Mossy fiber synaptic LTP - induced by place field specific spiking activity of dentate gyrus granule cells - is presynaptically expressed. by Anja Gundlfinger (366062)

“…(<b>D</b>) The mean rate of failures of synaptic transmission is decreased after expression of LTP. Upper traces show 50 individual sweeps (grey) and mean sweeps (black) in control and LTP condition of an exemplary whole-cell recording. …”

Low-Temperature Hypergolic Ignition of 1‑Octene with Low Ignition Delay Time by Haoqiang Sheng (9927645)

“…Compared with the ignition delay time of pure 1-octene (565 °C), the ignition delay time of 1-octene/BDMS (9:1.2) decreased by 3850% at 50 °C. Fourier transform infrared spectroscopy and gas chromatography–mass spectrometry confirmed the directional reaction of the hypergolic ignition reaction pathway of 1-octene and BDMS. …”

Low-Temperature Hypergolic Ignition of 1‑Octene with Low Ignition Delay Time by Haoqiang Sheng (9927645)

“…Compared with the ignition delay time of pure 1-octene (565 °C), the ignition delay time of 1-octene/BDMS (9:1.2) decreased by 3850% at 50 °C. Fourier transform infrared spectroscopy and gas chromatography–mass spectrometry confirmed the directional reaction of the hypergolic ignition reaction pathway of 1-octene and BDMS. …”

Tacrolimus and MPA can inhibit signaling pathway activation in whole-blood samples. by Nynke M. Kannegieter (3697594)

“…<p>(A) Phospho-p38MAPK (upper left panel), p-ERK (upper right panel) and p-Akt (lower panel) phosphorylation in monocytes was measured as MFI level. …”

Analysis of Genome-Wide Changes in the Translatome of Arabidopsis Seedlings Subjected to Heat Stress by Emilio Yángüez (447643)

“…For the majority of mRNAs, translation is severely repressed, causing a decreased of 50% in the association of the bulk of mRNAs to polysomes. …”

Vascular smooth muscle cells inhibit endothelial cell proliferation and drive Rac1-dependent morphogenesis. by Lasse Evensen (263932)

“…(C) Flow-cytometry analysis showed that HUVEC cells in co-culture have a 4.4-fold decreased proliferation activity compared to a HUVEC mono-culture. …”

The differences in homeostasis model assessment values in type 2 diabetic patients with different lengths of history of diabetes by Chen Wang (88408)

“…Conclusions There were obvious decreases in HOMA-β and increases in HOMA-IR in T2DM patients with a history of diabetes of less than 1 year compared with those in normal controls. …”

Targeted Next Generation Sequencing in Patients with Inborn Errors of Metabolism by Dèlia Yubero (3165915)

“…</p><p>Results</p><p>Genetic diagnosis was achieved in 50% of patients (73/146). In addition, the diagnostic yield obtained for Group 1 was 78% (63/81), and this rate decreased to 15.4% (10/65) in Group 2 (<i>X</i>² = 76.171; p < 0.0001).…”

Data_Sheet_1_Raman Spectroscopy Detects Changes in Carotenoids on the Surface of Watermelon Fruits During Maturation.docx by Tushar Dhanani (3351218)

“…<p>A non-invasive and non-destructive technique, Raman spectroscopy, was explored to distinguish different maturity stages (20, 30, 40, and 50 days after anthesis) of watermelon (Citrullus lanatus) fruits from four cultivars: Fascination, Orange Crisp, Amarillo and Crimson Sweet. …”

Trends in corneal transplantation from 2001 to 2016 in Brazil by Hirlana Gomes Almeida (5763455)

“…The analysis showed that there was a 2.4-fold increase in the number of corneal transplantations (from 6,193 [35.2 per million people (pmp)] to 14,641 [71 pmp]; p<0.001), a 50.7% increase in the efficacy of meeting the population’s demand for corneal transplantation (from 35.3% to 53.2%; p<0.001), an 11-fold increase in the number of corneal transplantation centers (from 32 to 356), and a 2.5-fold increase in the number of corneal transplantation teams (from 276 to 688) in Brazil during the period studied. …”

