Microsatellite Instability and Mistmatch Repair protein analysis by Salvador J. Diaz-Cano (100072)

“…<p>Microsatellite Instability Testing in CRC and Interpretation</p> <p>Microsatellite instability is a type of mutation that occurs in microsatellite regions (short polymorphic DNA segments) by nucleotide addition (increased size) or nucleotide loss (decreased size) in the repeats. …”

Salinity and nitrogen removal rate. by Valentin Faust (13176389)

Peg13 attenuates the sevoflurane-induced NSC damage. by Yunfeng Jiang (2589892)

“…Transduction with OE-Peg13 at MOI of 10 increased Peg13 transcripts by 1.8 folds, determined by qRT-PCR. G, H. Peg13 over-expression recovered the sevoflurane-decreased neurosphere formation in NSCs. …”

Reduced control model M4: Normative evidence accumulation. by Veith Weilnhammer (2909060)

“…History-congruent amounted to 50.73% ± 0.07% of trials (in blue). As in the full model, the no-oscillation model showed a significant bias toward perceptual history T(4.32×10³) = 9.94, <i>p</i> = 4.88×10⁻²³; upper panel). …”

WFS1 deficiency leads to impaired neuronal development. by Michal Cagalinec (3151077)

“…(D–F) WFS1 deficiency retards growth of the longest axon (D) and growth of the axonal tree (E) and decreases the number of axon tips (F). (G) Survival of WFS1-deficient neurons is decreased when compared with control neurons (<i>n</i> = 61–62 individual dishes from 17 independent sister cultures at DIV 6–11). …”

<i>Cobl</i> KO mice fail to show repair of the dendritic arborization defects caused by MCAO in both layer II/III and layer V neurons of the ipsilateral hemisphere. by Yuanyuan Ji (455424)

“…Note that dendritic branching points (<b>E</b>), dendritic terminal points (<b>F</b>), total dendritic tree length (<b>G</b>), and Sholl intersections (<b>H-J</b>) were all decreased at 24 hours after MCAO and that, in contrast to WT animals (<b><a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3001399#pbio.3001399.g005" target="_blank">Fig 5</a></b>), none of these phenotypical parameters recovered during the days after MCAO in <i>Cobl</i> KO mice. …”

Connecting Protein Conformation and Dynamics with Ligand–Receptor Binding Using Three-Color Förster Resonance Energy Transfer Tracking by Mark Kastantin (1514023)

“…By controlling FN structure and dynamics through tuning surface chemistry, we found that as the conformational and translational dynamics of FN increased, the rate of binding, particularly to folded FN, and stability of the bound FN−α_vβ₃ complex decreased significantly. …”

Connecting Protein Conformation and Dynamics with Ligand–Receptor Binding Using Three-Color Förster Resonance Energy Transfer Tracking by Mark Kastantin (1514023)

“…By controlling FN structure and dynamics through tuning surface chemistry, we found that as the conformational and translational dynamics of FN increased, the rate of binding, particularly to folded FN, and stability of the bound FN−α_vβ₃ complex decreased significantly. …”

Histopathological scores and histopathologies of EAU mice. by Kayo Suzuki (166737)

“…Furthermore, these scores were further decreased when treated by inhibiting both Ang2 and VEGFA (i.e., anti-Ang2 antibody with anti-VEGFA antibody treatment group and anti-Ang2/VEGFA bispecific antibody treatment group) (P<0.01). …”

Carbonyl Post-Translational Modification Associated with Early Onset Type 1 Diabetes Autoimmunity by Mei-Ling Yang (3625355)

Initial Mutations Direct Alternative Pathways of Protein Evolution by Merijn L. M. Salverda (228413)

“…We found that a combination of decreased enzymatic activity and lower folding cooperativity underlies negative sign epistasis in the clash between key mutations in the common and deviating lines (Gly238Ser and Arg164Ser, respectively). …”

Regular spiking neuron (sustained chopper) that exhibits accurate identification of envelope frequency from its spike trains. by Chris Scholes (3309477)

“…<b>e.</b> Period histograms, folded across stimulus periods, indicate reliable firing at certain phases of the stimulus cycle. …”

Rotavirus replication, maturity and cytopathic effect of cultured extrahepatic biliary epithelia (EHBE). by Jiexiong Feng (345975)

“…Significantly less double-layered particles (DLPs, pointed by black arrows) and triple-layered particles (TLPs, pointed by black arrow heads with dash lines) existed in siNSP4 protected EHBE. siVP7 caused more synthesis of DLPs. …”

Longitudinal intravital fluorescence and svOCT imaging of radioresponse in tumor and vascular compartments <i>in vivo</i>. by Azusa Maeda (141179)

SAP regulates the stability of KIX8 and KIX9. by Na Li (6550)

“…<p><b>(A-B)</b> The proteasome inhibitor MG132 stabilizes KIX8 (<b>A</b>) and KIX9 (<b>B</b>). …”

Disparities in COVID-19 primary vaccine series and boosters among Black, Hispanic, and Asian versus White residents of the same zip code. by Aaloke Mody (602279)

“…The dashed line represents equitable vaccine distribution between the racial/ethnic groups being compared. Points above the dashed line indicate that there was decreased vaccination in Black, Hispanic, or Asian residents compared to White residents (and vice versa). …”

A flow chart summarizing the results of this and other studies investigating the postnatal periods of lowest and greatest larynx sensitivity to androgen exposure and the mechanism... by Leila Grisa (293136)

“…At puberty, the larynx, vocal folds, and vocal tract (e.g., the resonance tube up to the oral cavity) acquire increased mass, leading to variable degrees of F0 reduction in men at adrenarche and gonadarche and to partial reduction in women at adrenarche. …”

Data_Sheet_1_Scent releasing silicone septa: A versatile method for bioassays with volatiles.ZIP by Franz K. Huber (13878059)

“…After removal of the septum from the solution and a drying period of 1 h to allow for evaporation of the solvent, the silicone emits the volatiles at a continuously decreasing rate for a minimum of 24 h. In this study, we measure the variability of the emission and quantify the emission of 22 common floral scent compounds at four different time points and in four different soaking concentrations. …”

PolyP levels stabilize the Ft-MglA and Ft-SspA interaction in a bacterial two-hybrid system. by Algevis P. Wrench (276279)

“…Assays were performed with cells of the <i>E. coli</i> reporter strains AW23 (Δ<i>sspA</i>), AW24 (Δ<i>sspA</i> Δ<i>relA</i> Δ<i>spoT</i>) and AW26 (Δ<i>sspA</i> Δ<i>ppKppX</i>) carrying the pBR-<i>mglA</i>-ω and pACTR-<i>sspA</i>-Zif. …”

Video_2_Automated in vivo Tracking of Cortical Oligodendrocytes.MP4 by Yu Kang T. Xu (8911391)