Proteomic changes during vegetative development. by Jim P. Fouracre (11037647)

“…(A) GO terms enriched within the 50 proteins that have the strongest increasing or decreasing trend score. …”

Genotypic diversity measured by Shannon’s information entropy. by Olaf Witkowski (2633398)

“…<p>The information entropy measures the variety in the measure progressively decreases during the simulation, until it reaches a minimal value of 50 hartleys (information unit corresponding to a base 10 logarithm) around the millionth iteration, then restarts to increase slowly.…”

Upon depletion of corneal conventional dendritic cells, virus titers and the local corneal damages are significantly increased in primary herpes simplex keratitis. by Kai Hu (311882)

“…Keratitis severity was graded (n = 5/time point). <b>A:</b> Representative corneal photos of primary acute herpes simplex keratitis severity of the mice in different groups are shown. …”

Increase of soluble Sema4D and reorganization of Plexin-B1 receptor during vaginal development. by Takuji Ito (566032)

“…(B) The ratio of soluble Sema4D to total Sema4D increases significantly in 5-week-old mouse vaginal tissue. Each data point represents the mean ± SEM of 3 to 6 mice. *<i>P</i><0.05, ANOVA. …”

Effects of tesofensine and phentermine on locomotion, quiet-awake/sleep, and head weaving stereotypy in rats. by Claudia I. Perez (7824965)

“…Note that for phentermine, the onset of stereotypy decreases across days. E. For the first two days, the variables locomotion, quiet awake/sleep, onset, and stereotypy were analyzed using a clustering algorithm (t-SNE). …”

Thalidomide reduces glial activation. by Ping He (33281)

“…Counter staining was performed by haemotaxylin. Bars: 50 µm (<b>A, B</b>).</p>…”

DataSheet_1_Identifying hub genes in response to ustekinumab and the impact of ustekinumab treatment on fibrosis in Crohn’s disease.zip by Ying Xu (9172)

“…Introduction<p>Crohn’s disease (CD) is a chronic inflammatory disease. Approximately 50% of patients with CD progressed from inflammation to fibrosis. …”

Data_Sheet_1_The role of immune suppression in COVID-19 hospitalization: clinical and epidemiological trends over three years of SARS-CoV-2 epidemic.PDF by Marta Canuti (336637)

“…The proportion of immune suppressed patients among all hospitalizations (initially stable at <20%) started to increase around December 2021, and remained high (30–50%). This change coincided with an increase in the proportions of older patients and patients with co-morbidities and with a decrease in the proportion of patients with severe outcomes. …”

CDA deficiency leads to excess dCTP, inhibiting PARP-1 activity and leading to UFB formation. by Simon Gemble (168663)

“…(G) (1) CDA deficiency leads to intracellular dCTP accumulation, decreasing basal PARP-1 activity. (2) The decrease in basal PARP-1 activity leads to an increase in unreplicated DNA sequences (preferentially at centromeres and CFS sites). (3) During late G2/early mitosis, some of this unreplicated DNA is probably processed by MUS81-EME1 and ERCC1 nucleases as previously suggested [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005384#pgen.1005384.ref036" target="_blank">36</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005384#pgen.1005384.ref012" target="_blank">12</a>], leading to DNA synthesis during metaphase (EdU foci) and preventing supernumerary UFB formation. (4) Some of the excess unreplicated DNA sequences are not processed by the nucleases, leading to supernumerary UFB formation.…”

Table_1_Narrowing row spacing and adding inter-block promote the grain filling and flag leaf photosynthetic rate of wheat under enlarged drip tube spacing system.xlsx by Jianguo Jing (18767383)

“…The decline of NS22 (9.93%) was higher than that of NS44 (9.04%), and both cultivars also showed a greater decrease in grain weight and average grain-filling rate (AGFR) of inferior grains (NS22: 23.19%, 13.97%; NS44: 7.78%, 5.86%) than the superior grains (NS22: 10.60%, 8.33%; NS44: 4.89%, 4.62%). …”

DataSheet_1_Narrowing row spacing and adding inter-block promote the grain filling and flag leaf photosynthetic rate of wheat under enlarged drip tube spacing system.zip by Jianguo Jing (18767383)