Trends in corneal transplantation from 2001 to 2016 in Brazil by Hirlana Gomes Almeida (5763455)

“…The analysis showed that there was a 2.4-fold increase in the number of corneal transplantations (from 6,193 [35.2 per million people (pmp)] to 14,641 [71 pmp]; p<0.001), a 50.7% increase in the efficacy of meeting the population’s demand for corneal transplantation (from 35.3% to 53.2%; p<0.001), an 11-fold increase in the number of corneal transplantation centers (from 32 to 356), and a 2.5-fold increase in the number of corneal transplantation teams (from 276 to 688) in Brazil during the period studied. …”

Perturbation of Mouse Retinal Vascular Morphogenesis by Anthrax Lethal Toxin by Jennifer L. Bromberg-White (259780)

“…Finally, co-injection of VEGF-neutralizing antibodies significantly decreased LeTx-induced neovascular growth. Our studies not only reveal that MAPK signaling plays a key role in retinal angiogenesis but also that perturbation of MAPK signaling by LeTx can profoundly alter vascular morphogenesis.…”

The strength of nucleosome positioning surrounding the TSS in <i>Drosophila</i> cell lines is correlated with gene expression level. by Rebecca L. Martin (4060348)

“…The expected pattern is observed where there is a strong +1 nucleosome upstream of the TSS followed by nucleosomes positioned with decreasing strength. …”

<i>Sox9</i> deletion during endocrine cell neogenesis results in reduced numbers of Pdx1⁺ cells. by Claire L. Dubois (346940)

“…Deletion of <i>Sox9</i> results in decreased expression of Pdx1 (<b>D, N</b>) as well as a reduction in the number of insulin⁺ (Ins⁺) cells, while Hnf6 (<b>F, P</b>), FoxA2 (<b>H, R</b>), and Tcf2 (<b>J, T</b>) expression is unaffected. …”

Distribution of ApoE-expressing microglia during phagocytosis shown by WISH. by Takako Yasuda (752735)

“…At 42 h after irradiation, the number of ApoE-expressing microglia had increased markedly (arrowheads in K and L) and they showed a branched morphology (M). The numbers of unstained areas in the TE and OT (open arrowheads in K and L) decreased and they were small, not hypertrophied. …”

Resveratrol Directly Binds to Mitochondrial Complex I and Increases Oxidative Stress in Brain Mitochondria of Aged Mice by Naïg Gueguen (93376)

“…<i>In vitro</i>, using solubilized complex I, we demonstrated a competition between NAD+ and resveratrol. At low doses (<5μM), resveratrol stimulated complex I activity, whereas at high dose (50 μM) it rather decreased it. …”

Repercussions of adjuvant-induced arthritis on body composition, soleus muscle, and heart muscle of rats by L.M. Pita (8527458)

“…Male rats were submitted to AIA induction by intradermal administration of 100 μL of Mycobacterium tuberculosis (50 mg/mL), in the right hind paw. Animals submitted to AIA were studied 4 (AIA4), 15 (AIA15), and 40 (AIA40) days after AIA induction as well as a control group of animals not submitted to AIA. …”

Triple stain for miR-200b, AE1/AE3, and laminin-5γ2 at the invasive front. by Kirsten Nguyen Knudsen (813125)

“…Scale bars 50 μm (A, C, D, E, F, G), and 25 μm (B, H).</p>…”

QC, including cluster size thresholding and declumping, improves precision, sometimes at the expense of recall, for images with lower SNR values. by Jenny M. Vo-Phamhi (11250803)

“…<b>(C)</b> Thresholding clusters by the number of annotations in the cluster and by the fraction of unique workers who contribute multiple times to the cluster improved recall by 17%, while decreasing precision by 11% on average, in an experiment with nine images with 50, 100, and 150 spots; mean SNR = 5, 10, and 15; and average nearest neighbor distance (NND) ≈ 11.5, 15, and 20.5.…”

Means and Standard Deviations of the MR imaging analyses and polysomnographic parameter. by Thomas Duning (220281)

“…</p><p>Patients with CSA-CSR showed significantly decreased sleep efficiency, a higher AHI and cAHI, and a more severe oxygen desaturation compared to patients without CSA-CSR. …”