Pentoxifylline, dexamethasone and azithromycin demonstrate distinct age-dependent and synergistic inhibition of TLR- and inflammasome-mediated cytokine production in human newborn... by Esther M. Speer (5158913)

“…<div><p>Introduction</p><p>Neonatal inflammation, mediated in part through Toll-like receptor (TLR) and inflammasome signaling, contributes to adverse outcomes including organ injury. Pentoxifylline (PTX), a phosphodiesterase inhibitor which potently suppresses cytokine production in newborn cord blood, is a candidate neonatal anti-inflammatory agent. …”

ED-1 stain of kidney tissue. by Rakesh K. Bijarnia (732576)

“…<p>The groups are (A) control, (B) EG-exposed, (C) EG+STS-exposed, (D) EG+SC-exposed, (E) EG+SS-exposed animal groups. The ED-1 stain was markedly increased in EG-exposed animals but decreased in all treatment groups. …”

Percentage of subjects with significant improvements following surgery. by Frances Hutchings (835365)

Data Sheet 1_Characteristics of cardiopulmonary exercise capacity in adults with different degrees of obesity.pdf by Shukun Deng (20583833)

Knockdown of CrzR in fat body/salivary glands results affects body mass from Systemic corazonin signalling modulates stress responses and metabolism in <i>Drosophila</i> by Olga I. Kubrak (659970)

“…Data are presented as means ± S.E.M, n = 4 replicates with 10-15 flies in every replicate…”

Data Sheet 1_The green tea component (−)-epigallocatechin-3-gallate protects against cytokine-induced epithelial barrier damage in intestinal epithelial cells.pdf by Rita Rosenthal (285303)

“…Among other beneficial effects, EGCG was shown to be protective in inflammatory bowel disease (IBD), a condition associated with barrier dysfunction. …”

Image 3_The green tea component (−)-epigallocatechin-3-gallate protects against cytokine-induced epithelial barrier damage in intestinal epithelial cells.tif by Rita Rosenthal (285303)

“…Among other beneficial effects, EGCG was shown to be protective in inflammatory bowel disease (IBD), a condition associated with barrier dysfunction. …”

Table_2_High Prevalence of Metallo-β-Lactamase-Producing Enterobacter cloacae From Three Tertiary Hospitals in China.xlsx by Yimei Cai (52714)

“…Notably, we identified the first NDM-1 and IMP-1 co-producing E. cloacae, carrying plasmids of several incompatibility (Inc) groups, including IncHI2, IncHI2A, and IncN. Most isolates showed decreased expression of ompC and/or ompF, and contained a broad distribution of ESBLs and AmpC β-lactamases. …”

Table_1_Physiological and Biomechanical Responses to Cross-Country Skiing in Varying Terrain: Low- vs. High-Intensity.docx by Trine M. Seeberg (5979200)

“…The terrain-dependent fluctuations did not differ between LI and HI for V.O2 (p = 0.50), whereas HR fluctuated less (p < 0.01) and displayed a time-dependent increase from Lap 2 to Lap 7 (7.8%-points, p > 0.01) during HI. …”

Mst1^−/− mice exhibit blunted MOG-specific proliferative and effector cytokine recall responses in vivo. by Konstantin V. Salojin (567844)

“…(<b>D</b>) Mice treated with an Mst1 inhibitor exhibit decreased severity of EAE. EAE was induced in C57Bl/6-Albino/129SvEv mice (n = 10 per treatment group) by immunization with MOGp35–55 in CFA and treated twice daily with the indicated doses of the Mst1 inhibitor LP-945706 administered by oral gavage in citrate buffed (pH 4.5, 0.1 M) 1% Tween 80 vehicle, starting one day after the onset of disease in 50% of the animals. …”

Table_2_Physiological and Biomechanical Responses to Cross-Country Skiing in Varying Terrain: Low- vs. High-Intensity.docx by Trine M. Seeberg (5979200)

“…The terrain-dependent fluctuations did not differ between LI and HI for V.O2 (p = 0.50), whereas HR fluctuated less (p < 0.01) and displayed a time-dependent increase from Lap 2 to Lap 7 (7.8%-points, p > 0.01) during HI. …”

