CARDIOVASCULAR RESPONSES AFTER ISOMETRIC HANDGRIP EXERCISE AT DIFFERENT INTENSITIES IN HEALTHY MEN by Igor Marcelino da Silva (6674021)

“…None of the experimental sessions promoted statistically significant changes in systolic and diastolic BP (p> 0.05 for all). After S50, there was a smaller increase in SDNN five minutes after the exercise (S50: +5±6, S30: +20±5, SC: +10±2 ms, p <0.05) and higher LF/HF after 20 minutes (S50: +1.59±0.80, S30: -0.49±0.49, SC: +0.39±0.49, p <0.05) compared to the other sessions. …”

Endomembrane asymmetry can be reoriented by Rhett Hadley (15215)

“…Bar = 50 m. (b) Adhesive deposition reversed following light reversal. …”

Structured illumination microscopy can resolve different synaptic domains. by Patricia T. Yam (478888)

“…Unpaired t-test, 6 fields of view. Graphs represent the mean ± s.e.m. (<b>F</b>,<b>G</b>) During depolarization of neurons with 50 mM KCl, the synaptic vesicle markers vGlut1 and synaptophysin become smaller and more numerous, and spread over larger area (brackets). …”

S4 Dataset - by Shinichi Chisada (15354141)

“…Our results revealed that the medaka <i>rad50</i> mutation concurrently reproduced tumorigenesis (8 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka), had a decrease in median survival time (65.7 ± 1.1 weeks in control vs. 54.2 ± 2.6 weeks in <i>rad50</i>^<i>Δ2/+</i> medaka, <i>p</i> = 0.001, Welch’s <i>t</i>-test), exhibited semi-lethality in <i>rad50</i>^{<i>Δ2/Δ2</i>} medaka and most of the major ataxia-telangiectasia phenotypes, including ataxia (rheotaxis ability was lower in <i>rad50</i>^<i>Δ2/+</i> medaka than in the control, Mann–Whitney U test, <i>p</i> < 0.05), and telangiectasia (6 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka). …”

S1 Dataset - by Shinichi Chisada (15354141)

“…Our results revealed that the medaka <i>rad50</i> mutation concurrently reproduced tumorigenesis (8 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka), had a decrease in median survival time (65.7 ± 1.1 weeks in control vs. 54.2 ± 2.6 weeks in <i>rad50</i>^<i>Δ2/+</i> medaka, <i>p</i> = 0.001, Welch’s <i>t</i>-test), exhibited semi-lethality in <i>rad50</i>^{<i>Δ2/Δ2</i>} medaka and most of the major ataxia-telangiectasia phenotypes, including ataxia (rheotaxis ability was lower in <i>rad50</i>^<i>Δ2/+</i> medaka than in the control, Mann–Whitney U test, <i>p</i> < 0.05), and telangiectasia (6 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka). …”

S3 Dataset - by Shinichi Chisada (15354141)

“…Our results revealed that the medaka <i>rad50</i> mutation concurrently reproduced tumorigenesis (8 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka), had a decrease in median survival time (65.7 ± 1.1 weeks in control vs. 54.2 ± 2.6 weeks in <i>rad50</i>^<i>Δ2/+</i> medaka, <i>p</i> = 0.001, Welch’s <i>t</i>-test), exhibited semi-lethality in <i>rad50</i>^{<i>Δ2/Δ2</i>} medaka and most of the major ataxia-telangiectasia phenotypes, including ataxia (rheotaxis ability was lower in <i>rad50</i>^<i>Δ2/+</i> medaka than in the control, Mann–Whitney U test, <i>p</i> < 0.05), and telangiectasia (6 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka). …”

S2 Dataset - by Shinichi Chisada (15354141)

“…Our results revealed that the medaka <i>rad50</i> mutation concurrently reproduced tumorigenesis (8 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka), had a decrease in median survival time (65.7 ± 1.1 weeks in control vs. 54.2 ± 2.6 weeks in <i>rad50</i>^<i>Δ2/+</i> medaka, <i>p</i> = 0.001, Welch’s <i>t</i>-test), exhibited semi-lethality in <i>rad50</i>^{<i>Δ2/Δ2</i>} medaka and most of the major ataxia-telangiectasia phenotypes, including ataxia (rheotaxis ability was lower in <i>rad50</i>^<i>Δ2/+</i> medaka than in the control, Mann–Whitney U test, <i>p</i> < 0.05), and telangiectasia (6 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka). …”

S5 Dataset - by Shinichi Chisada (15354141)

“…Our results revealed that the medaka <i>rad50</i> mutation concurrently reproduced tumorigenesis (8 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka), had a decrease in median survival time (65.7 ± 1.1 weeks in control vs. 54.2 ± 2.6 weeks in <i>rad50</i>^<i>Δ2/+</i> medaka, <i>p</i> = 0.001, Welch’s <i>t</i>-test), exhibited semi-lethality in <i>rad50</i>^{<i>Δ2/Δ2</i>} medaka and most of the major ataxia-telangiectasia phenotypes, including ataxia (rheotaxis ability was lower in <i>rad50</i>^<i>Δ2/+</i> medaka than in the control, Mann–Whitney U test, <i>p</i> < 0.05), and telangiectasia (6 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka). …”

