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Ether induces proteotoxic stress, leading to a decrease in Trx protein and an increase in Hsp90 clients that are joint targets of Trx and Ubx.
Published 2024“…<b>(N)</b> GO enrichment analysis of proteins that increased (red) and decreased by ether, as determined by proteomics profiles of exposed and non-exposed embryos. …”
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Significantly decreased levels of CD4<sup>+</sup>CD25<sup>+</sup> Treg cells in arthropathic Tax transgenic mice.
Published 2011“…(D) The percentage of CD4<sup>+</sup>CD25<sup>+</sup>Foxp3<sup>+</sup> Treg cells in CD4<sup>+</sup> T cells did not differ between arthropathic Tax transgenic mice and non-transgenic mice (n = 6 per group). (E) Arthropathic Tax transgenic mice showed a significant decrease in the percentage of CD4<sup>+</sup>CD25<sup>+</sup>Foxp3<sup>+</sup> Treg cells in splenic lymphocytes compared with non-transgenic mice (n = 6 per group), ** <i>P</i><0.01.…”