“…The decline of NS22 (9.93%) was higher than that of NS44 (9.04%), and both cultivars also showed a greater decrease in grain weight and average grain-filling rate (AGFR) of inferior grains (NS22: 23.19%, 13.97%; NS44: 7.78%, 5.86%) than the superior grains (NS22: 10.60%, 8.33%; NS44: 4.89%, 4.62%). …”

Age-related effects of the COVID-19 pandemic on mental health of children and adolescents by Stefanie J. Schmidt (6259154)

“…Adolescents experienced a significantly larger decrease in emotional and behavioural problems than both preschoolers and school-children. …”

Image1_Total flavonoids extracted from Penthorum chinense Pursh mitigates CCl4-induced hepatic fibrosis in rats via inactivation of TLR4-MyD88-mediated NF-κB pathways and regulatio... by Sujuan Wang (1865149)

“…Subsequently, rats were randomly assigned to a control group (Control), a carbon tetrachloride (CCl₄)-induced hepatic fibrosis model group (Model), a positive control group [0.2 mg/(kg∙day)] of Colchicine), and three TFPCP treatment groups [50, 100, and 150 mg/(kg∙day)]. …”

Layer-specific quantification of RS and FS neuronal activity in wM2 across learning. by Vahid Esmaeili (12700352)

“…Left: baseline-subtracted (50 ms prior to whisker onset) population firing rate (mean ± SEM) for different cortical layers (L2/3, L5, and L6a) overlaid for Novice mice (244 neurons in 7 mice) and Expert mice (401 neurons in 11 mice). …”

Image2_Total flavonoids extracted from Penthorum chinense Pursh mitigates CCl4-induced hepatic fibrosis in rats via inactivation of TLR4-MyD88-mediated NF-κB pathways and regulatio... by Sujuan Wang (1865149)

“…Subsequently, rats were randomly assigned to a control group (Control), a carbon tetrachloride (CCl₄)-induced hepatic fibrosis model group (Model), a positive control group [0.2 mg/(kg∙day)] of Colchicine), and three TFPCP treatment groups [50, 100, and 150 mg/(kg∙day)]. …”

High-frequency DPOAE sources in children (Dreisbach et al., 2023) by Laura Dreisbach (16535774)

“…</p><p dir="ltr"><b>Method:</b> DPOAEs were collected with varied frequency ratios (<i>f</i>₂/<i>f</i>₁ = 1.1–1.25) for a wide range of frequencies (2–16 kHz) in 39 younger (3–6 years) and 41 older (10–12 years) children with constant levels (L₁/L₂) of 65/50 dB SPL. …”

Basal PLD activity is strongly stimulated by the D1/5R agonist and blocked by the D1/5R, mGluR5, mGluR1, and the PLD-linked mGluR antagonists in the amygdala of cocaine CPP animals... by Balaji Krishnan (203728)

“…The D1/5R antagonist, SCH23390, completely blocked basal PLD activity (91.2±21.9, n = 12, ^##<i>p</i><0.01) in the cocaine CPP group. A similar reduction in PEtOH levels was observed with application of either the PLD-linked mGluR antagonist, PCCG-13 (62.9±10.6, n = 7, ^##<i>p</i><0.01) or the mGluR1 antagonist, LY367385 (75.0±13.9, n = 12, ^##<i>p</i><0.01), while the mGluR5 antagonist, MPEP, did not decrease basal PLD activity (305.7±31.5, n = 7, ns) within the cocaine CPP group but were significantly increased compared to (*<i>p</i><0.05) the saline treated group. …”

Image_1_Archetypal type II and III Toxoplasma gondii oocysts induce different immune responses and clinical outcomes in experimentally infected piglets.tif by Andrea Largo-de la Torre (13985607)

“…Apathy and a moderate decrease in feed consumption were observed in G1 and G2 piglets between 5 and 8 dpi, coinciding with fever (>40°C). …”

Coronary artery disease is associated with an altered gut microbiome composition by Takumi Toya (690584)

Fluorescence Linked Enzyme Chemoproteomic Strategy for Discovery of a Potent and Selective DAPK1 and ZIPK Inhibitor by David A. Carlson (1867249)