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Overexpression of <i>PF10_0355</i> decreases parasite susceptibility to halofantrine (HFN) and related antimalarials.
Published 2011“…Overexpression of <i>PF10_0355</i> decreases parasite susceptibility to (A) HFN and structurally related (B) mefloquine (MFQ) and (C) lumefantrine (LUM). …”
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Blockade of mTORC2 decreased TRPC6-dependent calcium influx in podocytes (confocal microscopy).
Published 2014“…Each trace represents the mean value that was derived from 3 cells or fields in a single experiment. …”
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Decreased miR-24 sensitizes cells to apoptotic stimuli, and increases pro-apoptotic protein expression.
Published 2013“…Infected cells were selected in puromycin and decreased expression of miR-24 validated by quantitative RT-PCR (<b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0055406#pone.0055406.s004" target="_blank">Fig S4</a></b>). …”