IL1β and IRF7 genes in trachea. …”

CD40 knockdown and CD40-luciferase assay in BL2 cells. by Gang Li (34549)

“…(E) Titration of IKK inhibitor VII leads to inhibition of luciferase activity following tCD40L activation. …”

Neural lamella remodeling is needed for macrophage invasion. by Bente Winkler (20760273)

“…(<b>C</b>) Panglial expression of <i>Pvf2</i> and concomitant knockdown of <i>STAT92E</i> decreases the number of invaded macrophages by ~ 10-fold. …”

Effects of GHS on sarcoplasmic reticulum (SR) Ca²⁺ content and phospho-phospholamban (p-PLB)/phospholamban (PLB) expression. by Yi Ma (167857)

“…(D) The time-to-90% decay of caffeine-induced increases in [Ca²⁺]_i mainly reflect the Ca²⁺ clearance ability of the Na⁺/Ca²⁺ exchanger (NCX). n  =  18, 44, 44, 33, 38, 41 and 38 cells/3 mice in G post control, control, ischemia, G pre, G post, H pre and H post, respectively. (E) Representative western blots of the total phospholamban (PLB) and the phosphorylated PLB (p-PLB) in 6 groups and (F) the densitometric quantification of ratio of p-PLB/PLB (expressed as fold increase relative to control). n  =  5 mice in each group. …”

Characterization of the Autophagy Marker Protein Atg8 Reveals Atypical Features of Autophagy in <i>Plasmodium falciparum</i> by Rahul Navale (452742)

“…Starvation, the best known autophagy inducer, decreased PfAtg8 level by almost 3-fold compared to the normally growing parasites. …”

Patterns of differential gene expression levels of candidate genes post infection in susceptible and resistant strains. by Nourtan F. Abdeltawab (89435)

“…<p>Quantitative PCR results showing levels of gene expression of 14 genes with significant (P = 0.05–0.08) change post-infection in susceptible and resistant strains, expressed as Log fold differences in gene expression level post-infection. …”

Time-Dependent Decay of mRNA and Ribosomal RNA during Platelet Aging and Its Correlation with Translation Activity by Catherine Angénieux (145933)

“…To attempt to solve this paradox, we studied changes in the RNA content of reticulated platelets, i.e., young cells brightly stained by thiazole orange (TO^bright), a fluorescent probe for RNAs. …”

The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling by Kine Andenæs (5566217)

“…Although collagen amount and cross-linking were comparable in FMOD-KO and wild-type, overexpression of fibromodulin in cardiac fibroblasts <i>in vitro</i> decreased their migratory capacity and expression of fibrosis-associated molecules, i.e. the collagen-cross linking enzyme lysyl oxidase, transglutaminase 2 and periostin. …”

Effect of position influence and environmental changes in hybrid torque-position BMI. by Pratik Y. Chhatbar (276591)

“…<p>(<b>A</b>) Decreasing position influence (, see methods) from 200 (n = 32) to 100 (n = 46; 42) to 20 (n = 75) and (<b>B</b>) from 20 (n = 127; 92) to 0 (pure torque control; n = 116; 77) moved the FSV locations away from the movement start-point and towards the target (<i>P</i><0.05), indicating more ballistic movement profiles. …”

The tombusvirus p33 replication protein binds to the yeast Scs2p VAP protein in the ER. by Daniel Barajas (255452)

“…Yeast was grown under similar conditions and images were taken as in panel C. (E) Decreased TBSV repRNA accumulation in <i>scs2Δ</i> yeast. …”

An explanation of the pRF dynamics in terms of feedback signals from extrastriate cortex. by Koen V. Haak (321925)

“…Interestingly, this model also predicts that increasing the size of the mask (shifting the fringe to the right) results in a decrease of the pRF expansion. This is indeed what appears to happen when the mask size increases from 5.0° to 7.5° (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037686#pone-0037686-g004" target="_blank">Figure 4B</a> and corresponding text).…”

<b>Supporting data for ''The pathogenicity and pathogenic mechanism of SARS-CoV-2 Omicron''</b> by Bingjie Hu (10835565)

Changing expression of candidate modifier genes alters larval density in the <i>AKHRi</i> model. by Audrey Nicol (19500765)

“…A positive change (>0) represents decreased FC50 and is suggestive of increased fat storage in the modifier strain as compared to the genetically-matched control. …”

Figure 4 from Zinc-alpha-2-glycoprotein Secreted by Triple-Negative Breast Cancer Promotes Peritumoral Fibrosis by Surbhi Verma (454998)

Data acquired from testing the effect of PAR1 inhibitors on Plasmodium falciparum-induced loss of endothelial cell barrier function by Janet Storm (8266991)

“…</div><div><br></div><div>The files are as follows:</div><div><div><b>-Combined analysis data for fig 2_TEER_includes normalisation.csv</b></div><div><b>-Combined analysis data for fig5_TEER_includes normalisation.csv</b></div><div><b>-Combined analysis data for fig6_TEER_includes normalisation.csv</b></div><div><b>-Data for fig2A+B+C_TEER_EA cells+inhibitors+thrombin_3.csv</b></div><div><b>-Data for fig2C_TEER_EA cells+inhibitors+thrombin_1.csv</b></div><div><b>-Data for fig2C_TEER_EA cells+inhibitors+thrombin_2.csv</b></div><div><b>-Data for fig3_flow cytometry HBMEC.csv</b></div><div><b>-Data for fig4A_TEER_aPC+thrombin_all time points shown.csv</b></div><div><b>-Data for fig4B_TEER_RBC+IE+lysate_all time points shown.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_#04-2+#91-2.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_#91-1.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_E5555-1+#04-1.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_E5555-2.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_Vorapaxar-1.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_Vorapaxar-2.csv</b></div><div><b>-Data for fig6_TEER_lysate_Vorapaxar+E5555+#04+#91-1.csv</b></div><div><b>-Data for fig6_TEER_lysate_Vorapaxar+E5555+#04+#91-2.csv</b></div><div><b>-Data for fig6_TEER_lysate_Vorapaxar+E5555+#04+#91-3.csv</b></div></div><div><br></div><div>The related publication investigated the hypothesis that the Thrombin-PAR1 coagulation/inflammation axis plays a significant role in barrier loss in cerebral malaria (CM), and that adjunct treatments targeting this might alleviate mortality or post-CM neurological sequelae in CM. …”

Induced dicentrics are variably stable over time. by Kaitlin M. Stimpson (243903)

The schematic diagram of the effects of inhibitors on protease activation and cartilage degradation. by Yi He (408132)

“…In summary, the activation of pro-enzyme is a key point in cartilage degradation of T+O treated bovine cartilage, which is regulated in an integrated cascade process.…”

Effects of cyclic stretch on cell reorientation. by Masataka Morioka (341795)

“…Total cell number (frequency) was set as 100% and the frequency in each group was expressed relative to the total cell number. (<b>E</b> and <b>F</b>) The mean and standard deviation (SD) of the cell orientation at each time point. …”

Somatosensory Abnormalities for Painful and Innocuous Stimuli at the Back and at a Site Distinct from the Region of Pain in Chronic Back Pain Patients by Christian Puta (390154)

“…Additionally, CLBP patients showed decreased pain thresholds at both sites. Importantly, there was no interaction between the investigated site and group, i.e. thresholds were changed both at the affected body site and for the site distinct from the painful region (hand). …”