DataSheet5_Lethal activity of BRD4 PROTAC degrader QCA570 against bladder cancer cells.ZIP by Qiang Wang (32383)

“…QCA570 potently induces degradation of BRD4 protein at nanomolar concentrations, with a DC₅₀ of ∼ 1 nM. It decreases EZH2 and c-MYC levels by transcriptional suppression and protein degradation. …”

DataSheet4_Lethal activity of BRD4 PROTAC degrader QCA570 against bladder cancer cells.ZIP by Qiang Wang (32383)

“…QCA570 potently induces degradation of BRD4 protein at nanomolar concentrations, with a DC₅₀ of ∼ 1 nM. It decreases EZH2 and c-MYC levels by transcriptional suppression and protein degradation. …”

DataSheet9_Lethal activity of BRD4 PROTAC degrader QCA570 against bladder cancer cells.ZIP by Qiang Wang (32383)

“…QCA570 potently induces degradation of BRD4 protein at nanomolar concentrations, with a DC₅₀ of ∼ 1 nM. It decreases EZH2 and c-MYC levels by transcriptional suppression and protein degradation. …”

DataSheet8_Lethal activity of BRD4 PROTAC degrader QCA570 against bladder cancer cells.ZIP by Qiang Wang (32383)

“…QCA570 potently induces degradation of BRD4 protein at nanomolar concentrations, with a DC₅₀ of ∼ 1 nM. It decreases EZH2 and c-MYC levels by transcriptional suppression and protein degradation. …”

DataSheet2_Lethal activity of BRD4 PROTAC degrader QCA570 against bladder cancer cells.ZIP by Qiang Wang (32383)

“…QCA570 potently induces degradation of BRD4 protein at nanomolar concentrations, with a DC₅₀ of ∼ 1 nM. It decreases EZH2 and c-MYC levels by transcriptional suppression and protein degradation. …”

DataSheet11_Lethal activity of BRD4 PROTAC degrader QCA570 against bladder cancer cells.ZIP by Qiang Wang (32383)

“…QCA570 potently induces degradation of BRD4 protein at nanomolar concentrations, with a DC₅₀ of ∼ 1 nM. It decreases EZH2 and c-MYC levels by transcriptional suppression and protein degradation. …”

DataSheet3_Lethal activity of BRD4 PROTAC degrader QCA570 against bladder cancer cells.ZIP by Qiang Wang (32383)

“…QCA570 potently induces degradation of BRD4 protein at nanomolar concentrations, with a DC₅₀ of ∼ 1 nM. It decreases EZH2 and c-MYC levels by transcriptional suppression and protein degradation. …”

Reduction of IL-17 after co-administration of donor-derived MSCs and Treg cells. by Eun-Sol Lee (737390)

“…(C) RORγ-t mRNA levels were significantly decreased in the combined cell therapy group versus the Treg cells single group using real-time PCR. …”

Direct Unequal Cleavages: Embryo Developmental Competence, Genetic Constitution and Clinical Outcome by Qiansheng Zhan (3374120)

Lamellipodial shape and protein and velocity distributions. by Ben Fogelson (510282)

“…Velocity at the boundary is normal to the boundary, and decreases in magnitude from a maximum when the normal points in the direction of cell motion to zero when the boundary is tangent to the direction of motion. …”

Table_1_Antimicrobial Resistance Pilot Surveillance of Pigs and Chickens in Vietnam, 2017–2019.XLSX by C. V. Tuat (11098677)

“…We conducted a pilot surveillance programme in five provinces of Vietnam, two in the south and three in the north, to identify antimicrobial resistance (AMR) in rectal swab samples from pigs and fecal samples from chickens at slaughter points during three different points in time from 2017 to 2019. …”

Image4_Formononetin isolated from Sophorae flavescentis inhibits B cell-IgE production by regulating ER-stress transcription factor XBP-1.tif by Nan Yang (305078)

“…Formononetin significantly and dose dependently decreased the IgE production in U266 cells across a concentration range of 2–20 µg/ml (p < 0.05–0.001 vs. untreated cells) with an IC50 value of 3.43 μg/ml. …”

Image5_Formononetin isolated from Sophorae flavescentis inhibits B cell-IgE production by regulating ER-stress transcription factor XBP-1.tif by Nan Yang (305078)

“…Formononetin significantly and dose dependently decreased the IgE production in U266 cells across a concentration range of 2–20 µg/ml (p < 0.05–0.001 vs. untreated cells) with an IC50 value of 3.43 μg/ml. …”

Image1_Formononetin isolated from Sophorae flavescentis inhibits B cell-IgE production by regulating ER-stress transcription factor XBP-1.tif by Nan Yang (305078)

“…Formononetin significantly and dose dependently decreased the IgE production in U266 cells across a concentration range of 2–20 µg/ml (p < 0.05–0.001 vs. untreated cells) with an IC50 value of 3.43 μg/ml. …”

Image2_Formononetin isolated from Sophorae flavescentis inhibits B cell-IgE production by regulating ER-stress transcription factor XBP-1.tif by Nan Yang (305078)

“…Formononetin significantly and dose dependently decreased the IgE production in U266 cells across a concentration range of 2–20 µg/ml (p < 0.05–0.001 vs. untreated cells) with an IC50 value of 3.43 μg/ml. …”

Image3_Formononetin isolated from Sophorae flavescentis inhibits B cell-IgE production by regulating ER-stress transcription factor XBP-1.tif by Nan Yang (305078)

“…Formononetin significantly and dose dependently decreased the IgE production in U266 cells across a concentration range of 2–20 µg/ml (p < 0.05–0.001 vs. untreated cells) with an IC50 value of 3.43 μg/ml. …”

Serum brain-derived neurotrophic factor reflects the lower inflammation, lipid level, and major adverse cardiac and cerebrovascular events risk in maintenance hemodialysis patients by Hui Du (639270)

“…BDNF negatively correlated with diabetes history, hemodialysis duration, C-reactive protein, total cholesterol, and low-density lipoprotein cholesterol in MHD patients. During a median follow-up period of 17.4 months, accumulating MACCE rate was calculated, which disclosed that high BDNF was correlated with decreased accumulating MACCE rate in MHD patients. …”

Primary and secondary screenings identify several molecules affecting the synchrony index of MIN6 cells. by Sabine Bavamian (148288)

“…<p>(<i>A</i>) The primary screening of 1040 compounds revealed that several molecules increased or decreased the synchrony index. …”

Deoxygenation of pyrolysis vapour derived from durian shell using catalysts prepared from industrial wastes rich in Ca, Fe, Si and Al by Tan, Y.L.

“…Catalytic fast pyrolysis of durian shell using waste-derived catalysts is an effective waste management strategy as the bio-oil produced can be a potential alternative source of energy or chemical feedstocks.…”
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DataSheet_1_Metabolomic and transcriptomic exploration of the uric acid-reducing flavonoids biosynthetic pathways in the fruit of Actinidia arguta Sieb. Zucc..docx by Yubo Wang (556762)

“…Zucc., a major cultivar in northern China, provides valuable information for the development of food and drug homologous functional foods.…”