Effects of 1 and 16 hr of AICAR incubation on p53 phosphorylation in keratinocytes, MEFs and other cells. by Yasuo Ido (172159)

“…<p><b>a.</b> Primary keratinocytes were incubated with 1 mM AICAR or 50 µM H₂O₂ (positive control) for 1 hr. …”

Clathrin-independent hERG internalisation. by Rucha Karnik (504688)

“…<p>(A) The distribution of HA-hERG_hERG or HA-K_ATP transiently expressed in HeLa cells was compared after 30 minutes incubation with anti-HA in the presence or absence of 80 µM dynasore, 5 mM MβCD, 5 mM αCD or 15 µM/50 µM SecinH3. …”

Effectiveness of botanical pesticide combined with <i>Beauveria bassiana</i> on mortality, nutritional index and fecundity of <i>Spodoptera litura</i> L. by Tasafima Tesari (18075622)

“…The activity of the mixture of pesticides at the LC₅₀ level has shown a synergistic effect. Thus, the mixture of botanical pesticides and <i>B. bassiana</i> could be developed as an alternative pesticide for sustainable biological control of <i>S. litura</i>.…”

Rapid chemical de-N-glycosylation and derivatization for liquid chromatography of immunoglobulin N-linked glycans by Akihiko Kameyama (2033902)

“…For N-linked glycan analysis, we investigated alkaline hydrolysis of the asparagine glycosyl carboxamide of glycoproteins as a deglycosylation reaction. By adding hydroxylamine into alkaline de-N-glycosylation, we suppressed the degradation of released glycans and obtained a mixture of oximes, free glycans, and glycosylamines. …”

Identification of cortactin as curcumin target in colon cancer cells. by Vijayababu M. Radhakrishnan (246310)

“…<p>(<b>A</b>) Table with 13 plasma membrane-associated proteins identified by QTOF-MS/MS as significantly decreased in T84 cell monolayers treated with curcumin. …”

Reduction of CSF leucocyte count and induction of apoptosis by roscovitine <i>in vivo.</i> by Uwe Koedel (263360)

“…<p>Wild type mice were subjected to pneumococcal meningitis by bacterial injection into the cisterna magna and treated either with a combination of ceftriaxone (100 mg/kg, intraperitoneally) and roscovitine (50 mg/kg intraperitoneally) or ceftriaxone and the vehicle of roscovitine (PBS+20% DMSO). …”

Communities of Arbuscular Mycorrhizal Fungi Detected in Forest Soil Are Spatially Heterogeneous but Do Not Vary throughout the Growing Season by John Davison (76123)

“…Different forest plots (each 10×10 m and separated from one another by 30 m) contained significantly different soil AMF communities, and the pairwise similarity of communities decreased with distance up to 50 m. However, there were no significant changes in community composition between different time points in the growing season (May-September). …”

Denervation induces an increase in excitatory synaptic strength. by Andreas Vlachos (47497)

“…<p>(<b>A</b>) Granule cell in a denervated culture at 3–4 days post lesion (dpl). …”

Baicalin reduces sunitinib-induced cardiotoxicity in renal carcinoma PDX model by inhibiting myocardial injury, apoptosis and fibrosis by Yuanqiao He (14518016)

“…Moreover, baicalin effectively protected SU-induced cardiac dysfunction by decreased the injury, apoptosis, and fibrosis. </p> <p>Conclusion: Collectively, our results demonstrate that baicalin as a potential cardioprotective approach for cardiovascular complications during sunitinib regimen. …”

Supplementary Material for: Reduced ING4 Expression Is Associated with the Malignancy of Human Bladder by Wang Y. (2884271)

“…<b><i>Results:</i></b> ING4 protein and mRNA were significantly decreased in bladder cancer tissues. ING4 protein level was significantly lower in the group of patients over 50 years of age. …”

Increased Uptake of CHF5633 by Alveolar Monocyte. by Atsuyasu Sato (315849)

“…SP-C in CHF5633 input sample was given a value of 1. SP-C relative to Sat PC was decreased in supernatant or smaller form surfactant to half of that in input sample and BALF pellet samples. …”

Morphofunctional evaluation of peripapillary retinoschisis associated with myopic posterior staphyloma and hyaloid traction: does it cause peripapillary vitreoretinal traction? by Fillipe B. Borges (13853248)

“…Multimodal retinal imaging showed peripapillary schisis in both the inner and outer retinal layers, grade II posterior vitreous detachment, and a tessellated fundus. Using Humphrey perimetry and MP-3 microperimetry, the functional evaluation indicated macular sensitivity within normal limits and decreased sensitivity in the peripapillary region, especially in right eye. …”

Increased functional avidity of memory CD4+ T cells from HIV controllers. by Benoît Vingert (252525)

“…The peptide dilution at half response (EC₅₀) and the last positive peptide dilution are indicated. …”

Supplementary Material for: Allopregnanolone and Pregnanolone Are Reduced in the Hippocampus of Epileptic Rats, but Only Allopregnanolone Correlates with Seizure Frequency by Lucchi C. (9255995)

“…<b><i>Results:</i></b> Decreased allopregnanolone (–50%; <i>p</i> < 0.05, Mann-Whitney test) and pregnanolone levels (–64%; <i>p</i> < 0.01) were found in the hippocampus, whereas pregnenolone sulfate, pregnenolone, progesterone, and 5α-dihydroprogesterone were nonsignificantly reduced. …”

Induction of by Guang-quan Li (299241)

“…Top, the ΔΨm in both dicycloplatin- and carboplatin-treated cells decreased in a concentration-dependent manner. Loss of ΔΨm was measured using JC-1 staining. …”

Effects of thermal process in bioactive compounds of mixed Brazilian cerrado fruit jam by Telma Melo BRANDÃO (10464403)

“…The results showed that there was a reduction in bioactive compounds in the jam of 44.37% for total phenolics, 50.56% for ascorbic acid, 78.40% total carotenoids, and 65.14% for antioxidant activity when compared with the mixed pulps. …”

The Impact of Phenotypic and Genetic Heterogeneity on Results of Genome Wide Association Studies of Complex Diseases by Mirko Manchia (423673)

“…For example, heterogeneity of 50% increases the required sample size by approximately three times. …”

<i>Yap (5SA)</i> mRNA-injected embryos exhibit dramatic downregulation of retinal photoreceptor genes. by Yoichi Asaoka (564124)

“…(B) A summary of microarray results for the top 50 downregulated genes in the <i>yap (5SA)</i>-expressing embryos in (A) compared with <i>yap (WT)</i>-expressing embryos at 42, 48 and 54 hpf. …”

Frequency of circulating Tfh subsets in patients with AS. by María-Belén Bautista-Caro (312513)

“…<p>A. AS/nb, but not AS/b patients, demonstrate an increased frequency of circulating CD4+CXCR5+CXCR3+CCR6- (Tfh-Th1) cells and a decreased frequency of CD4+CXCR5+CXCR3-CCR6+ (Tfh-Th17) cells as compared with HC, whereas the frequency of CD4+CXCR5+CXCR3-CCR6- (Tfh-Th2) cells is not different among the three groups. …”

The Increasing Importance of Gene-Based Analyses by Elizabeth T. Cirulli (242253)

“…Furthermore, I find that the genes reported in these papers are explaining a decreasing proportion of cases as the field moves past most of the low-hanging fruit, with 50% of the genes from studies in 2014 and 2015 having variants in fewer than 5% of cases. …”