Search alternatives:
point decrease » point increase (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
point decrease » point increase (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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Human cochlin bound to <i>N</i>-sulfated heparin and mutations in DFNA9 patients decreased binding affinity.
Published 2022“…(B) <i>N</i>-desulfated, <i>N</i>-acetylated heparin significantly decreased binding affinity for cochlin. Each wild-type and mutated cochlin reporter cell was cultured in a well coated with (C) heparin, (D) <i>N</i>-desulfated, <i>N</i>-acetylated heparin, (E) 6-<i>O</i>-desulfated heparin, or (F) 2-<i>O</i>-desulfated heparin for 18 h at 37°C and β-galactosidase expression was monitored calorimetrically. …”
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