The impact of sample size reduction timing on the precision of the estimate of the differential effect of treatment. by Ognjen Arandjelović (295373)

New Targets for Drug Discovery against Malaria by Guido Santos (171018)

Novel Insights into Phosphorus Deprivation Boosted Lipid Synthesis in the Marine Alga <i>Nannochloropsis oceanica</i> without Compromising Biomass Production by Ying Shi (115282)

Effects of <i>tel1Δ rad3Δ</i> mutations on recruitment of telomere capping complexes. by Bettina A. Moser (260302)

“…Compared to untagged control, Poz1 showed significant telomere binding in wt, <i>tel1Δ</i>, <i>rad3Δ</i>, and <i>tel1Δ rad3Δ</i> (P values <0.0001), but no significant changes among wt and different mutant strains were found (P values ranged from 0.144 to 0.887). For Stn1 (E), mean values plus or minus one standard deviation from three to four independent experiments are plotted. …”

Influence of Fra on the heme maturation pathway. by Andreas Mielcarek (715578)

“…The deletion of <i>fra</i> led to a ~12-fold decrease of bsNos activity in the crude mutant cell extract (error bars represent SEM of three independent experiments). …”

NIK is responsible for noncanonical NF-κB activation in ovarian cancer cell lines. by Masaya Uno (522188)

“…Relative <i>NIK</i> mRNA levels are shown by fold increase in the mRNA abundance relative to the average of shCtl (arbitrarily set at 1). …”

Cilium disassembly defects were rescued with ectopic expression of CCDC66 but not CEP104. by Jovana Deretic (13113617)

“…Mean cilia length measured in 3D in CCDC66 depletion is decreased to 0.97-fold of the mean control length. …”

DataSheet1_PKPD Modeling of the Inoculum Effect of Acinetobacter baumannii on Polymyxin B in vivo.docx by Alexia Chauzy (12247643)

<i>P</i>. <i>aeruginosa</i> secreted virulence factors induce ER stress in primary bronchial epithelial cells. by Emily F. A. van ‘t Wout (756193)

“…Time-dependent induction of ER stress in primary bronchial epithelial cells, as assessed by <i>XBP1</i> splicing, <i>CHOP</i> and <i>GADD34</i> mRNA after treatment with CM-PAO1 (n = 5; mean ± SEM). B. Dose-response of spliced <i>XBP1</i>, <i>CHOP</i> and <i>GADD34</i> mRNA in primary bronchial epithelial cells treated with CM-PAO1 for 12 hours (n = 5; mean ± SEM). …”

Overexpression of miR-130a inhibits translation of mRNA containing the 3′UTR of FOG-2. by Gene H. Kim (371958)

“…Results reported are the mean±S.E.M. (n = 12); ‘*’ indicates statistically significant decrease in activity (p<0.001).…”

Effects of TTP2515 on metabolic and calorimetry parameters in leptin-deficient mice. by Roxanne Dutia (418714)

“…(<b>C</b>) Body weight was significantly lower in TTP2515-treated mice on the 50 mg/kg dose. (<b>D</b>) Immediately upon starting the 50 mg/kg dose, mean respiratory quotient was significantly decreased in TTP2515 treated mice during the light cycle. …”

Roles of Cochaperones HOP and CHIP in KCNQ4 Biosynthesis. by Yanhong Gao (244711)

“…Over-expression of cochaperone HOP led to a significant increase, whereas over-expression of CHIP resulted in a marked decrease in total KCNQ4 level. <i>E. & F. Effects of siRNA knockdown of HOP or CHIP on total KCNQ4 level</i> HEK293T cells were transfected with 0.4 µg of pCMV6-XL5-HA-KCNQ4 (+) and various amount of siRNA as indicated. …”

Time course development of insulin resistance, adipose and liver inflammation. by Petra Mulder (462809)

“…(B) HFD feeding resulted in a gradual decrease of tissue-specific uptake of glucose into white adipose tissue (WAT). …”

Effects of Skp2 loss of function on MG activation in retinal explants. by Carolina Beltrame Del Debbio (243080)

“…<p><b>(A)</b> Immunohistochemical analyses of lentivirus transduced retinal explants revealed a decrease in immunoreactivities corresponding to Skp2 in the Skp2 LOF group versus controls. …”

Constitutive CXCL12 stimulation induces a loss in adhesion through destabilization of focal adhesions. by Luke J. Drury (241337)

“…(D) Transwell co-cultures with HT29 cells expressing variable levels of CXCL12 resulted in a dose dependent decrease in adhesion. Values of top-well crystal violet staining shown are mean ± SD from three independent experiments completed in triplicate. * indicates statistically significant difference in panel D from GFP/GFP co-cultured cells (<i>P</i>≤0.05). …”

Figure S6 from Targeting AKT with Oridonin Inhibits Growth of Esophageal Squamous Cell Carcinoma <i>In Vitro</i> and Patient-Derived Xenografts <i>In Vivo</i> by Mengqiu Song (8858807)

“…Data are shown as mean values {plus minus} S.E. (B) Body weight of mice (EG9) was plotted over 40 days. …”

Table 2_Network meta-analysis of pharmacological treatment for antibody-mediated rejection after organ transplantation.docx by Junjie Sun (4383520)

“…A Bayesian NMA was conducted using R 4.4.0, RStudio software, and the GeMTC package to assess the outcomes in estimated glomerular filtration rate (eGFR), mean fluorescence intensity (MFI), g-score, and infection under pharmacological treatments.…”

Table 1_Network meta-analysis of pharmacological treatment for antibody-mediated rejection after organ transplantation.docx by Junjie Sun (4383520)

“…A Bayesian NMA was conducted using R 4.4.0, RStudio software, and the GeMTC package to assess the outcomes in estimated glomerular filtration rate (eGFR), mean fluorescence intensity (MFI), g-score, and infection under pharmacological treatments.…”

Effect of rutoside (RU) treatment on rat inflammatory mediators by Tina Kauss (46849)

“…Sera were collected at day 50 after immunization and tested for their concentrations in tumor necrosis factor-alpha (TNF-α), prostaglandin E(PGE), interleukin-1-beta (IL-1β), and monocyte chemoattractant protein-1 (MCP-1). …”

Individual neuron firing rates before and after injury. by Rachael Miller Neilan (10678614)

“…Data on the left and right are the same for the 60:40 and 50:50 models, but distinct for the 30:70 model (corresponding to lab data in <b><a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1009097#pcbi.1009097.g006" target="_blank">Fig 6</a></b>).…”