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19761
TGF-β1 increased Snail expression in cultured ARPE-19 cells.
Published 2013“…The increasing expression of mesenchymal markers fibronectin (B) and α-SMA (C) and the decreasing expression of epithelial markers E-cadherin (D) and ZO-1 (E). …”
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19762
Metformin does not further increase the median lifespan of DR-constitutive mutant eat-2, and metformin treatment triggers several DR phenotypes in wild-type <i>C. elegans</i> witho...
Published 2010“…<p><b>A.</b> Survival curves of <i>eat-2(ad1116)</i> mutants raised on 0 mM, 1 mM, 10 mM, and 50 mM metformin plates at 20°C. …”
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19763
Telomere length regulates Fst/BMP/pSmad signaling.
Published 2019“…<p>(A) Scatter plots showing global differential gene expression profile of WT and G4 <i>Terc</i><sup>–/–</sup>ES cells. …”
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19764
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19765
Variation of average codeword length (ACL) by number of edges.
Published 2020“…A positive variation indicates a decrease in the ACL. …”
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19766
B-Myb binds to and regulates Oct4 promoter activity.
Published 2013“…In undifferentiated cells, an amplification signal 10–15-fold above that seen in the IgG control is observed; however, this signal is reduced to only 2–4 fold above the IgG control following withdrawal of LIF and FCS. …”
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19767
FIGURE 1 from D-2-HG Inhibits <i>IDH1<sup>mut</sup></i> Glioma Growth via FTO Inhibition and Resultant m6A Hypermethylation
Published 2024“…Note that the total RADAR gene number is slightly larger here than the totals in <b>J</b>, because this list includes all <i>P</i> < 0.01 transcripts (including those with low magnitude fold changes). <b>L,</b> Supervised hierarchical clustering heat map of intersectional TCGA and RADAR data between U87, NHA, and gliomasphere cell lines that conformed to m6A and RNA expression conventions (i.e., an increase in RADAR m6A expression corresponded to a decrease in TCGA RNA expression). …”
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19768
The kava root extract and kavalactones down-regulate expression of AR and AR target genes (<i>PSA</i> and <i>TMPRSS2</i>) via accelerating the degradation of AR protein.
Published 2013“…The protein expression of AR and PSA in LNCaP and C4-2B cells after indicated treatments at a concentration of their IC<sub>50 s</sub> for 16 hours was analyzed by Western blot. α-Tubulin was detected as a loading control. …”
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19769
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19770
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19771
Scutellarin’s Cardiovascular Endothelium Protective Mechanism: Important Role of PKG-I<i>α</i>
Published 2015“…The activation of PKG–1α was then studied using targeted proteomic analysis (MRM-MS) checking the phosphorylation state of the autophosphorylation domain (aa42-94). Significant decrease in phosphorylation of PKG-Iα at Ser50, Ser72, Ser89 was induced by HR injury while SCU treatment significantly increased the phosphorylation of PKG-Iα, not only at Ser50, Ser72 and Ser89, but also at Ser44 and Thr58 (two novel phosphorylation domains). …”
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19772
Histone deacetylase (HDAC) inhibitor assessment.
Published 2016“…ITF 2357, an HDAC inhibitor which is structurally and functionally similar to SAHA, produced a dose-response curve with IC<sub>50</sub> of 0.2 μM. …”
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19773
Plk1 inhibition suppresses the clonogenic potential of SUM149 and SUM159.
Published 2019“…(B) EC<sub>50</sub> was defined as 50% colony inhibition. Single agents EC<sub>50</sub> were reported for each TNBC cell line and drug. …”
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19774
Image2_Peripheral blood T-cell modulation by omalizumab in chronic urticaria patients.jpeg
Published 2024“…</p>Results<p>In patients with CSU under treatment with omalizumab, there was a significant decrease in the percentage of naïve and an increase in the percentage of central memory CD4 T cells as well as a decrease in the percentage of naïve and increase in the percentage of effector CD8 T-cell subsets. …”
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19775
Image1_Peripheral blood T-cell modulation by omalizumab in chronic urticaria patients.jpeg
Published 2024“…</p>Results<p>In patients with CSU under treatment with omalizumab, there was a significant decrease in the percentage of naïve and an increase in the percentage of central memory CD4 T cells as well as a decrease in the percentage of naïve and increase in the percentage of effector CD8 T-cell subsets. …”
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19776
Table4_Peripheral blood T-cell modulation by omalizumab in chronic urticaria patients.docx
Published 2024“…</p>Results<p>In patients with CSU under treatment with omalizumab, there was a significant decrease in the percentage of naïve and an increase in the percentage of central memory CD4 T cells as well as a decrease in the percentage of naïve and increase in the percentage of effector CD8 T-cell subsets. …”
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19777
Image3_Peripheral blood T-cell modulation by omalizumab in chronic urticaria patients.pdf
Published 2024“…</p>Results<p>In patients with CSU under treatment with omalizumab, there was a significant decrease in the percentage of naïve and an increase in the percentage of central memory CD4 T cells as well as a decrease in the percentage of naïve and increase in the percentage of effector CD8 T-cell subsets. …”
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19778
Table3_Peripheral blood T-cell modulation by omalizumab in chronic urticaria patients.docx
Published 2024“…</p>Results<p>In patients with CSU under treatment with omalizumab, there was a significant decrease in the percentage of naïve and an increase in the percentage of central memory CD4 T cells as well as a decrease in the percentage of naïve and increase in the percentage of effector CD8 T-cell subsets. …”
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19779
Image4_Peripheral blood T-cell modulation by omalizumab in chronic urticaria patients.pdf
Published 2024“…</p>Results<p>In patients with CSU under treatment with omalizumab, there was a significant decrease in the percentage of naïve and an increase in the percentage of central memory CD4 T cells as well as a decrease in the percentage of naïve and increase in the percentage of effector CD8 T-cell subsets. …”
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19780
Table2_Peripheral blood T-cell modulation by omalizumab in chronic urticaria patients.docx
Published 2024“…</p>Results<p>In patients with CSU under treatment with omalizumab, there was a significant decrease in the percentage of naïve and an increase in the percentage of central memory CD4 T cells as well as a decrease in the percentage of naïve and increase in the percentage of effector CD8 T-cell subsets. …”