Effects of morpholino knockdown of zAE1b on neuromast hair cell. by Yuan-Hsiang Lin (2217232)

“…B and D: merged images of zAE1b and Par protein signals. (E) The Ca²⁺ influx of neuromast hair cells in zAE1b morpholino knockdown larvae was significantly decreased. …”

YC-1 Reverses Retinal Reactive Gliosis and Retinal Neovascularization, <i>in vivo</i> and <i>in vitro</i>. by Michael DeNiro (297385)

“…YC-1 treated animals exhibited a significant and a dose-dependent decrease in neovascular sprouts lengths as compared to DMSO-treated retinas. …”

Scrapie-infected brain homogenate causes PrP^C-dependent loss of dendritic spines. by Cheng Fang (611972)

“…The boxed regions in panels A, D, G, and H are shown at higher magnification in panels B, E, I, and J, respectively. Arrows in panels B, I, and J point to dendritic spines, and arrowheads in panel E indicate the positions of spines that have retracted. …”

Downstream molecular effects of knockdown of the expression of 5-HT_1B and 5-HT_1D receptors, on invasion and proliferation biomarkers in PaCa cells. by Nilgun Gurbuz (623605)

“…(Upper panel) Cells were transfected with 50 nM of indicated siRNAs, and after 72 h, the total RNA was extracted and the transcript levels of 5-HT_1B and 5-HT_1D were determined by standard RT-PCR as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0105245#s2" target="_blank">Materials and Methods</a>. …”

Profiling overall protein <i>O</i>-glycosylation pathway genes in <i>F. graminearum.</i> by Heeji Moon (17474719)

“…Sexual developments were categorized as discrete phenotypic traits and scored on a 4-point scale (a: no difference compared with wild-type, b: decreased number of perithecia and ascospore or delayed perithecia maturation or decreased number of discharged ascospores, c: no perithecia and ascospore formation or no ascospore discharge, e: essential genes). …”

Profiling overall protein <i>N</i>-glycosylation pathway genes in <i>F. graminearum.</i> by Heeji Moon (17474719)

“…Sexual developments were categorized as discrete phenotypic traits and scored on a 4-point scale (a: no difference compared with wild-type, b: decreased number of perithecia and ascospore or delayed perithecia maturation or decreased number of discharged ascospores, c: no perithecia and ascospore formation or no ascospore discharge, e: essential genes). …”

Table 1_Causality of circulating vitamins on infectious diseases: integrating Mendelian randomization and in vivo evidence.docx by Aling Tang (17523700)

VEGFR1 and VEGFR2 Involvement in Extracellular Galectin-1- and Galectin-3-Induced Angiogenesis by Nicky D'Haene (422477)

Genome-Wide Negative Feedback Drives Transgenerational DNA Methylation Dynamics in Arabidopsis by Tasuku Ito (728549)

Dendritic spine density is reduced exclusively at dystrophic, soluble Aβ and hyperphosphorylated tau accumulating dendrites. by Tobias Bittner (237241)

“…Note that the dendritic spine density of dystrophic dendrites significantly decreased over time, while the mean dendritic volume of the same dendrites significantly increased (*** P<0.001, repeated measures ANOVA, n = 4 mice per group). …”

Testing of the unknome set of genes for roles in fertility and wing growth. by João J. Rocha (16799016)

“…Hippo and Chico are controls as in (D), with CG11103 and CG5885 showing an increase or decrease in the posterior domain, respectively. The means and variances used for the graphs shown in the figure can be found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002222#pbio.3002222.s009" target="_blank">S2 Data</a> with the data points in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002222#pbio.3002222.s010" target="_blank">S3 Data</a>. …”

The morphogenesis and development of VM dopaminergic neurons is disturbed in <i>Dkk1^{<b>−/−</b>}</i> embryos. by Diogo Ribeiro (230483)

“…(B) Immunohistochemistry for TH in midbrain sections of <i>Dkk1^−/−</i> embryos revealed a decrease of aberrantly distributed dopaminergic neurons (upper panels) or an almost absence of dopaminergic neurons (bottom panels). …”

Emodin suppresses HG-induced cFLIP generation but not repressing its activation and increasing degration. by Junjie Gao (545578)

“…<p>(<b>a, b</b>) MCs were cultured in HG media and treated with 50 μM emodin for indicated times. …”

Shizukaol D inhibited the growth of liver cancer cells. by Lisha Tang (2580367)

“…(E) The transparent version of Focus cells treated with 0.00, 12.50, 25.00 and 50.00 μmol/L of shizukaol D for 48 hours. …”

The calcitron model and calcium-based plasticity rules. by Toviah Moldwin (10866708)

“…<b>(H)</b> Fixed points (black) and learning rates (pink) in the asymptotic fixed point – learning rate (FPLR) version of the calcium control hypothesis. …”

Autophagy activity affects Aβ_1–42 neurotoxicity. by Daijun Ling (188975)

“…<p>(A) <i>Drosophila</i> incorporating a heterozygous loss-of-function allele <i>Atg1^Δ3D</i> (<i>Atg1^+/−</i>) exhibit a significant decrease in expression levels of <i>Atg1</i> mRNA in fly brains (data are normalized mean+SEM relative to <i>GAPDH</i>, two-tailed P values by Student's t-test, n = 3 for each group). …”

Inhibition of inflammation in the brain of P. berghei-infected mice with ECM after treatment. by Nana O. Wilson (399957)

“…The leukocytes counts are mean ± standard error. A p value of <0.05 was considered significant. …”

Two-wave induction of the phosphate starvation response. by Yonat Gurvich (4683127)

“…To control for density-dependent effects, the growth rate was normalized by that of cells transferred to rich phosphate medium (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.2002039#sec010" target="_blank">Materials and methods</a>). The data in (E–F) are the mean and standard error of 2 replicates. …”

Transcriptional profile of indirect pathway markers. by Elizabeth K. Lucas (311415)

I-R-Polar-Negative-0902 by Sheng-Yuan Ho (16909464)

“…The first function gathered data with a low impact energy of 4 eV for the collision cell trap and 2 eV for the collision cell transfer, while the second function gathered data with a modulated transfer collision energy of 15 to 25 eV. …”