Peripheral blood (PB) indices are similar in <i>NHD13</i> and <i>NHD13/Rag1</i>KO mice. by Sheryl M. Gough (323307)

“…(E) Representative FACS analysis of PB from mice of each genotype, aged 8 months, stained with the indicated antibodies.…”

CCDC6 knock down alters proliferation rate and increases cell death <i>in vitro</i>. by Angeliki Thanasopoulou (332490)

“…(<b>E</b>) Apoptotic cell death was analyzed by Po-PRO and 7-ADD staining. …”

Perfusion recovery. by Yinghuan Cen (3170154)

“…In group HD, the perfusion ratio was significantly elevated to 1.47–1.53 immediately post-surgery and each time point within 28 days. In group HID, the perfusion ratio slightly elevated immediately post-surgery and peaked to 1.69 on day 3 but decreased gradually after that and the ratio dropped to 1.25 on day 28 post-surgery.…”

Jip3 scaffolds lysosomes to DLIC for retrograde transport. by Catherine M. Drerup (383296)

“…Pink and yellow arrowheads point to two retrograde Jip3/Lamp1 positive cargos. …”

Short-read polishing tool benchmarking results using six clusters of genomes with real ONT and Illumina reads. by Ryan R. Wick (4096429)

Granuloma scores. by Masahiro Ishizuka (795418)

“…<p>The granuloma scores were obtained by counting the numbers of granulomata individually at 100 × magnification. Each data point represented average number of granulomata from 10 microscopic fields from H&E stained lung section from one mouse. …”

FGF signalling regulates expression of <i>osx</i>. by Katharina Felber (839136)

“…<p>(A-H) Larvae were treated at 48hpf, fixed at 51hpf and expression of several bone markers was analysed by in situ hybridisation. Arrowheads point to the opercle in the high magnification images to the right of each panel. …”

PAK1 Expression in schizophrenia. by Anthony J. Deo (251830)

“…Points above the line indicate increased expression in schizophrenia subjects, points below the line indicate decreased expression in schizophrenia subjects. …”

Morphology of the chromatoid body in <i>Sam68^−/−</i> germ cells. by Valeria Messina (318557)

“…Abnormalities in the CB morphology were also commonly observed in <i>Sam68^−/−</i> late round spermatids, such as decreased amount of the chromatoid material (<b>E</b>) or excess space between the CB lobes (<b>F</b>). …”

Cathepsin K transgenic mice (black bars) and wild-type mice (white bars) were administered either saline or bleomycin for 1, 2, 3, and 4 weeks by Mrigank Srivastava (94935)

“…Total BAL fluid cell numbers (A), alveolar macrophages (B), exudate macrophages (C), neutrophils (D) and lymphocytes (E) were ascertained from Pappenheim-stained cytospin preparations of BAL fluid. …”

The onset, abundance and fitness of generalists. by Shenshen Wang (488302)

“…Above (marked by arrows) generalists are on average fitter than specialists; this requires a higher level of fitness conservation as ruggedness decreases (e.g. for <i>K</i> = 11 whereas for <i>K</i> = 3). …”

Detection of 1′′–3′ gcADPR in lysates of bacteria expressing the SARM1 TIR domain. by Jeremy Garb (18405156)

“…Bar graphs represent the average of three independent replicates, with individual data points overlaid. Asterisk marks statistically significant decrease (Student’s <i>t</i>-test, two-sided, <i>P</i> <0.05).…”

Endogenous Tf synthesis and secretion to culture media. by Lucas Silvestroff (175320)

“…<p>Tf immunodetection (green) was observed in discrete cells with heterogeneous morphologies during <i>proliferation</i> (A–C). During <i>differentiation</i>, Tf (D, green) was observed in some GFAP⁺ cells (E and F, red). …”

Image5_Effect of Rumex dentatus on Gastrointestinal Protection and Toxicology in Rodents via Investigating H+/K+-ATPase, Calcium Channels, and PDE Mediated Signaling.tiff by Neelam Gul Qazi (13178827)