Table_1_High Prevalence of Metallo-β-Lactamase-Producing Enterobacter cloacae From Three Tertiary Hospitals in China.xlsx by Yimei Cai (52714)

“…Notably, we identified the first NDM-1 and IMP-1 co-producing E. cloacae, carrying plasmids of several incompatibility (Inc) groups, including IncHI2, IncHI2A, and IncN. Most isolates showed decreased expression of ompC and/or ompF, and contained a broad distribution of ESBLs and AmpC β-lactamases. …”

Image 2_The green tea component (−)-epigallocatechin-3-gallate protects against cytokine-induced epithelial barrier damage in intestinal epithelial cells.tif by Rita Rosenthal (285303)

“…Among other beneficial effects, EGCG was shown to be protective in inflammatory bowel disease (IBD), a condition associated with barrier dysfunction. …”

Increased 14-3-3β and γ protein isoform expressions in parasitic eosinophilic meningitis caused by <i>Angiostrongylus cantonensis</i> infection in mice by Hung-Chin Tsai (673178)

“…</p><p>Mice were orally infected with 50 <i>A</i>. <i>cantonensis</i> L3 via an oro-gastric tube and sacrificed every week for 3 consecutive weeks after infection. …”

Image 1_The green tea component (−)-epigallocatechin-3-gallate protects against cytokine-induced epithelial barrier damage in intestinal epithelial cells.tif by Rita Rosenthal (285303)

“…Among other beneficial effects, EGCG was shown to be protective in inflammatory bowel disease (IBD), a condition associated with barrier dysfunction. …”

Table_3_Revealing the novel autophagy-related genes for ligamentum flavum hypertrophy in patients and mice model.docx by Peng Li (69518)

“…Using transmission electron microscopy, quantitative RT-PCR, Western blotting, and immunohistochemistry, we identified six hub ARGs in clinical specimens and bipedal standing (BS) mouse model.</p>Results<p>A total of 70 potential differentially expressed ARGs were screened, including 50 up-regulated and 20 down-regulated genes. …”

Image_1_Efficacy and safety of transarterial chemoembolization plus antiangiogenic- targeted therapy and immune checkpoint inhibitors for unresectable hepatocellular carcinoma with... by Jin-Kai Feng (11197404)

“…Purpose<p>This study aimed to assess the efficacy and safety of a triple therapy that comprises transarterial chemoembolization (TACE), antiangiogenic-targeted therapy, and programmed death-1 (PD-1) inhibitors in a real-world cohort of patients with unresectable hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT).…”

Data_Sheet_1_Socioeconomic disparities associated with mortality in patients hospitalized for COVID-19 in Colombia.pdf by Oscar Ignacio Mendoza Cardozo (14856355)

“…Finally, the odds of death from COVID-19 in hospitalized patients gradually decreased as the pandemic evolved. In conclusion, socioeconomic disparities were a major risk factor for mortality in patients hospitalized for COVID-19 in Colombia.…”

Image_2_Palmitic Acid Methyl Ester and Its Relation to Control of Tone of Human Visceral Arteries and Rat Aortas by Perivascular Adipose Tissue.jpeg by Ning Wang (108353)

“…These effects were abolished by XE991 (30 μM), but not 4-aminopyridine (2 mM) or NDGA (10 μM), a lipoxygenases inhibitor. The cytochrome P450 epoxygenase inhibitor 17-octadecynoic acid (ODYA 10 μM) and the soluble epoxide hydrolase inhibitor 12-(3-adamantan-1-ylureido)-dodecanoic acid (AUDA 10 μM) slightly decreased PAME relaxations. …”

Table_1_Revealing the novel autophagy-related genes for ligamentum flavum hypertrophy in patients and mice model.docx by Peng Li (69518)

“…Using transmission electron microscopy, quantitative RT-PCR, Western blotting, and immunohistochemistry, we identified six hub ARGs in clinical specimens and bipedal standing (BS) mouse model.</p>Results<p>A total of 70 potential differentially expressed ARGs were screened, including 50 up-regulated and 20 down-regulated genes. …”