Stable swimming of wildtype. by Shinichi Chisada (15354141)

“…Our results revealed that the medaka <i>rad50</i> mutation concurrently reproduced tumorigenesis (8 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka), had a decrease in median survival time (65.7 ± 1.1 weeks in control vs. 54.2 ± 2.6 weeks in <i>rad50</i>^<i>Δ2/+</i> medaka, <i>p</i> = 0.001, Welch’s <i>t</i>-test), exhibited semi-lethality in <i>rad50</i>^{<i>Δ2/Δ2</i>} medaka and most of the major ataxia-telangiectasia phenotypes, including ataxia (rheotaxis ability was lower in <i>rad50</i>^<i>Δ2/+</i> medaka than in the control, Mann–Whitney U test, <i>p</i> < 0.05), and telangiectasia (6 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka). …”

Unstable swimming of mutant. by Shinichi Chisada (15354141)

“…Our results revealed that the medaka <i>rad50</i> mutation concurrently reproduced tumorigenesis (8 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka), had a decrease in median survival time (65.7 ± 1.1 weeks in control vs. 54.2 ± 2.6 weeks in <i>rad50</i>^<i>Δ2/+</i> medaka, <i>p</i> = 0.001, Welch’s <i>t</i>-test), exhibited semi-lethality in <i>rad50</i>^{<i>Δ2/Δ2</i>} medaka and most of the major ataxia-telangiectasia phenotypes, including ataxia (rheotaxis ability was lower in <i>rad50</i>^<i>Δ2/+</i> medaka than in the control, Mann–Whitney U test, <i>p</i> < 0.05), and telangiectasia (6 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka). …”

Reducing Bmp4 signaling activity rescued atelectasis phenotype of <i>Fstl1^−/−</i> lung allografts. by Yan Geng (268097)

“…The graph represents the mean ± SEM of three independent experiments. (D) Dorsomorphin increased T1α staining but decreased pro SP-C staining in <i>Fstl1^−/−</i> lung allografts. …”

Upward and downward ramps in inferred spikes during reward approach in a virtual reality environment are detectable over a range of tuning parameters. by Weston Fleming (10924744)

“…For each tuning parameter, histograms of changes of inferred firing rate for each neuron, color coded by whether a neuron’s probability of firing significantly decreased (red), increased (blue), or did not change (grey) with increases in maze position. e. …”

Use of thermography to guide amputation levels. by Mario Aurelio Martínez-Jiménez (5963564)

“…<p>Thermographic imaging can be used as an adjunct to determine amputation levels in severely burned patients. A 24-year old patient with fourth degree burns in approximately 50% of his body surface area because of direct fire was admitted to the burn unit (A). …”

Non-monotonic induction of <i>icl1</i>. by Joao A. Ascensao (2273545)

“…While <i>sigE</i> copy number is increasing, <i>icl1</i> peaks at day 3 and decreases after that. …”

bpV(pic) reduces neuronal autophagosome aggregation. by Chandler L. Walker (188845)

“…Treatment with bpV promoted a decrease in neuronal autophagosome clustering. …”

Steroidogenic programme is differently regulated in the XX and XY gonads of <i>Wt1</i>^{<i>LoxP/GFP</i>}<i>;Wt1</i>^<i>Cre</i> mice. by Alejo Torres-Cano (12878169)

“…Values represent the mean ± s.e.m. (XY n = 4 and XX n = 3). *P < 0.05, Student’s <i>t</i>-test. …”

Effect of crizotinib and alectinib on stimulus preference of retinal ganglion cells. by Toshiyuki Ishii (53332)

“…<p>(A and B) Post-stimulus time histogram before (pre), during (crizotinib), and after (wash) the application of 1.0μM of crizotinib in an OFF-cell (A) and in an ON-OFF cell (B). …”

Example and group results. by Carsten Finke (351337)

“…Ellipse extent represents the horizontal and vertical standard deviation of saccade end points. Note decreased accuracy of the patients' saccade end points in the ALLO task. …”

Cerebellar neuronal response to yaw direction. by Tomaso Muzzu (5746691)

“…(D) Example unit decreasing its activity in both yaw directions. (E) Example unit that increases its activity in either yaw direction. …”

Effect of testosterone treatment on ligand-dependent activation of the EGFR and downstream signaling pathways in smooth muscle vascular cells. by Marta del Campo (596854)

“…The plots (B–E) present the mean ± SEM phosphorylation of the EGFR (n = 4) (B), p115 (n = 5) (C), Akt (n = 6) (D), and ERK1/2 (n = 6) (E) from a set of experiments similar to those shown in A.…”