“…Extracts and emodin also show an inhibitory effect against H⁺/K⁺-ATPase. Rumex dentatus showed a gastroprotective and antioxidant effect. Histopathological evaluation showed improvement in cellular architecture and decrease in the expression of inflammatory markers such as cyclooxygenase (COX2), tumor necrosis factor (TNF-α), and phosphorylated nuclear factor kappa B (p-NFƙB), validated through immunohistochemistry, ELISA, and western blot techniques. …”

Increased BMP/TGFB signaling pathway activity in <i>Rx > cre Myrf</i>^<i>fl/fl</i> mutants. by Michelle L. Brinkmeier (18709048)

“…(C-<i>Myrf</i>^<i>fl/fl</i>; M-<i>Rx > cre Myrf</i>^<i>fl/fl</i>) (B) VlnPlot representation of transcript levels of <i>Wfikkn2</i>, <i>Tgfb2,</i> and <i>Id3</i> in theRPE cluster highlighting a decrease in the pathway inhibitor, <i>Wfikkn2</i> and increases in <i>Tgfb2</i> and <i>Id3</i>. …”

Image1_Effect of Rumex dentatus on Gastrointestinal Protection and Toxicology in Rodents via Investigating H+/K+-ATPase, Calcium Channels, and PDE Mediated Signaling.tiff by Neelam Gul Qazi (13178827)

“…Extracts and emodin also show an inhibitory effect against H⁺/K⁺-ATPase. Rumex dentatus showed a gastroprotective and antioxidant effect. Histopathological evaluation showed improvement in cellular architecture and decrease in the expression of inflammatory markers such as cyclooxygenase (COX2), tumor necrosis factor (TNF-α), and phosphorylated nuclear factor kappa B (p-NFƙB), validated through immunohistochemistry, ELISA, and western blot techniques. …”

<i>Spidey</i> expression during development is essential for adult survival. by Yin Ning Chiang (1718815)

“…Survival % is calculated as the number of successfully eclosed adults relative to the total number of male and female embryos; E: embryo; L1: 1^st instar larvae; L2: 2^nd instar larvae; L3: 3^rd instar larvae; P: pupae. N = 50 embryos for each stage. See <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1006126#pgen.1006126.s012" target="_blank">S6 Table</a> for full genotypes. …”

Effect of Intramuscular Injection of pH, lactate, ATP, and α,β–meATP on Muscle Withdrawal Threshold. by Nicholas S. Gregory (796912)

“…<p>Muscle withdrawal threshold was measured before and 30 minutes after injection of physiologic and supraphysiologic concentrations of pH, lactate, ATP, and α,β–meATP. (A) pH dose response curve. Rats were injected with normal saline adjusted to neutral pH (n = 6), pH 4.0 (n = 12), pH 4.5 (n = 6), pH 5.0 (n = 6), and pH 6.0 (n = 6). …”

Table1_Effect of Rumex dentatus on Gastrointestinal Protection and Toxicology in Rodents via Investigating H+/K+-ATPase, Calcium Channels, and PDE Mediated Signaling.docx by Neelam Gul Qazi (13178827)

“…Extracts and emodin also show an inhibitory effect against H⁺/K⁺-ATPase. Rumex dentatus showed a gastroprotective and antioxidant effect. Histopathological evaluation showed improvement in cellular architecture and decrease in the expression of inflammatory markers such as cyclooxygenase (COX2), tumor necrosis factor (TNF-α), and phosphorylated nuclear factor kappa B (p-NFƙB), validated through immunohistochemistry, ELISA, and western blot techniques. …”

Table_1_Integrative Brain Transcriptome Analysis Reveals Region-Specific and Broad Molecular Changes in Shank3-Overexpressing Mice.XLSX by Chunmei Jin (5705060)

“…We also re-analyzed previously reported RNA-sequencing results of the striatum of adult Shank3 TG mice and of the prefrontal cortex of juvenile Shank3^+/^Δ^C mice with a 50–70% reduction of Shank3 proteins. We found that several myelin-related genes were significantly downregulated specifically in the mPFC, but not in the striatum or hippocampus, of adult Shank3 TG mice by comparing the differentially expressed genes (DEGs) of the analyses side by side. …”